Senior Scientist

3 weeks ago


Cambridge, United States IMS People Full time
Job DescriptionJob Description

Job Title: Scientist - III (Senior) 
Duration: 23 Month Contract
Location: ONSITE - 320 Bent St 3rd Floor, Cambridge, MA 02141  - Position is in Cambridge, MA. This is a lab based onsite role. Candidates must be flexible and able to accommodate the change.
Shift Hours: M-F 8:00am -5:00pm

 Final Interviews will be onsite - Please make sure candidates are comfortable coming onsite and prepare presentation for 30 minutes.

Please Note: Kindly ensure candidates with PHD/Masters degree have publications links listed on the resumes. Resume is well proofread, correct format is bring used to submit the resumes in the VMS.

Day to Day:

  • Muscle work
  • Heavy wet lab-based position.
  • Culture the cells.
  • Work on Assay development.
  • Role requires more precision to design experiments, culture cells and assay development.
  • Team environment
  • Discuss the experimental strategy with other scientists.
  • Develop experimental plan (discuss, analyse, and present experimental plans)
  • Present the data in a group meeting to other scientists.
  • Use ELN

Qualifications:
Education requirements:

  • BS with 5+ years of experience/Masters with 3+ years of experience/PHD with 1+ year of experience in a wet lab setting.
  • Candidates with a background in muscle biology will be given preference.

Required experience and skills:

  • Skilled in cell culturing and differentiation of stem cells into specific lineages. 
  • Experience with gene manipulation technologies such as CRISPR, siRNA, ASOs, lentivirus, and AAVs.
  • Expertise in molecular biology techniques including RNA extraction, qPCR, ELISA/MSD, and ICC.
  • Critical thinking with an ability to formulate experimental strategies.
  • Effective in working independently and collaboratively within a team. 
  • Outstanding verbal and written communication skills.

Responsibilities:

  • Scientist – in-vitro disease modeling Genome Sciences department in MRL is looking for a motivated scientist to lead the identification and validation of new genetic targets for various cardiometabolic diseases including Type 2 Diabetes (T2D), Obesity, Atherosclerosis, Retinal diseases, and vascular diseases.
  • This individual will play a pivotal role as a member of the discovery team, contributing to the development of innovative models for screening drug targets.

Job responsibilities:

  • Establish stem cell-based in-vitro disease platforms.
  • Design assays using high content imaging techniques to facilitate screening of small molecules and genetic modifications using CRISPR.
  • Perform lab experiments, interpret data, and effectively communicate findings. 
  • Collaborate with cross-functional teams in therapeutic and functional areas. 
  • Maintain electronic lab notebook and sample inventories.

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