Director, Clinical Science
4 weeks ago
Our Culture: Why work with us?
At Foghorn Therapeutics, we believe in “People First, Mission Always.”
We put “People First” because we know our people are the key to everything we will accomplish. We value the diversity of background, ideas, perspectives and experiences that our team members bring to Foghorn Therapeutics – demonstrated by our community speaking more than 22 languages and representing over 24 nationalities. We value our teammates as people, not just as employees – validated by our actions that let our people know that we care about them, their families, and their lives.
We say “Mission Always” because we know a relentless commitment to our mission will make a difference in the lives of others. We believe our success will come from evaluating the data to follow the science. We work hard to develop a new class of therapies that could improve the lives of over 2.5 million people with cancer.
Our culture is focused on succeeding through the evaluation of data, not people. And in that, relationships can flourish and develop.
Our Science:
The groundbreaking science behind our therapies continues to yield vital insights into diseases that have confounded physicians and researchers. Our core scientific approach is centered on the chromatin regulatory system, which opens and closes the right sections of DNA at the right time. Breakdowns in the chromatin regulatory system lead to a wide range of diseases, including cancer, impacting millions of people.
Our proprietary Gene Traffic Control® platform is a powerful tool for understanding and modulating the chromatin regulatory system. We are pursuing multiple treatments for breakdowns in this system. We are the only company with the ability to study and target the chromatin regulatory system at scale, in context, and in an integrated way.
The Role:
As the Director of Clinical Science at Foghorn, a leader in the development of innovative oncology treatments, you'll guide the advancement of clinical programs that transform the lives of patients. Leading the strategic design, implementation, and analysis of clinical trials, you'll uphold the highest standards of scientific rigor and ethical research. Your insights will drive critical decision-making, ultimately bringing novel and life-changing therapies to those in need.
This is a hybrid position requiring the employee to visit the office weekly.
In This Role, You'll Get To:
- Champion Strategic Clinical Development: Provide expert guidance on Phase I/II/III programs, crafting protocols and clinical development plans that advance scientific objectives and rigorously adhere to regulatory standards.
- Analyze and Interpret Clinical Data: Diligently oversee the collection and analysis of clinical data, using sophisticated tools to ensure data integrity and offer actionable insights that drive program decisions.
- Optimize Trial Processes: Collaborate with data management to streamline clinical databases and data collection, maximizing efficiency and accuracy.
- Uphold Regulatory Compliance: Safeguard trial integrity by meticulously monitoring adherence to all ethical and regulatory guidelines, swiftly addressing potential issues.
- Contribute to Regulatory Submissions: Support the preparation of scientifically sound and compliant documents for regulatory interactions.
- Disseminate Clinical Knowledge: Support the creation of presentations, publications, and conference materials that advance understanding within the field.
- Nurture Cross-Functional Excellence: Build strong partnerships throughout the organization, bridging the gap between clinical science, pharmacology, medicine, and regulatory functions.
Requirements
About You:
- Education: A Master's Degree, Ph.D., PharmD, or a B.A./B.S. with commensurate clinical research experience is required.
- Knowledge: Robust understanding of GCP and ICH guidelines.
- Experience: 7+ years of proven experience in clinical trial management and oversight, specifically within oncology. Demonstrated success in leading Phase I-III clinical trials. Track record of analyzing and interpreting clinical data, including the use of data review software.
- Skills:
- Proven analytical prowess, including proficiency in statistical analysis and data interpretation related to clinical trials.
- Command of clinical study design, including protocol and amendment development.
- Comprehensive knowledge of regulatory guidelines (e.g., FDA, EMA, ICH, GCP).
- Fluency in data management tools and processes, including the ability to oversee database setups and modifications.
- Strong leadership and team management capabilities, with a focus on mentoring staff and leading cross-functional teams.
- Drive to embrace new challenges and responsibilities.
- Exceptional written and verbal communication, including scientific writing and regulatory presentations.
Benefits
Foghorn Therapeutics is pleased to provide you and your family with a comprehensive suite of benefits, including:
- Highly competitive and inclusive medical, dental and vision coverage options
- BCBS PPO and PPO HSA plans
- BCBS Dental Plan
- EyeMed Vision Plan
- FSA and HSA for medical expenses and dependent care expenses
- 401(k) Program via Fidelity with the company match
- Corporate Wellness Program
- Unlimited Paid Time Off policy
- Winter shut down
- 12 weeks of 100% paid parental leave for birthing/primary parent and primary guardian in case of adoption and 3 weeks of 100% paid parental leave for non-birthing/non-primary parent/guardian.
- Paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
- Free parking, subsidized commuter passes, or a $100 monthly stipend for walking/biking to work
- Company lunches on Wednesdays
Foghorn Therapeutics is a smoke-free, alcohol-free and drug-free work environment.
Foghorn is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Foghorn Therapeutics will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
-
Director, Clinical Science
3 weeks ago
Cambridge, United States Blueprint Medicines Full timeHow will your role help us transform hope into reality? The Director, Clinical Science will provide scientific support for all Clinical Development activities involving the conduct of clinical studies, including: clinical development plans, study design and feasibility, data collection requirements, analysis plans, preparation of meeting materials and...
-
Director, Clinical Science
3 weeks ago
Cambridge, United States Blueprint Medicines Full timeHow will your role help us transform hope into reality?Apply below after reading through all the details and supporting information regarding this job opportunity.The Director, Clinical Science will provide scientific support for all Clinical Development activities involving the conduct of clinical studies, including: clinical development plans, study design...
-
Director, Clinical Science
2 months ago
Cambridge, United States Meet Full timeDirector, Clinical ScienceAn exciting position with an innovative and clinical stage biopharma based in Massachusetts. This company is focused on oncology & have recently received over $100 million in new funding.Job Description:This role is hybrid once a week in Cambridge. This is a highly visible role, reporting to the CMO, tasked with growing out the...
-
Director, Clinical Science
2 months ago
Cambridge, United States Meet Full timeDirector, Clinical ScienceAn exciting position with an innovative and clinical stage biopharma based in Massachusetts. This company is focused on oncology & have recently received over $100 million in new funding.Job Description:This role is hybrid once a week in Cambridge. This is a highly visible role, reporting to the CMO, tasked with growing out the...
-
Senior Director Clinical Science Lead
4 days ago
Cambridge, United States Bayer Full timeAt Bayer we’re visionaries, driven to solve the world’s toughest challenges and striving for a world where 'Health for all Hunger for none’ is no longer a dream, but a real possibility. We’re doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our...
-
Director, Clinical Science
2 months ago
Cambridge, United States Foghorn Therapeutics Full timeJob DescriptionJob DescriptionOur Culture: Why work with us?At Foghorn Therapeutics, we believe in “People First, Mission Always.” We put “People First” because we know our people are the key to everything we will accomplish. We value the diversity of background, ideas, perspectives and experiences that our team members bring to Foghorn Therapeutics...
-
Director, Digital Quantitative Sciences
1 month ago
Cambridge, United States Pfizer Full timeROLE SUMMARYThe Director, Digital Quantitative Sciences is responsible for ensuring sound statistical thinking and methods are utilized in the discovery and development of novel digital and imaging endpoints and for bringing the principles of objective decision-making into the development, validation, and implementation of industry-leading digital health...
-
Director, Digital Quantitative Sciences
1 month ago
Cambridge, Massachusetts, United States Pfizer Full timeROLE SUMMARYThe Director, Digital Quantitative Sciences is responsible for ensuring sound statistical thinking and methods are utilized in the discovery and development of novel digital and imaging endpoints and for bringing the principles of objective decision-making into the development, validation, and implementation of industry-leading digital health...
-
Cambridge, Massachusetts, United States Massachusetts Institute of Technology Full timeDeputy Director of Science and TechnologyWe are seeking a highly skilled and experienced individual to serve as Deputy Director of Science and Technology at the Massachusetts Institute of Technology (MIT). This is a key leadership position that will play a critical role in driving the organization's mission and vision forward.About the RoleAssume a...
-
Clinical Science Leader
6 days ago
Cambridge, Massachusetts, United States Foghorn Therapeutics Full timeAbout the RoleWe are seeking a highly experienced and skilled Director of Clinical Science to join our team at Foghorn Therapeutics. As a key member of our clinical development team, you will be responsible for leading the strategic design, implementation, and analysis of clinical trials.Key ResponsibilitiesProvide expert guidance on Phase I/II/III programs,...
-
Deputy Director of Science and Technology
2 days ago
Cambridge, Massachusetts, United States Massachusetts Institute of Technology Full time**Job Summary**Massachusetts Institute of Technology (MIT) is seeking a highly qualified individual to serve as the Deputy Director of Science and Technology for the MIT Energy Initiative (MITEI). As a key member of the MITEI team, the successful candidate will play a critical role in advancing the organization's mission to create a clean, affordable, and...
-
Director, Clinical Biomarkers
3 months ago
Cambridge, Massachusetts, United States Moderna, Inc. Full timeThe Role:Moderna is seeking a Director of Clinical Biomarkers to serve as a scientific leader and point of contact for clinical teams in the Infectious Disease (ID) space with responsibilities for developing and driving pivotal biomarker plans across clinical stage ID programs. This position reports to Modernas Sr. Director of Infectious Disease, Clinical...
-
Director, Clinical Operations
4 weeks ago
Cambridge, United States Foghorn Therapeutics Full timeJob DescriptionJob DescriptionOur Culture: Why work with us?At Foghorn Therapeutics, we believe in “People First, Mission Always.” We put “People First” because we know our people are the key to everything we will accomplish. We value the diversity of background, ideas, perspectives and experiences that our team members bring to Foghorn Therapeutics...
-
Director, Clinical Operations
2 months ago
Cambridge, United States Foghorn Therapeutics Full timeJob DescriptionJob DescriptionOur Culture: Why work with us?At Foghorn Therapeutics, we believe in “People First, Mission Always.” We put “People First” because we know our people are the key to everything we will accomplish. We value the diversity of background, ideas, perspectives and experiences that our team members bring to Foghorn Therapeutics...
-
Director, Clinical Operations
7 days ago
Cambridge, United States Foghorn Therapeutics Full timeJob DescriptionJob DescriptionOur Culture: Why work with us?At Foghorn Therapeutics, we believe in “People First, Mission Always.” We put “People First” because we know our people are the key to everything we will accomplish. We value the diversity of background, ideas, perspectives and experiences that our team members bring to Foghorn Therapeutics...
-
Healthcare Facilities Director
4 days ago
Cambridge, Vermont, United States Clinical Management Consultants Full timeJob Summary: Clinical Management Consultants is seeking an experienced Hospital Facilities Director to oversee maintenance, biomedical services, security, and housekeeping across our hospital campus.Key Responsibilities:Set departmental goals and standardsManage construction projectsEnsure compliance with state and federal regulationsMaintain a safe and...
-
Cambridge, Massachusetts, United States Massachusetts Institute of Technology Full timeJob SummaryMassachusetts Institute of Technology seeks a highly qualified Deputy Director to play a crucial leadership role in advancing the center's mission to explore and develop fusion energy and plasma science.Key ResponsibilitiesOversee large-scale scientific infrastructure and promote a culture of innovation and excellence.Strategically plan and...
-
Cambridge, United States Pfizer Full timeROLE SUMMARYThe Associate Director, Digital Quantitative Sciences is responsible for ensuring sound statistical thinking and methods are utilized in the discovery and development of novel digital and imaging endpoints; bringing the principles of objective decision-making into the development, validation, and implementation of industry-leading digital health...
-
Cambridge, Massachusetts, United States Pfizer Full timeROLE SUMMARYThe Associate Director, Digital Quantitative Sciences is responsible for ensuring sound statistical thinking and methods are utilized in the discovery and development of novel digital and imaging endpoints; bringing the principles of objective decision-making into the development, validation, and implementation of industry-leading digital health...
-
Associate Director, Clinical Scientist
2 weeks ago
Cambridge, United States Bicycle Therapeutics Full timeBicycle Therapeutics is a clinical-stage biopharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry....
