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Computational Biologist

2 months ago

Bethesda, United States PriceSenz Full time
Job DescriptionJob Description

Location : IC: NINDS Street: 10 Centre Dr Bldg.: NIHBC 10 - CRC Room: 7C103 City: Bethesda State & Zip: MD 20892

Weekly Hours - FT: 30-40 hours per week Total No. of Hours : 40

Overall Position Summary and Objectives

To study retroviral elements in the human genome and associated somatic mutations in neurodegenerative diseases, such as Amyotrophic Lateral Sclerosis, Parkinson syndromes, and Alzheimer's disease. The incumbent will have access to long-read sequences from a large cohort of patients and controls, super computer (biowulf) and a robust intellectual environment of like-minded researchers with complementary skill sets. Prior experience with retroviral elements is desirable but not necessary.

Min Education - Master's

Certifications & Licenses

  • Machine Learning Certification

Skills (Ranked by Priority)

  1. Single Cell RNA-Sequencing
  2. Next gen sequencing data analysis: Bulk RNA-Sequencing
  3. Microarray data analysis

Software

  • PowerPoint
  • Outlook

Field of Study

  • Genetics

Statement of Work Details

Provides programming and troubleshooting support to the Federal Government in the dissemination of research data.

  • Serve as bioinformatics expert and coordinate with teams of biologists to conduct experimental queries and/or perform portions of studies using complex procedures and techniques common to modern bioinformatics.
  • Provide broad-based programming and analytic support for a wide variety of bioinformatic and research projects.

Performs computations on research data analysis.

  • Perform computational analysis of, and interpret results.
  • Provide reports based on analysis of scientific data.

Works with staff on scientific programming and experimental design.

  • Collaborate with scientists to design, analyze, manage and interpret all types of data.
  • Design and execute computational experiments.

Records observations and report results at weekly laboratory meetings.

  • Maintain proper and detailed documentation of the analysis performed and report results at lab meetings.
  • Prepare scientific reports and progress reports; assemble data to prepare tables, graphs and slides; conduct scientific and program related information searches and report results.
  • Organize laboratory notebook or computer database to record results of calculations. Share results at lab meetings.

Provides statistical support / analysis on research data.

  • Devise novel methods of statistical analysis for collected data.
  • Perform data processing and data analysis with existing computational and statistical methods.
  • Assist in evaluating and interpreting results for validity and scientific meaning.

Provides research / service goals in the context of the laboratory's overall mission.

  • Work with staff on the development and maintenance of bioinformatics tools, scripts and pipe-lines for data.

Evaluates new types of experimental approaches to protocols based on knowledge of scientific literature, available facilities and research needs.

  • Research and review literature to retrieve targeted clinical or scientific information, including novel statistical methods, from publicly available resources.
  • Identify new tools and resources for reaching biologically meaningful conclusions.

Independently coordinates the training of personnel in the use of scientific software applications, statistical software applications and programmatic software applications.

  • Instruct staff in computational analysis of data.