Senior Bioprocess Engineer

1 week ago

Boston, United States Arcaea Full time
Job DescriptionJob Description

Arcaea is a biology-first beauty company building a new ingredient toolset for the beauty and personal care industry. We are creating pioneering ingredients, products, and stories accessible uniquely through biology.

Arcaea is building a new ingredient toolset for the beauty and personal care industry - one rooted in biotechnology with the aim of delivering radical performance and unparalleled sustainability that will also present new opportunities for storytelling.

Arcaea is seeking an experienced DSP Engineer to join our team and play a critical role in developing our ingredient toolset for the beauty and personal care industry. As a member of the Arcaea team, you will be responsible for leading Arcaea's downstream process development and scaling up activities.

No candidate will meet every single desired qualification. If your experience looks a little different from what we've identified and you think you can bring value to the role, we'd love to learn more about you

WHAT YOU WILL DO:

  • Lead the design, development, and implementation of downstream processes for the purification of bioactive ingredients
  • Apply your proficiency in a diverse range of downstream unit operations, such as chromatography (affinity, ion exchange, HIC, SEC, etc.), membrane separation processes (depth filtration, ultrafiltration/diafiltration, tangential flow filtration, and sterile filtration), centrifugation, lyophilization, spray drying and other relevant techniques.
  • Conduct hands on troubleshooting, process feasibility and process optimization experiments in relation to downstream purification and recovery processes
  • Build a science-based understanding of processes to define critical process parameters and establish acceptance criteria
  • Application of statistical data analysis in development, including design of experiments (DoE), multivariate analysis.
  • Assist with cost modeling analyses as needed.
  • Participate in tech-transfer activities with CDMO and CMOs and build strong relationships with collaborating companies.
  • Showcase your proven ability to scale up bioprocesses from laboratory-scale to pilot-scale and eventually to full-scale production.
  • Maintain meticulous documentation of experimental procedures, results, and process parameters.
  • Ensure compliance with industry standards and regulatory guidelines governing the production of cosmetic ingredients.
  • Develop technical insights based on research and scientific literature
  • Stay informed about the latest advancements in downstream processing technologies, assessing their applicability to elevate our processes.
  • Communicate technical information to internal teams and/or external parties in the form of oral and written correspondence, presentations, and reports
  • Work effectively and efficiently on a tight deadline without drama or ego

WHAT WE SEEK:

  • MS/PhD in chemical engineering, life sciences, biotechnology, or equivalent experience
  • 5+ years of experience in downstream processing, with a variety of unit operations
  • Successful track record of developing and scaling up industrial biotech DSP processes.
  • Proven ability to manage projects
  • Experience with tech transfer to CDMO/CMOs.
  • Proficiency in process simulation and modeling tools is advantageous.
  • Strong problem-solving and analytical skills.
  • Highly independent with the ability to work with cross functional teams in a fast-paced environment.
  • Delivering on projects, on time.
  • Effective communicator, can explain complex science in layman terms.
  • Strong interpersonal skills.
  • Startup experience preferred

We are committed to diversity, equality, and inclusion in all its practices. It is the policy of Arcaea to provide equal employment opportunities to all employees and employment applicants.



We feel that it's important to point out the obvious here – there's a serious lack of diversity in both the scientific fields and beauty industry, and that needs to change. Our goal is to help drive that change. We are deeply committed to diversity, equality, and inclusion in all its practices, especially when it comes to growing our team. Our culture promotes inclusion and embraces how rewarding it is to work with people from all walks of life.

No candidate will meet every single desired qualification. If your experience looks a little different from what we've identified and you think you can bring value to the role, we'd love to learn more about you

We're working with the powerful biological engineering platform at Ginkgo Bioworks, so we must remain mindful of the many ways our technology can – and will – impact people around the world. Ginkgo and Arcaea care about how this platform and the products created are used. Having a diverse team to build it gives us the best chance that it's something we'll be proud of as it continues to grow. Therefore, it's critical that we incorporate the diverse voices and visions of all those who play a role in the future of biology in every industry.

We are committed to diversity, equality, and inclusion in all its practices. It is the policy of Arcaea to provide equal employment opportunities to all employees and employment applicants.

Agency and Third Party Recruiter Notice: Agencies that submit a resume to Arcaea must have a current executed Arcaea Agency Agreement executed by the Director, People Operations. In addition Agencies may only submit candidates to positions for which they have been invited to do so by an Arcaea Recruiter. All resumes must be sent to the Arcaea Recruiter under these terms or they will not be considered.

If you have a disability under the Americans with Disabilities Act or similar law, or you require religious accommodation, and you wish to discuss potential accommodations related to applying for employment at our company, please contact recruiting@arcaea.com.

Arcaea participates in E-verify to determine employment eligibility.

Disclaimer: This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee.

  • Director, Bioprocess

    Found in: Jooble US O C2 - 2 weeks ago

    Boston, MA, United States EPM Scientific - Phaidon International Full time

    Director, Bioprocess Company Summary: A small, clinical-stage biopharmaceutical research company is currently seeking a driven, motivated, and enthusiastic Director, Bioprocess. This position is located the Greater Boston area. You will play a key role in providing technical expertise for leading and developing early-stage clinical programs. The...

  • Senior Downstream Production Engineer, AAV Bioprocessing and Development

    Found in: Jooble US O C2 - 2 weeks ago

    Boston, MA, United States Ginkgo Bioworks Full time

    Senior Downstream Production Engineer, AAV Bioprocessing and Development (DSP) Ginkgo is looking for a highly motivated Senior Downstream Production Engineer, Cell and Gene Therapy to join the Foundry’s expanding High-throughput Screening (HTS) team. In this role, you will play a critical role to help establish, plan, develop and execute bioprocessing of...

  • Senior Production Engineer I

    Found in: Jooble US O C2 - 2 weeks ago

    Boston, MA, United States Ginkgo Bioworks Full time

    Senior Downstream Production Engineer, AAV Bioprocessing and Development (DSP) Ginkgo is looking for a highly motivated Senior Downstream Production Engineer, Cell and Gene Therapy to join the Foundry’s expanding High-throughput Screening (HTS) team. In this role, you will play a critical role to help establish, plan, develop and execute bioprocessing of...

  • Senior Bioprocess Engineer

    Found in: Jooble US O C2 - 2 weeks ago

    Boston, MA, United States Arcaea Full time

    Arcaea is building a new ingredient toolset for the beauty and personal care industry - one rooted in biotechnology with the aim of delivering radical performance and unparalleled sustainability that will also present new opportunities for storytelling. Arcaea is seeking an experienced DSP Engineer to join our team and play a critical role in developing...

  • Senior Bioprocess Engineer

    1 week ago

    Boston, United States Arcaea Full time

    Arcaea is a biology-first beauty company building a new ingredient toolset for the beauty and personal care industry. We are creating pioneering ingredients, products, and stories accessible uniquely through biology. Arcaea is building a new ingredient toolset for the beauty and personal care industry - one rooted in biotechnology with the aim of delivering...

  • Director, Bioprocess Development

    1 week ago

    Boston, United States HilleVax, Inc. Full time

    HilleVax is a clinical-stage biopharmaceutical company focused on developing and commercializing novel vaccines. Our initial program, HIL-214, is a virus-like particle (VLP) based vaccine candidate for the prevention of moderate-to-severe acute gastroenteritis (AGE) caused by norovirus infection. It is estimated that norovirus causes nearly 700 million cases...

  • Director, Bioprocess Development

    1 week ago

    Boston, United States CareerBuilder Full time

    HilleVax is a clinical-stage biopharmaceutical company focused on developing and commercializing novel vaccines. Our initial program, HIL-214, is a virus-like particle (VLP) based vaccine candidate for the prevention of moderate-to-severe acute gastroenteritis (AGE) caused by norovirus infection. It is estimated that norovirus causes nearly 700 million cases...

  • Director, Bioprocess Development

    Found in: Jooble US O C2 - 2 weeks ago

    Boston, MA, United States Hillevax Full time

    HilleVax is a clinical-stage biopharmaceutical company focused on developing and commercializing novel vaccines. Our initial program, HIL-214, is a virus-like particle (VLP) based vaccine candidate for the prevention of moderate-to-severe acute gastroenteritis (AGE) caused by norovirus infection. It is estimated that norovirus causes nearly 700 million...

  • Process Development Engineering Senior Scientist

    Found in: Talent US C2 - 2 weeks ago

    Boston, United States Vertex Full time

    Job DescriptionGeneral Summary:Vertex has established a new research site in Boston Seaport where research, development, and clinical manufacturing for cell and genetic therapies will be primarily based. Cell and genetic therapies represent two rapidly emerging therapeutic modalities with the potential to treat—and even cure—several of thediseases Vertex...

  • Project Engineer

    1 week ago

    Boston, United States Trinity Consultants Full time

    ADVENT's services include process engineering, automation engineering, project engineering, HVAC/facility system design, process development, start up and commissioning, validation and compliance consulting for distinguished and successful biotechnology and pharmaceutical manufacturing companies. The successful candidate will work with a group of engineers...

  • Project Engineer

    4 days ago

    Boston, United States Trinity Consultants Full time

    ADVENT's services include process engineering, automation engineering, project engineering, HVAC/facility system design, process development, start up and commissioning, validation and compliance consulting for distinguished and successful biotechnology and pharmaceutical manufacturing companies. The successful candidate will work with a group of engineers...

  • Project Engineer

    1 week ago

    Boston, United States Trinity Consultants - Advent Engineering Life Science Solutions Full time

    ADVENT's services include process engineering, automation engineering, project engineering, HVAC/facility system design, process development, start up and commissioning, validation and compliance consulting for distinguished and successful biotechnology and pharmaceutical manufacturing companies.The successful candidate will work with a group of engineers...

  • Project Engineer

    Found in: Appcast Linkedin GBL C2 - 2 weeks ago

    Boston, United States Trinity Consultants - Advent Engineering Life Science Solutions Full time

    ADVENT's services include process engineering, automation engineering, project engineering, HVAC/facility system design, process development, start up and commissioning, validation and compliance consulting for distinguished and successful biotechnology and pharmaceutical manufacturing companies.The successful candidate will work with a group of engineers...

  • Senior Director, Head of Drug Substance

    Found in: Appcast Linkedin GBL C2 - 2 weeks ago

    Boston, United States Astria Therapeutics, Inc. Full time

    Title: Senior Director, Head of Drug Substance Position Overview:Astria Therapeutics is dedicated to bringing hope with life-changing therapies to patients and families affected by allergic and immunological diseases. Astria’s pipeline includes our lead program, STAR-0215, a monoclonal antibody inhibitor of plasma kallikrein in clinical development for the...

  • Senior Director, Head of Drug Substance

    1 week ago

    Boston, United States Astria Therapeutics, Inc. Full time

    Title: Senior Director, Head of Drug Substance Position Overview:Astria Therapeutics is dedicated to bringing hope with life-changing therapies to patients and families affected by allergic and immunological diseases. Astria’s pipeline includes our lead program, STAR-0215, a monoclonal antibody inhibitor of plasma kallikrein in clinical development for the...

  • Senior Director, Head of Drug Substance

    Found in: Appcast US C2 - 1 week ago

    Boston, United States Astria Therapeutics, Inc. Full time

    Title: Senior Director, Head of Drug Substance Position Overview:Astria Therapeutics is dedicated to bringing hope with life-changing therapies to patients and families affected by allergic and immunological diseases. Astria’s pipeline includes our lead program, STAR-0215, a monoclonal antibody inhibitor of plasma kallikrein in clinical development for the...

  • Senior Director, Head of Drug Substance

    Found in: Appcast US C2 - 1 day ago

    Boston, United States Astria Therapeutics, Inc. Full time

    Title: Senior Director, Head of Drug Substance Position Overview:Astria Therapeutics is dedicated to bringing hope with life-changing therapies to patients and families affected by allergic and immunological diseases. Astria’s pipeline includes our lead program, STAR-0215, a monoclonal antibody inhibitor of plasma kallikrein in clinical development for the...

  • Senior Director, Head of Drug Substance

    2 days ago

    Boston, United States Astria Therapeutics, Inc. Full time

    Title: Senior Director, Head of Drug Substance Position Overview:Astria Therapeutics is dedicated to bringing hope with life-changing therapies to patients and families affected by allergic and immunological diseases. Astria’s pipeline includes our lead program, STAR-0215, a monoclonal antibody inhibitor of plasma kallikrein in clinical development for the...

  • Senior Director, Head of Drug Substance

    Found in: Appcast Linkedin GBL C2 - 2 days ago

    Boston, United States Astria Therapeutics, Inc. Full time

    Title: Senior Director, Head of Drug Substance Position Overview:Astria Therapeutics is dedicated to bringing hope with life-changing therapies to patients and families affected by allergic and immunological diseases. Astria’s pipeline includes our lead program, STAR-0215, a monoclonal antibody inhibitor of plasma kallikrein in clinical development for the...

  • Senior Mechanical Engineer

    5 days ago

    Boston, United States RMF Engineering, Inc. Full time

    Job DescriptionJob DescriptionDescription/Job SummarySenior Mechanical EngineerRMF Engineering, Inc. is seeking a Senior Mechanical Engineer to join our Boston Division. Enthusiastic and energetic, the successful candidate will work with a cross-functional team on mechanical building systems and projects. The role is responsible for contributing to the...