Senior Bioprocess Engineer

Found in: Jooble US O C2 - 2 weeks ago

Boston MA, United States Arcaea Full time

Arcaea is building a new ingredient toolset for the beauty and personal care industry - one rooted in biotechnology with the aim of delivering radical performance and unparalleled sustainability that will also present new opportunities for storytelling.

Arcaea is seeking an experienced DSP Engineer to join our team and play a critical role in developing our ingredient toolset for the beauty and personal care industry. As a member of the Arcaea team, you will be responsible for leading Arcaea's downstream process development and scaling up activities.

No candidate will meet every single desired qualification. If your experience looks a little different from what we’ve identified and you think you can bring value to the role, we’d love to learn more about you

WHAT YOU WILL DO:

  • Lead the design, development, and implementation of downstream processes for the purification of bioactive ingredients
  • Apply your proficiency in a diverse range of downstream unit operations, such as chromatography (affinity, ion exchange, HIC, SEC, etc.), membrane separation processes (depth filtration, ultrafiltration/diafiltration, tangential flow filtration, and sterile filtration), centrifugation, lyophilization, spray drying and other relevant techniques.
  • Conduct hands on troubleshooting, process feasibility and process optimization experiments in relation to downstream purification and recovery processes
  • Build a science-based understanding of processes to define critical process parameters and establish acceptance criteria
  • Application of statistical data analysis in development, including design of experiments (DoE), multivariate analysis.
  • Assist with cost modeling analyses as needed.
  • Participate in tech-transfer activities with CDMO and CMOs and build strong relationships with collaborating companies.
  • Showcase your proven ability to scale up bioprocesses from laboratory-scale to pilot-scale and eventually to full-scale production.
  • Maintain meticulous documentation of experimental procedures, results, and process parameters.
  • Ensure compliance with industry standards and regulatory guidelines governing the production of cosmetic ingredients.
  • Develop technical insights based on research and scientific literature
  • Stay informed about the latest advancements in downstream processing technologies, assessing their applicability to elevate our processes.
  • Communicate technical information to internal teams and/or external parties in the form of oral and written correspondence, presentations, and reports
  • Work effectively and efficiently on a tight deadline without drama or ego

WHAT WE SEEK:

  • MS/PhD in chemical engineering, life sciences, biotechnology, or equivalent experience
  • 5+ years of experience in downstream processing, with a variety of unit operations
  • Successful track record of developing and scaling up industrial biotech DSP processes.
  • Proven ability to manage projects
  • Experience with tech transfer to CDMO/CMOs.
  • Proficiency in process simulation and modeling tools is advantageous.
  • Strong problem-solving and analytical skills.
  • Highly independent with the ability to work with cross functional teams in a fast-paced environment.
  • Delivering on projects, on time.
  • Effective communicator, can explain complex science in layman terms.
  • Strong interpersonal skills.
  • Startup experience preferred

We are committed to diversity, equality, and inclusion in all its practices. It is the policy of Arcaea to provide equal employment opportunities to all employees and employment applicants.

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