Scientist III

Responsibilities:

• Excellent employment opportunity for a Scientist III in the Ridgefield, CT area.
• Design, implement and/or deploy NGS data analysis workflows for data processing, visualization, integration and mining to support novel therapeutic target identification and disease biomarker discovery
• Data Analysis: Implement methods for omics data analysis, and interpretation of genomic data sets (e.g., bulk RNA-seq, scRNA-seq, ATAC-Seq)
• Data Visualization: Fluency in contemporary data visualization methods like R Shiny, D3
• Data Integration: Analyzing diverse datasets (multi-omics) to find relevant drug discovery targets and downstream effects relevant to immune disease
• Data Mining: Internal, collaborative, and public databases to assist in the characterization of immune disease
• Select and benchmark methods and tools, define and perform appropriate QC measures
• Apply and develop innovative analysis approaches when standard methods are not adequate
• Interpret and present analysis results to coworkers and collaborators
• Follow relevant scientific literature to ensure use of optimal methods and understand emerging practices across the field
• Demonstrates the ability to interpret the outcome of experiments, propose appropriate follow-up, and may propose new avenues of investigation
• Communicates own work effectively orally and in writing; contributes to writing protocols, procedures, and technical reports
• Automate processing and results reporting and delivery
• Reports and treats data with a high level of integrity and ethics
• Complies with applicable regulations; Maintains proper records in accordance with SOPs and policies
  

Experience:

• Master's Degree from an accredited institution with one-plus (1+) years of experience in a related Scientific discipline (Computer Science, Genomics, Biostatistics or Bioinformatics preferred) OR Bachelor's Degree from an accredited institution with seven-plus (7+) years of experience in a STEM discipline.
• Strong Scientific understanding and experience in Bioinformatics
• Experience in Pharmaceutical research a plus
• The successful candidate will have experience with more than one of the following: analyzing next-generation sequencing (NGS), functional genomics, statistics for big data analysis, or multi-omics data integration
• Good knowledge of existing bioinformatics databases and file formats In-depth understanding of computational methods for NGS analysis and the usage of public data resources required
• Strong hands-on skills in relevant programming languages (e.g., R, Python, Shiny, UNIX/Linux, UNIX bash shell scripting, Nextflow), statistical software, cloud computing, visualization tools, and relevant R/Bioconductor packages
• Demonstrated ability to produce well-designed and documented code
• Familiarity with computational biology tools and experience working with computational biologists to solve problems
• Ability to troubleshoot both individually and as part of a team
• Excellent oral and written skills with the ability to communicate in an open, transparent, timely and consistent manner
• Skills: BIOINFORMATICS, BIOSTATISTICS, DATABASES, GENOMICS, LINUX
• Additional Skills: PYTHON, SCRIPTING, SHELL SCRIPTING, SHINY, UNIX, UNIX/LINUX, VISUALIZATION, WRITING PROTOCOLS, DATA ANALYSIS, DATA INTEGRATION, DATA MINING, DATA VISUALIZATION, DATASETS, DRUG DISCOVERY, INTEGRATION, INTEGRATOR, MARKETING ANALYSIS, PHARMACEUTICAL RESEARCH, RNA, SEQUENCING, SOPS, STATISTICS, THERAPEUTIC