Assistant/Associate Research Scientist

2 weeks ago

Coralville, United States Perspective Therapeutics Full time
Job DescriptionJob DescriptionObjectiveThe Assistant Research Scientist (ARS)/Associate Research Scientist (AsRS) is responsible for performing non-clinical studies in support of development of novel radiopharmaceuticals. The ARS/AsRS is also responsible for conducting in vitro and in vivo experiments to optimize the radiopharmaceutical drug molecules. The ARS/AsRS is responsible to conduct noon-clinical studies to evaluate the efficacy and safety of novel radiopharmaceuticals. This role also collaborates with colleagues from other departments on transitioning pipelines from preclinical stage to clinical stage.

Essential Functions
  • Drive non-clinical pipeline projects independently.
  • Design and conduct experiments to support the discovery and development of theranostic radiopharmaceuticals.
  • Perform routine cell culture with aseptic techniques.
  • Perform molecular and cellular assays, including western blotting, PCR, enzymatic assays, ligand binding assays (i.e., Kd/Bmax, IC50, EC50)
  • Prepare animal models to determine the PK/PD, therapeutic efficacy and toxicity of radiopharmaceuticals.
  • Analyze experimental results and generate high-quality reports.
  • Present research internally and externally and provide updates to cross-functional areas.
Qualifications
To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed below are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.Education/Experience
  • Master or PhD degree in Pharmacology, Pharmaceutical Sciences, Chemistry, Biochemistry Bioengineering, Biomedical Engineering or related field.
  • PhD degree or master’s degree with 5 years of working experience in research labs
  • 3+ years of working experience in cancer-related fields
  • 3+ years hands-on experience in developing and using murine models
  • Experience with biochemical or molecular/cellular biology, such as cell-based assays, enzymatic assays, aseptic cell cultures techniques, ELISA, qPCR, etc.
  • Experience with routine analytical equipment such as HPLC, TLC.
  • Experience with in vivo studies using laboratory animal models.
  • Experience with immunohistochemistry and flow cytometry
  • Experience with radioisotopes
  • Experience with wet chemistry, biology, cell culture.
Knowledge / Skill / Ability
  • Experience with GraphPad Prism, Microsoft Office, writing and following SOPs, data analysis, statistical analysis, oral presentation
  • Full range of motion and ability to use both hands mandated by machinery. High degree of manual dexterity.
  • Must be able to regularly lift 10 lb. weights, occasional lifting of up to 50 lbs.
  • Ability to maintain focus on a complex task for 4-6 hours at a time.
  • Excellent communications, interpersonal and collaboration skills, and ability to interact professionally with a wide range of individuals and organizations, internal and external.
  • Ability to work independently with minimal direction, and drive deliverables through to completion by deadlines provided.
  • Highly organized with strong attention to detail and commitment to high quality work.
  • Good interpersonal skills and ability to communicate information in a timely manner.
  • Comfort with various computer operating systems and laboratory operational platforms.
  • Ability to work within a corporate culture in which enthusiasm, respect, integrity, and teamwork are expected to the highest of standards.
Work EnvironmentThe work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
 
  • Must be willing to work in a facility producing radioactive materials and requiring all employees to participate in safety programs designed to minimize potential and/or actual exposure levels.
  • Must be able to work outside of regular work hours, including off shift, weekend, and holiday work as business needs require.
  • May be required to sit or stand for long periods of 8+ hours a day while performing duties. 
  • Occasional kneeling, crouching, twisting the upper body, bending, stooping, pushing, pulling, or reaching may be required.
  • Must possess good hand-eye coordination; close attention to detail is required.
  • Must be able to work indoors and outdoors with exposure to mechanical/moving parts, hazards including radioactive, corrosive, flammable and toxic material, dust, dirt, odors, and irritants.
  • Must be willing to wear a variety of Personal Protective Equipment (PPE), including eye and hearing protection, as needed.
  • Willingness to complete safety training within allotted timeframes, and work in a team-based environment.
Perspective Therapeutics provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws.

This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.

For information on Perspective Therapeutics, visit our website at: www.perspectivetherapeutics.com.
 

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