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Ocular Research Scientist

3 months ago

San Diego, United States RPM ReSearch Full time
Job DescriptionJob Description

Research Scientist/Study Director Ocular


Description:

We are seeking to find an accomplished Ocular Scientist with requirements of a broad knowledge of Ocular anatomy, physiology, and biochemistry to help develop and support in vivo models to screen small molecule, cell/gene therapy, as well as large molecule therapeutics and devices being developed for various ocular disorders.

Experience with ocular surgical, dosing and sampling techniques is necessary. The Ocular Research Scientist will assist in the development of protocols and criteria to effectively and efficiently carry out experiments.

The successful candidate will provide investigators with written and oral updates to scientific data generated during the conduct of the studies they oversee.

They may also participate in presentations at scientific meetings and/or preparation of manuscripts for presentations. Expertise to guide investigators on the approaches necessary to characterize the pharmacological effects of target molecules based on disease mechanisms is valuable.


Principal Duties and Responsibilities:


The Scientist will perform the following duties and responsibilities:


  • Assume the functional role of Principal Investigator or Study Director for preclinical ophthalmic studies.

  • Participate in study design and the development and generation of study protocols.

  • Manage the conduct of preclinical studies, evaluated the data, and assist in the writing and review of final reports.

  • Develop and execute research studies to expand research capabilities.

  • Develop and execute training programs for research associates and junior team members.

  • Write or revise Standard Operating Procedures (SOPs) to assure facility compliance with applicable regulations, client expectations, and current industry standards.

  • May be asked to serve on the Institutional Animal Care and Use Committee (IACUC)



Requirements:

  • Hands-on in vivo experience with multiple research species, at a minimum, rodent, and rabbit.

  • Ability to perform ocular injections, such as sub-conjunctival, sub-tendon, retrobulbar, intravitreal, and/or subretinal injections.

  • Experience with various imaging modalities, such as Optical coherence tomography (OCT), fundus photography, and fluorescein angiography.

  • Experience with other ocular techniques, such as intraocular pressure measurements, electroretinography (ERG), or optokinetic response (OKR).

  • Ability to perform duties and responsibilities with minimal supervision

  • Ability to understand Standard Operating Procedures (SOPs) and study protocols.

  • Must be flexible to work various schedules and hours as well as provide comprehensive, after-hours, and on-call coverage as needed.


Education

  • Graduate-level degree (M.S./ PhD/ DVM, VMD) required. Post Doctoral candidates are preferred.

  • Additional training in the GLPs and other applicable regulations required.


Experience

  • Minimum 3-6 years of experience required, based on education.