PRINCIPAL INVESTIGATOR

2 weeks ago

CA United States Tilda Research Full time
Why work at Tilda?

Our Mission

Tilda exists to accelerate the development of new medical treatments by providing every person easy access to clinical trials. As a tech-enabled clinical trial network, we build software and services to help pharma innovators better execute their clinical trial programs. Our work leads to faster cures and thus institutes a meaningful impact on millions of lives. You can help us realize that goal.

Who are we?

Tilda Research is an innovator in clinical research recruitment and trial execution. We operate a growing network of clinical research sites in the US, and our team has worked on over 250 pan-indication Phase I through IV studies. Our founders are successful serial entrepreneurs, with three of their past companies leading to IPOs (VMware, MobileIron) or exits (LexentBio acquired by Roche). We also build software and support clinical trial infrastructure to help pharmaceutical companies identify, enroll, and execute clinical trials efficiently.

Who are you?

We are seeking an experienced Principal Investigator (PI) with an internal or family medicine background to conduct and oversee studies. This role would for Tilda's Redlands, CA site. You will be responsible for ensuring the successful execution of research protocols, patient safety, maintaining compliance with regulatory requirements, and contributing to the growth and success of our research site. This is a partnership opportunity to conduct clinical research with Tilda Research where Tilda will provide Investigators with facilities, staff, systems, and business development.

Duties and Responsibilities:
    • Provide overall medical direction and medical review of protocols in conformance with the investigational plan and good clinical practice.
    • Provide medical and scientific feasibility assessments for all new sponsor inquiries.
    • Ensure that the safety and well-being of all participants in the study at the trial site are protected.
    • Ensure data collected at the study site is credible and accurate.
    • Ensure the rights, integrity, and confidentiality of all participants in the trial at the site are protected.
    • Participate in monitoring visits and sponsor meetings; allow monitoring and auditing by sponsors and inspection by appropriate regulatory agencies.
    • Perform physical assessments and study procedures.
    • Review participants' medical history.
    • Administer Investigational Products.
    • Review and adhere to the study protocol.
    • Be thoroughly familiar with the appropriate use of the investigational product (study drug) as described in the protocol and Investigator's brochure/product monograph and other documents provided by the sponsor.
    • Ensure accuracy, completeness, legibility, and timeliness of data reported on the CRF (case report form) and be consistent with source documents.
    • Ensure participants are informed and receive appropriate therapy and follow-up if the trial is prematurely terminated or suspended for any reason.
    • Immediately report Serious Adverse Events (SAEs) or any abnormalities affecting participants' safety to sponsors and the IRB as per specific reporting guidelines.
    • Maintain proper documentation.
    • Ensure that the study, consent, and other documents provided to the subjects are approved by the IRB and comply with GCP and other regulatory requirements.
    • Maintain trial documents specified by the Essential Documents section of the ICH guidelines and as required by applicable regulatory requirements.
    • Provide access to research-related records to monitors, auditors, representatives of the IRB, and regulatory authorities.

Required Skills and Abilities:
    • Excellent verbal and written communication skills.
    • Excellent organizational skills and attention to detail.
    • Excellent time management skills with a proven ability to meet deadlines.
    • Strong analytical and problem-solving skills.
    • Strong supervisory and leadership skills.
    • Ability to prioritize tasks and delegate them when appropriate.
    • Ability to function well in a high-paced environment.

Education and Experience:
    • Medical degree (MD or DO) with board certification in Internal Medicine or Family Medicine.
    • Active medical license in California.
    • Clinical research experience is required with a minimum of 10 completed studies.

$0 - $350,000 a year

Compensation depends on negotiated rates for each study. The compensation can range from $0 to $350k (or more) annually depending on study volume.

  • Principle Investigator

    4 weeks ago

    Huntington Park, CA, United States Medix™ Full time

    Summary:The Principal Investigator responsibilities are centered around the execution, planning and management of assigned studies. Communicate succinctly with clients, study directors and technicians are key as is a cross-functional, flexible, and collaborative spirit. The Principal Investigator is responsible for the conduct of the clinical trial at a...

  • Incident Investigator, Principal

    2 weeks ago

    Oakland, CA, United States PG&E Corporation Full time

    Requisition ID # 157182  Job Category: Business Operations / Strategy  Job Level: Manager/Principal Business Unit: Operations - Other Work Type: Hybrid Job Location: Oakland; Alameda; Alta; American Canyon; Angels Camp; Antioch; Auberry; Auburn; Avenal; Avila Beach; Bakersfield; Balch Camp; Bear Valley; Belden; Bellota; Belmont; Benicia; Berkeley;...

  • Incident Investigator, Principal

    2 weeks ago

    Oakland, CA, United States PG&E Corporation Full time

    Requisition ID # 157182  Job Category: Business Operations / Strategy  Job Level: Manager/Principal Business Unit: Operations - Other Work Type: Hybrid Job Location: Oakland; Alameda; Alta; American Canyon; Angels Camp; Antioch; Auberry; Auburn; Avenal; Avila Beach; Bakersfield; Balch Camp; Bear Valley; Belden; Bellota; Belmont; Benicia; Berkeley;...

  • Principal Endoscope Architect

    4 hours ago

    San Carlos, CA, United States Noah Medical Full time

    About The Team: Noah Medical's Instruments and Accessories (I&A) Team is responsible for helping identify, define, and explore the front end of endoluminal surgical innovation. The team focuses on generating solutions to address new clinical opportunities, investigates and synergizes technologies, and ultimately delivers proof of concepts that demonstrate...

  • Senior Principal DFT Architect

    1 week ago

    Capitola, CA, United States ARM Full time

    Job Overview:Arm’s Solutions group DFT team implements DFT for SOC for client, datacenter, automotive, and IOT line of business using the latest DFT and process technologies. We closely collaborate with Arm’s partners and internal RTL, Verification, Physical Implementation, and Test engineering teams throughout the life cycle of a project, from an early...

  • Principal Data Solutions Architect

    3 weeks ago

    Oakland, CA, United States PG&E Corporation Full time

    Job Category: Information Technology  Business Unit: Information Technology The Data Solutions Architecture Team at Pacific Gas & Electric Company is responsible for driving long-term, enterprise-wide data solutions, target state architecture, and overall excellence with the application of data, analytics and information to critical business challenges...

  • Principal Data Solutions Architect

    3 weeks ago

    Oakland, CA, United States PG&E Corporation Full time

    Job Category: Information Technology  Business Unit: Information Technology The Data Solutions Architecture Team at Pacific Gas & Electric Company is responsible for driving long-term, enterprise-wide data solutions, target state architecture, and overall excellence with the application of data, analytics and information to critical business challenges...

  • Principal Architect

    1 week ago

    Westlake, TX, United States Fidelity Investments Full time

    Job Description:Fidelity is hiring a Principal Architect – Application Integration (Rest API, Messages, Streaming) at Fidelity Investments.Fidelity Enterprise Architecture – Integration Services Center of Excellence to build and support outstanding products for its highly business critical applications. Our architecture and engineering team is...

  • Principal Data Solutions Architect

    3 weeks ago

    Oakland, CA, United States PG&E Corporation Full time

    Requisition ID # 155115  Job Category: Information Technology  Job Level: Manager/Principal Business Unit: Information Technology Work Type: Hybrid Job Location: Oakland    Department Overview The Data Solutions Architecture Team at Pacific Gas & Electric Company is responsible for driving long-term, enterprise-wide data solutions, target state...

  • Principal Data Solutions Architect

    3 weeks ago

    Oakland, CA, United States PG&E Corporation Full time

    Requisition ID # 155115  Job Category: Information Technology  Job Level: Manager/Principal Business Unit: Information Technology Work Type: Hybrid Job Location: Oakland    Department Overview The Data Solutions Architecture Team at Pacific Gas & Electric Company is responsible for driving long-term, enterprise-wide data solutions, target state...

  • Principal Software Engineer in Test

    3 days ago

    Westlake, TX, United States Fidelity Investments Full time

    Job Description:Principal Software Engineer in Test (Level 6)The TeamThe Fidelity Health Benefits Group supports the recordkeeping and administration of health benefits (medical, dental and vision plans) and life insurance plans on behalf of Fidelity’s corporate clients, their employees and retirees. The technology associates on the FHB Platform team...

  • Research Nurse Coord II

    5 hours ago

    Worcester, MA, United States University of Massachusetts Medical School Full time

    Overview GENERAL SUMMARY OF POSITION: Under the direction of the Principal Investigator or designee, the Research Nurse Coordinator II is responsible to carry out all delegated tasks related to complex protocols testing investigational drugs, devices, or research interventions. The Research Nurse Coordinator II is a primary resource for study protocol...

  • Principal Software Engineer in Test

    5 days ago

    Westlake, TX, United States Fidelity Investments Full time

    Job Description:The Role We are looking for a principal level software engineer in test that takes pride in the craft of building fine software solutions. You will have a strong role to play in the migration of clients from legacy to next-generation healthcare platforms through manual and automated testing. This role is based in Durham, NC. The Expertise...

  • PRINCIPAL ENDOSCOPE ARCHITECT

    6 days ago

    San Carlos, CA 94070, USA, United States Noah Medical Full time

    About The Team:Noah Medical's Instruments and Accessories (I&A) Team is responsible for helping identify, define, and explore the front end of endoluminal surgical innovation. The team focuses on generating solutions to address new clinical opportunities, investigates and synergizes technologies, and ultimately delivers proof of concepts that demonstrate...

  • RESEARCH ASSISTANT I ENDOCRINOLOGY

    4 weeks ago

    , MA, United States Brigham and Women's Hospital Full time

    A research technician position is available in the laboratory of Dr. Eva Liu in the Division of Endocrinology. The laboratory specializes in skeletal biology and investigates the pathophysiology of complications of rare bone disorders and molecular regulation of skeletal processes. Specifically, we have projects focused on osteocyte biology and the molecular...

  • Surety Bond Claims Adjuster

    4 weeks ago

    United States InsuranceStaffing Full time

    Conduct in depth investigation to determine bond liability on construction bond claims. Reviewing all claims related documents, including proofs of loss and supporting documentation. Ensuring timely compliance with statutory and regulatory requirements. Collaborating with team members on claims files. Communicating effectively with principals, claimants and...

  • Clinical Research Associate

    7 days ago

    , CA, United States TalentBurst, Inc. Full time

    Industry: Medical DevicesPosition: Clinical Research Associate with Ophthalmology ExperienceLocation: Remote (However, candidates will need to be in specific states as they may occasionally have to go into the officeDuration: 24 Months ContractNote : 3 days a week at the site. (Travel expense will be reimbursed)Preferred locations: CA- Northern California-...

  • Staff/Principal DFT Engineer

    2 weeks ago

    Cedar Creek, TX, United States ARM Full time

    Job Overview:Arm’s Solutions group DFT team implements DFT for SOC for client, datacenter, automotive, and IOT line of business using the latest DFT and process technologies. We closely collaborate with Arm’s partners and internal RTL, Verification, Physical Implementation, and Test engineering teams throughout the life cycle of a project, from an early...

  • Research Assistant I Endocrinology

    5 hours ago

    Boston, MA, United States Brigham and Women's Hospital Full time

    A research technician position is available in the laboratory of Dr. Eva Liu in the Division of Endocrinology. The laboratory specializes in skeletal biology and investigates the pathophysiology of complications of rare bone disorders and molecular regulation of skeletal processes. Specifically, we have projects focused on osteocyte biology and the molecular...

  • RESEARCH ASSISTANT I ANESTHESIA PAIN MANAGEMENT

    3 weeks ago

    , MA, United States Brigham and Women's Hospital Full time

    GENERAL SUMMARY/ OVERVIEW STATEMENT: Summarize the nature and level of work performed.Working under the general supervision of a Principal Investigator (PI), Clinical Research Assistants will be conducting the study procedures for multiple investigational clinical trials within the field of pain management.PRINCIPAL DUTIES AND RESPONSIBILITIES: Indicate key...