Research Assistant I Endocrinology

3 weeks ago

Boston MA United States Brigham and Women's Hospital Full time

A research technician position is available in the laboratory of Dr. Eva Liu in the Division of Endocrinology. The laboratory specializes in skeletal biology and investigates the pathophysiology of complications of rare bone disorders and molecular regulation of skeletal processes. Specifically, we have projects focused on osteocyte biology and the molecular regulation of the bone-tendon attachment site (enthesis). The technician will be expected to work independently under the general supervision, execute protocols involving variety of routine and non-routine, highly specialized experimental procedures at a professional level. Participates in the design and modification of research protocols under Laboratory Director Supervision. Will be working with research animals and cell culture. Composes and may present sections of research reports, manuscripts or grant application. May have the option of attending research conferences. Performs advanced data analysis using advanced statistical techniques. Coordinates laboratory activities and undertakes quality assurance programs. Will be responsible for orientating and training staff. Will be able to analyze results on her/his own. Technician reports directly to Laboratory Director.

PRINCIPAL DUTIES AND RESPONSIBILITIES:

* Under the Supervision of Principal Investigator, designs and performs research laboratory experiments in the field of bone biology, including:

a. Preparation and analysis of DNA and RNA

b. Molecular biology techniques like RTqPCR

c. Isolation and analysis of proteins including electrophoresis, transfections, etc.

d. Histological studies, including immunohistochemistry

e. Cell culture studies

f. Mouse handling, monitoring and surgical procedures.

* Record data, analyzes and summarizes results. Utilizes computer spread sheets and graphics to prepare data plots and figures.
* Prepares and maintain laboratory reagents, chemicals, instruments, and equipment.
* Maintain supplies and inventory, and maintain established departmental policies, procedures, objectives, quality assurance, safety, environmental and infection control.
* Assist in the training of new lab members.
* Discusses program, regularly with Principal Investigator.
* Performs other duties and responsibilities as directed.

BS OR BA

New graduate with relevant course or project work

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