Principal Scientist, Potency, Functional Biocharacterization and Impurities

2 weeks ago

REDMOND OR, United States Evotec Group Full time

Just- Evotec Biologics is seeking a motivated and creative principal scientist who desires a significant opportunity to improve worldwide access to biotherapeutics. The candidate will join a fast-paced, collaborative, and multidisciplinary team to develop and execute methods for the functional and potency assessment and impurity monitoring of biotherapeutics.  As a key member of the analytical development group, the successful candidate will have significant experience in immunoassay and qPCR method development and qualification/validation, as well as strong experimental design and data analysis skills. Previous experience in late-stage and first-in-human (FIH) development, participation in CMC teams, and experience authoring regulatory documents is required. This person would be taking on a leadership role in immunoassay, and should have significant experience and understanding in ELISAs, Octet/BLI, AlphaLISA, and Biacore/SPR methods. The ideal candidate has strong written and verbal communication skill, multitasks effectively, works well independently and in teams, and is excited about ways to improve technology. The candidate will also be involved in leading cross-functional initiatives and supervising direct reports, and would be in a role that interfaces directly with clients on projects specifically related to immunoassay and impurities.Responsibilities:Characterization of early and late stage biotherapeutics using diverse biological assay formatsLead and implement method development, DOE robustness, and qualification activitiesTechnology transfer to Just- Evotec’s Quality Control laboratoryParticipation in process development team(s), including potential for acting as analytical team lead and interfacing both internally and externally to clientsTechnology development to improve throughput and efficiencyAuthor and contribute to documents to support regulatory filings (including IND, INDa, BLA, IMPD)Mentor and train junior staff Present data to a wide range of audiences, including internal technical development teams, clients, industry conferences, and peer-reviewed journalsLead immunoassay and kinetic assay (BLI/Octet, Biacore/SPR) efforts for the groupLead cross-functional teams and initiativesSupervise and develop the careers for 1-2 direct reports​Required Qualifications:BS/MS in Biochemistry, Biology, Bioengineering or related field with 15+ years of experience or Ph.D. with 6+years of experience.Experience developing analytical methods in a CMC or GMP-like industry settingExcellent understanding of ICH/USP guidelines on analytical, impurity, and potency assay development and validationExperience in the development, DOE robustness, and qualification and/or validation of release potency and impurity methods (immunoassays and qPCR)Strong technical understanding of link between MOA and analytical method development, and effects of impurities on biological manufacturing processesExperience in areas of technology development pertinent to impurities and potency assay development, including but not limited to assay automation and miniaturization and monitoring and characterization of diverse HCP’sExperience developing and applying biological characterization methods (e.g. cell-based assays, SPR/BLI or other protein binding kinetic assays, immunoassays, homogeneous assay formats such as AlphaLISA)Strong oral and written communication skillsDesire to work in a fast, collaborative, and team-oriented environmentPreferred Qualifications:Experience utilizing industry-standard analysis software (e.g. SoftMax Pro, JMP)Development of liquid-handling automation applicationsExperience with early & late stage regulatory filings Experience in technology transferExperience participating in CMC teamsThe base pay range for this position at commencement of employment is expected to be $140,000 to $170,000;  Base salary offered may vary depending on individual’s skills, experience and competitive market value. Additional total rewards include discretionary annual bonus, comprehensive benefits to include Medical, Dental and Vision and 401k company match, flexible paid time off and paid holiday, wellness and transportation benefits. Evotec (US) Inc. is an Equal Opportunity Employer.  All qualified applicants will receive consideration for employment without regard to race, gender, age, disability, genetic information, gender expression, gender identity, national origin, religion, sexual orientation, or veteran status.SummaryLocation: Redmond; SeattleType: Full time

  • Scientist II, Potency and Impurities

    4 weeks ago

    Redmond, United States Evotec Full time

    Just- Evotec Biologics is seeking a motivated and creative Scientist II who desires a significant opportunity to improve worldwide access to biotherapeutics. The candidate will join a fast-paced, collaborative, and multidisciplinary team to develop and execute methods for the functional and potency assessment and impurity monitoring of biotherapeutics. As...

  • Associate Scientist, Potency and Impurities

    2 weeks ago

    Redmond, United States Just - Evotec Biologics Full time

    $48,510$90,090Just-Evotec Biologics is seeking a motivated and creative Associate Scientist who desires an opportunity to improve worldwide access to biotherapeutics. You will have the opportunity to collaborate with a multidisciplinary team develop and execute methods for the potency assessment and impurity monitoring of biotherapeutics. As a key member of...

  • Principal Scientist, Purification Process Development

    2 weeks ago

    REDMOND, OR, United States Evotec Group Full time

    Principal Scientist, Purification | Just-Evotec, Redmond, WA | Just is seeking a motivated and creative scientist or engineer who desires a significant opportunity to improve worldwide access to biotherapeutics. As a downstream design scientist/engineer, you will join a fast-paced, collaborative, and multidisciplinary team to develop purification processes...

  • Principal Data Scientist

    2 weeks ago

    Redmond, United States DevSelect Full time

    Our Client is looking for Data Scientists who are dedicated to data mining techniques for various applications serving enterprise and consumer end-users. Understanding of machine learning techniques including predictive modeling, text and image mining, clustering, deep learning, anomaly detection, forecasting methods and other advanced statistical...

  • Data Scientist

    2 weeks ago

    Redmond, United States Talent Software Services Full time

    Data Scientist Job Summary: Talent Software Services is in search of a Data Scientist for a contract position in Redmond, WA. Opportunity will be one year with a strong chance for a longterm extension. Position Summary: The main function of a Data Scientist is to coordinate changes to computer databases, test, and implement the database applying knowledge of...

  • Scientist/Senior Scientist Protein Engineering

    1 week ago

    Redmond, United States SystImmune Full time

    Located in Redmond WA, Systimmune Inc. is a clinical-stage bio-pharmaceutical company focused on the treatment of cancer through developing breakthrough-therapeutic multi-specific antibodies, as well as antibody-drug conjugates (ADCs). Currently, the company has eight assets in ongoing clinical trials and a robust preclinical pipeline of therapeutics from...

  • Scientist/Senior Scientist Protein Engineering

    4 weeks ago

    Redmond, United States SystImmune Full time

    Located in Redmond WA, Systimmune Inc. is a clinical-stage bio-pharmaceutical company focused on the treatment of cancer through developing breakthrough-therapeutic multi-specific antibodies, as well as antibody-drug conjugates (ADCs). Currently, the company has eight assets in ongoing clinical trials and a robust preclinical pipeline of therapeutics from...

  • Scientist/Senior Scientist Protein Engineering

    4 weeks ago

    Redmond, United States SystImmune Full time

    Located in Redmond WA, Systimmune Inc. is a clinical-stage bio-pharmaceutical company focused on the treatment of cancer through developing breakthrough-therapeutic multi-specific antibodies, as well as antibody-drug conjugates (ADCs). Currently, the company has eight assets in ongoing clinical trials and a robust preclinical pipeline of therapeutics from...

  • Medical Lab Scientist/MLT

    2 weeks ago

    Redmond, United States St. Charles Health System Full time

    MLS Typical pay range: $35.73- $53.60 MLT Typical pay range: $28.37- $42.55 Schedule: Variable Days, and Variable Hours Differentials: Float Differential: $5/hr. Evening Shift: $2.50/hr. Night Shift: $6.50/hr. Weekend Shift: $4.00/hr. ST. CHARLES HEALTH SYSTEM JOB DESCRIPTION TITLE: Medical Laboratory Scientist (MLS) REPORTS TO POSITION:...

  • Director, Drug Product Design

    1 week ago

    REDMOND, OR, United States Evotec Group Full time

    Director of Drug Product Development | Process and Product Design, Redmond WAJust-Evotec Biologics is looking for a Director of Drug Product Development to join a fast-paced, collaborative, and multidisciplinary team to lead all aspects of drug product development for the advancement of low-cost biotherapeutics manufacturing. The Director is responsible for...

  • Principal IS Supply Chain Service Engineer

    1 week ago

    Redmond, United States Providence St. Joseph Health Full time

    Description Principal IS Supply Chain Service Engineer supports the Supply Chain process for caregiver devices and peripherals, including obtaining quotes, all warranty repairs, replacements and loaner device distribution. Leverages ServiceNow and Oracle to obtain source of truth information. Serves as the primary point of support to resolve incidents and...

  • Principal IS Supply Chain Service Engineer

    1 week ago

    Redmond, United States Providence St. Joseph Health Full time

    Description Principal IS Supply Chain Service Engineer supports the Supply Chain process for caregiver devices and peripherals, including obtaining quotes, all warranty repairs, replacements and loaner device distribution. Leverages ServiceNow and Oracle to obtain source of truth information. Serves as the primary point of support to resolve incidents and...

  • Mgr, Manufacturing Operations

    3 weeks ago

    Redmond, United States Evotec SE Full time

    Manager, Manufacturing Operations - Purification | Redmond, WA This position will responsible for supervising a shift to cover 24/7 operation and requires significant on-the-floor presence, as well as technical subject matter expertise in purification operations.? Additional job responsibilities will include generation and maintenance of cGMP manufacturing...

  • Data Scientist

    2 weeks ago

    Redmond, United States Omni Inclusive Full time

    STRONG PYTHON and LLM experience Responsibilities: Design, develop, and implement Gen AI models for various applications, focusing on tasks like data augmentation, anomaly detection, and content generation. Collaborate with engineers to integrate Gen AI models into existing systems and workflows utilizing AKS, Cosmos DB, and Synapse Analytics. Participate in...

  • Enterprise Architect

    2 weeks ago

    Redmond, United States DevSelect Full time

    Title:  Enterprise Architect Duration: FTE Location: Redmond WA,   JOB DESCRIPTION: Enterprise Architect is responsible for defining, upholding, and communicating the vision of the IT architecture and solutions that support the business strategies.  This individual provides architectural leadership, consensus driven decision process, technology,...

  • Optical Engineer

    3 weeks ago

    Redmond, United States META Full time

    At Meta's Reality Labs Research, our goal is to make world-class consumer virtual, augmented, and mixed reality experiences. Come work alongside industry-leading scientists and engineers to create the technology that makes VR and AR pervasive and universal. Join the adventure of a lifetime as we make science fiction real and change the world. We are looking...

  • Director, Drug Product Design

    6 days ago

    Redmond, United States Evotec SE Full time

    Director of Drug Product Development | Process and Product Design, Redmond WA Just-Evotec Biologics is looking for a Director of Drug Product Development to join a fast-paced, collaborative, and multidisciplinary team to lead all aspects of drug product development for the advancement of low-cost biotherapeutics manufacturing. The Director is responsible...

  • Senior Director, Protein Engineering

    4 weeks ago

    Redmond, United States SystImmune Full time

    Located in Redmond WA, Systimmune Inc. is a bio-pharmaceutical company focused on the treatment of cancer through developing novel therapeutic multi-specific antibodies, as well as antibody-drug conjugates (ADCs). Our objective is to create biologics that work through systematic intervention on the solid tumor micro-environment, to either directly attack the...

  • Senior Director, Protein Engineering

    4 weeks ago

    Redmond, United States SystImmune Full time

    Located in Redmond WA, Systimmune Inc. is a bio-pharmaceutical company focused on the treatment of cancer through developing novel therapeutic multi-specific antibodies, as well as antibody-drug conjugates (ADCs). Our objective is to create biologics that work through systematic intervention on the solid tumor micro-environment, to either directly attack the...

  • Prototyper V

    2 weeks ago

    Redmond, United States Ursus Inc Full time

    JOB TITLE: Prototyper V - AI/Client LOCATION: Onsite in Redmond, WA DURATION: 6 months PAY RANGE: $75-85/Hour TOP 3 SKILLS: Minimum of 5 years in Prototyping or Game Development t least 2 years of research experience in AI/Client Prototyping Experience building prototypes within short time frames COMPANY: Our client is a Fortune 500 multi-national...