ASSOCIATE DIRECTOR/DIRECTOR, PLATFORM BIOLOGY

2 weeks ago

Oakland CA USA, United States Totus Medicines Full time
Totus Medicines is an innovative therapeutic drug discovery biotech that has developed a platform focused on targeted covalent drugs. This novel proprietary platform will enable Totus to deliver candidates against challenging targets in months, not years - 100,000 times faster than competitive technologies and has the potential to expand the spectrum of drug targets to be screened for any disease process.

Totus discovered its first-in-class covalent program in 4 months and entered Phase I in 2023. Totus also plans to expand their platform to create therapeutics targeted at neurodegeneration, infectious diseases, and others. We are searching for talented, passionate, agile candidates to join our team.

This broadly impactful role will report to the Head of Platform and manage a team providing leadership in the selection, assessment, and preparation of targets for phenotypic DEL screening using the Totus Discovery Platform. The Platform Biology team will also lead efforts to confirm, validate, and characterize resulting small molecule hit compounds engaging protein targets of interest in addressing multiple disease areas.

Responsibilities:

* Provide leadership and oversight to the Platform Biology team; partner with adjacent function leaders to ensure the successful execution of chemical library screens. This will cover internal Totus campaigns, as well as those conducted with partner organizations.
* Oversee the engineering and generation of protein reagents vital for executing successful screens.
* Develop capabilities and expertise to support the confirmation and characterization of covalent and non-covalent small molecule hits in biochemical, biophysical, and cellular assays.
* Provide ongoing coaching and mentorship in target biology and preclinical compound characterization and ensure sufficient expertise to support the organization.
* In partnership with other key stakeholders on the Totus Platform team, continue to develop and evolve the platform technology to incorporate new chemical, biological, and technical capabilities.
* Keep pace with technology industry trends and implications for the business.

What You Will Bring:

* PhD in chemical biology, biophysics, enzymology, or a related field.
* 5+ (AD) or 10+ (director) years of experience developing, implementing, and executing characterization assays supporting small molecule drug discovery.
* 2+ (AD) or 5+ (director) years of relevant management experience.
* Proven track-record of leadership and achievement in drug discovery; familiarity with DNA-encoded library screening would be highly beneficial.
* Ability and desire to work in a fast-paced, hard-working, multi-disciplinary, start-up environment.
* Excellent organizational skills and ability to prioritize and deliver results.
* Excellent communication and influencing skills and a desire to work collaboratively and lead in a matrix environment.
* Familiarity with oncology, metabolic disease, inflammation, or neurodegenerative disease drug discovery is highly desirable.

Compensation Range:

Associate Director: $150,600 - $194,200

Director: $189,000 - $243,800

  • Associate Director of Assessment and Evaluation

    4 days ago

    Oakland, United States University of California , Riverside Full time

    Working under the supervision of the Associate Dean for Assessment and Evaluation, the Associate Director of Assessment and Evaluation manages critical processes related to the UCR School of Medicine's program evaluation and student performance assessment procedures. The incumbent will share primary responsibilities for program evaluation and student...

  • Associate Director of College Counseling

    3 weeks ago

    Oakland, United States The College Preparatory School Full time

    The College Preparatory School Associate Director of College Counseling Location: Oakland, California July 2024 Position Overview: The College Preparatory School, an independent high school in Oakland, California, seeks a talented and dynamic individual to serve as the Associate Director of College Counseling. This is a full-time position. The person in this...

  • Associate Director, Data Science

    3 weeks ago

    Oakland, United States Material Holdings, LLC Full time

    Associate Director, Data Science Company: Material Holdings, LLC Location: Oakland, CA Position Type: Full Time Experience: See below Education: See below Data mining to support CRM, Loyalty Program performance & custom clickstream projects. Extract,....

  • Director, Platform Engineering

    3 days ago

    San Jose, CA, United States Balbix, Inc. Full time

    ENGINEERING Balbix, Inc. in San Jose, CA seeks Director, Platform Engineering & ML Operations: Design & architect solutions for the data engineering pipeline. Work with the Chief Technology Officer to ensure product architecture for new features or enhancements is consistent and correct. $239,200/yr. - $249,200/yr. Email res (must reference Job Code #42375)...

  • Director of Communications

    1 month ago

    Oakland, United States Michigan Association of School Boards Full time

    **Deadline**:April 26, 2024 **District/Organization**:Oxford Community Schools **Position/Type**:Communications, full time **Salary**:Starting at $91,114 **Position Details**: **April 5, 2024 **Internal/External Posting **Primary Function**:The Director of Communications will set, guide, and execute the strategy for all communications, website, and public...

  • Human Resource Director

    6 days ago

    Oakland, United States Oakland School for the Arts Full time

    Human Resources Director Job Description May 2024 Oakland School for the Arts (OSA) is seeking an experienced Human Resources Director to join our outstanding team. Under the leadership of the Executive Director, the Human Resources Director is responsible for the overall administration, coordination and performance of human resource functions supporting...

  • Human Resource Director

    4 days ago

    Oakland, United States Oakland School For The Arts Full time

    Human Resources Director Job Description May 2024 Oakland School for the Arts (OSA) is seeking an experienced Human Resources Director to join our outstanding team. Under the leadership of the Executive Director, the Human Resources Director is responsible for the overall administration, coordination and performance of human resource functions supporting...

  • Director of Finance

    6 days ago

    Oakland, United States Castle Rock Consulting Full time

    Are you an experienced non-profit CFO,Finance Director, or Controller who wants to use your expertise in a flexible, part-time capacity? This may be the ideal role for you! We are seeking qualified Finance Directors with nonprofit experience to join our team for long-term, part-time engagements with our nonprofit clients. Flexible scheduling, from 10-40...

  • Associate Director, Alumni Relations and Communications

    2 weeks ago

    Los Angeles, CA - University Park Campus, United States Gould School of Law Full time

    Founded in 1896, the Gould School of Law has a distinguished past built on the principles of equity and excellence, and the courage to break new ground. USC first introduced legal education in Southern California. Today, the Law School continues to make history through its philosophy of innovation and through its people. USC Gould cultivates analytical...

  • Assistant Director of Nursing

    2 weeks ago

    Oakland, United States Gulf Stream Staffing Full time

    Gulfstream Staffing is partnered with a nationally recognized Mental Health organization that has decades of experience and stability. We are currently seeking candidates for a full-time Assistant Director of Nursing (ADON) opportunity near Oakland, CA. This organization has a leadership team of visionaries among the best in the business and a focus on a...

  • Director of Finance

    4 weeks ago

    Oakland, United States Castlerock Consulting Full time

    Job DescriptionJob DescriptionAre you an experienced non-profit CFO, Finance Director, or Controller who wants to use your expertise in a flexible, part-time capacity? This may be the ideal role for you!   We are seeking qualified Finance Directors with nonprofit experience to join our team for long-term, part-time engagements with our nonprofit...

  • Assistant Director

    3 weeks ago

    Oakland, United States Veterans Benefits Administration Full time

    Summary The incumbent serves as the Assistant Director for the Oakland Regional Benefits Office. As Asst. Director, shares fully with the Director responsibility for the effective, efficient, and economical direction, control, and operation of the VBA's program of benefits & services provided by law for veterans, their dependents, and beneficiaries,...

  • Director of Data

    4 days ago

    Oakland, United States LaunchDarkly Full time

    LaunchDarkly is seeking an experienced Director of Data to lead our Data Analytics and Insights function. You will manage our existing team of Analytics Engineers, shape our data platform, define the team's mission, vision, and operating model, and hire as needed to flesh out the team. You will guide the growth of the data organization as we scale beyond a...

  • Nurse Director of Surgical Services

    2 weeks ago

    Oakland, United States Clinical Management Consultants Full time

    A new opportunity located in California's Bay Area has just become available for a Director of Surgical Services! A prestigious non-profit health system in Northern California is seeking a highly qualified and experienced Nurse Director of Surgical S Director, Surgical, Nurse, Service, Healthcare, Staffing

  • Director, Environmental Engineering

    3 weeks ago

    Oakland, United States Emissary Recruiting Solutions, Inc. Full time

    Director of Environmental Engineering Services (PE) or (PG) Location: Oakland, CA (with substantial presence/activities throughout Northern/Central CA. Overview: Our Client is a California-based consulting firm providing technical, efficient and cost-effective solutions to our clients' Industrial Hygiene, Regulatory Compliance and Environmental Engineering...

  • Director of Finance

    2 weeks ago

    Oakland, United States Siino & Associates LLC Full time

    Job DescriptionJob DescriptionOur client, a nonprofit organization located in San Francisco, CA, is looking for its first Director of Finance to be responsible to plan, manage and control the financial activities of the organization. The position reports to the CEO. On-going tasks will include managing the processes of general accounting, budget and...

  • Director of Community Day Supports

    1 week ago

    Oakland, United States East Bay Innovations Full time

    The Community Day Supports Director is responsible for overseeing the orientation, planning, recruitment, training, and supervision of staff within the Community Day Supports (CDS) program. This role ensures that services provided align with the valu Director, Support, Staff, Technology, Training

  • Summer Aftercare Assistant Director

    4 days ago

    Oakland, United States Hip Wah Summer Program Full time

    The Aftercare Assistant Director supports the Arftercare Director with the day to day running of camp through Aftercare. You will ensure that campers are fed, supervised, arriving to their correct classes and locations, signed in and out, and picked up. This role also includes supervising assistants to ensure they engage with campers, create enrichment...

  • Director of Facilities and Operations

    23 hours ago

    Oakland, United States Michigan Association of School Boards Full time

    **Deadline**:May 31, 2024 **District/Organization**:Birmingham Public Schools **Position/Type**:Other, full time **Salary**:$98,158 - $128,264 **Position Details**: Birmingham Public Schools is seeking a Director of Facilities and Operations for the 2024-25 school year.

  • Director of Sales and Marketing

    4 days ago

    Oakland, California, United States Front Porch Communities and Services Full time

    Position Title: Director of Sales and Marketing Job ID: 2792 Community: St. Paul's Towers Location: US:CA:Oakland Category: Work Type: Full Time Salaried Date Posted: 5/2/2024 Salary: USD per hour DescriptionJOB SUMMARY Under the direction of the Executive Director, our Director of Sales and Marketing plays a pivotal role in the growth of our organization....