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Postdoctoral Researcher

1 month ago


Boston, United States Beth Israel Deaconess Medical Center Full time

Postdoctoral fellow position to study the mechanisms of metastatic colonization


The Piskounova lab at Beth Israel Deaconess Medical Center has an available position to hire a highly motivated, creative, and enthusiastic postdoctoral fellow. Located in the Cancer Center at BIDMC, the Piskounova Lab investigates molecular mechanisms that enable metastatic colonization, with particular focus on translational regulation of stress resistance. To address this question, we use multidisciplinary approaches including biochemistry and cell biology in the context of patient-derived and mouse models of melanoma metastasis.


Position Summary


Applicants should have recently completed their graduate degree (PhD or MD/PhD) with a background in biochemistry, and/or molecular and cellular biology. The successful candidate will lead projects to investigate the role of tRNA modifications and/or the Integrated Stress Response in regulating translation in metastasizing melanoma cells. The primary responsibility will be to design and perform benchwork independently and publish results in international meeting and peer-reviewed journals. In addition, the successful candidate will be encouraged to develop their own research ideas along the lines of the research interest of the lab. You will join a vibrant and fun lab environment and be part of a multidisciplinary team in a stimulating academic setting, with plenty of resources for intellectual and career development, as well as strong mentoring.


Principal Responsibilities


Key responsibilities of this role include, but are not limited to:

·      Independently design, develop and test biological hypotheses.

·      Interrogate novel cellular and molecular biology.

·      Work independently to execute hands-on experiments and analyze data.

·      Publish research findings in top-tier publications.

·      Effectively present data in internal and external meetings.

·      Drive multiple exploratory projects, and work collaboratively with research associate and graduate students.


Education and Qualifications Required


·      Recent Ph.D. in molecular and cell biology, biochemistry, oncology, or a related field.

·      Strong track record demonstrated in the context of mechanistic studies using molecular and cellular biology techniques reflected in a strong record of achievement in peer-reviewed publications (i.e., at least one first author publication).

·      Strong hands-on expertise and solid skills in molecular/cell biology and biochemistry.

·      Ability to work in a team environment, excellent data handling and recording skills as well as oral and written communication skills.

·      Ability of trouble shooting and data analysis.


Preferred


• Prior mouse handling experience and flow cytometry knowledge.


Candidates should provide a cover letter and a CV to episkoun@bidmc.harvard.edu