JOB POSTING: Bioinformatics Scientist

2 weeks ago


Frisco, United States Ayass BioScience, LLC Full time

Ayass Bioscience and Ayass Laboratory are seeking a talented Bioinformatics Scientist as a consultant/full time employee to join our team analyzing complex gene expression datasets. You will work cross-functionally to derive insights from large-scale transcriptomics data across various disease models by building specialized analysis pipelines, machine learning models, and pathway annotations.

Requirements:

  • PhD with 5+ years experience in RNA-seq analysis and transcriptome profiling
  • Expertise in differential expression analysis, gene set enrichment, genomic pattern recognition
  • Proficiency building pipeline workflows, ML models, interactive visualizations in R/Bioconductor
  • Experience linking transcriptomic signatures to drug response, clinical outcomes data
  • Knowledge of pathway databases for functional enrichment integration
  • Excellent communication skills to convey complex multi-omic findings

Your responsibilities will include:

  • Analyzing high-throughput transcriptomic sequencing data from various biological systems
  • Interpreting differential expression patterns and co-expression networks
  • Developing transcriptomics-based biomarkers using machine learning techniques
  • Working with ML engineers to integrate multi-omic data into predictive models of disease progression and therapeutic response
  • Linking mechanistic pathway analysis with pharmacology models
  • Annotating genes and variants with the latest knowledge on disease ontologies
  • Visualizing multi-omic datasets to uncover genotype-phenotype relationships
  • Continually refining methodology as new insights into disease emerge
  • Presenting techniques and results to diverse audiences

This opportunity leverages massive datasets to unravel molecular mechanisms of disease. You will translate cutting-edge bioinformatics into bold new therapeutics, while accelerating your expertise in multi-omic data integration.



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