Research Technologist
2 weeks ago
We are seeking a Research Technologist who will follow protocols and procedures to perform general laboratory duties and techniques. 50% of the time will be spent learning biochemical techniques, including cell culture, enzyme activity assays, RT-PCR, western blot, and immunohistochemistry. The remaining 50% of the time will be spent performing animal models of peripheral nerve crush and aging.
Specific Duties & Responsibilities
- Grow and maintain astrocytoma (CCF-STTG1) cells; conduct high-throughput screening of Rapafucin and Life Chemicals‘ CNS-focused libraries targeting System xc- in STTG1 cells for glioblastoma and age-related degenerative diseases in the central nervous system.
- Assist with evaluating glutamate carboxypeptidase II (GCPII) as a therapeutic target in peripheral nerve degeneration and the function of Schwann cells in aging.
- Study efficacy and pharmacokinetic properties of potential treatments using mouse models of peripheral nerve crush and aging.
- Maintain aged mouse colonies, including breeding, genotyping, and treating animals.
- Assist postdoctoral fellow in behavioral and electrophysiological assessments of aging mouse models.
- Assist in performing histological assessments of therapeutic efficacy in peripheral nerve crush and aging mouse models, including tissue collection, sectioning, and immunohistochemical staining.
- Perform miscellaneous related duties as assigned.
Minimum Qualifications
- Bachelor‘s Degree in Biology, Chemistry or related field.
- Some related post-undergraduate mouse model work experience preferred.
Classified Title: Research Technologist
Role/Level/Range: ACRO40/E/02/CC
Starting Salary Range: $15.50 - $26.00 HRLY ($40,000 targeted; Commensurate with experience)
Employee group: Full Time
Schedule: M-F, 8:30-5pm
Exempt Status:Non-Exempt
Location:School of Medicine Campus
Department name: BSi NeuroTranslational Program
Personnel area: School of Medicine
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