Scientist, In Vivo Biology

2 weeks ago

Cambridge, United States GC Therapeutics Full time

Company Overview


GC Therapeutics is the first genome-wide cell landscape exploration company using an integrated synthetic biology and AI-driven platform for cell programming. Its patent-pending and proprietary pluripotent stem cell differentiation technology platform TFome™ was developed in Professor George Church’s lab, a pioneer in synthetic biology, and allows for the development of unique cell therapies with significantly streamlined manufacturing, improved cell quality, efficiency and speed. GC Therapeutics is based in Cambridge, MA. For additional information, please visit


Job Purpose


GC Therapeutics is seeking a talented and highly motivated Scientist to join our in-vivo team. This role will involve bringing a new class of cellular therapies to patients using GCTx’s Human TFome™ platform, a synthetic biology-driven technology to differentiate human stem cells. The ideal candidate will have strong expertise in designing, executing, and analyzing in vivo studies using animal models of disease. Thiscandidate will be involved in all aspects of our experiments to assess GCTx’s cell therapies in small animal models.


Duties and Responsibilities


General Laboratory Roles:


· Responsible for experimental design, data generation, analysis, and communication of results to supervisor and team members.

· Maintain a detailed laboratory journal, summarize results, and create presentations for internal group meetings.

· Exemplify scientific curiosity and deep expertise with relevant literature and cutting-edge technologies to advance research directions.

· Work with other members of the research team and within GCTx to accomplish company goals.

· Follow all safe laboratory practices and company policies.


Specific Responsibilities:


· Design and execute experiments to evaluate GCTx’s cell therapies in preclinical animal models of disease.

· Keep accurate and detailed records of animal care.

· Follow IACUC protocol and all other animal care compliance regulations.

· Perform biochemical and histological assays on tissue samples from preclinical studies.

· Analyze data from in vivo studies and report findings to the company.


Qualifications


Essential Qualifications:


· Ph.D. degree in stem cell biology, cell biology, bioengineering, biochemistry, or related discipline and 3 years of laboratory work experience in academia or industry.

· Required expertise in rodent handling and surgeries, including hands-on experience with injecting or transplanting cells into rodents.

· Experience in immunohistochemistry, histology, and image analysis.

· Strong work ethic with the ability to perform tasks independently.

· Proficient in analysis, presentation, and documentation of scientific data as well as preparation of scientific reports.

· Effective communicator with excellent interpersonal skills.

· Strong project management and organizational skills and ability to prioritize and multitask.


Additional Preferred Qualifications:

· Experience with cell culture (e.g. hiPSCs, primary cells)

· Practical familiarity with stem cell differentiation protocols.

· Proven track record and strong publications in cell biology and animal work.



Equal Opportunity Workplace: GC Therapeutics is an equal opportunity employer. We provide equal employment opportunities to all applicants for employment and existing employees without regard to ancestry, national origin, place of birth, race, color, gender, sexual orientation, marital status, pregnancy, religion, age, disability, gender identity, results of genetic testing, service in the military or otherwise to the full extent of all federal, state and local laws. GC Therapeutics’ equal employment opportunity policy applies to all terms and conditions of recruiting, hiring, placement, training, compensation, transfer, leave of absence, employment, promotion, layoff and termination of employment.

  • Scientist, In Vivo Biology

    2 weeks ago

    Cambridge, United States GC Therapeutics Full time

    Company Overview GC Therapeutics is the first genome-wide cell landscape exploration company using an integrated synthetic biology and AI-driven platform for cell programming. Its patent-pending and proprietary pluripotent stem cell differentiation technology platform TFome™ was developed in Professor George Church’s lab, a pioneer in synthetic biology,...

  • Scientist, In Vivo Biology

    3 weeks ago

    Cambridge, United States GC Therapeutics Full time

    Company Overview GC Therapeutics is the first genome-wide cell landscape exploration company using an integrated synthetic biology and AI-driven platform for cell programming. Its patent-pending and proprietary pluripotent stem cell differentiation technology platform TFome™ was developed in Professor George Church’s lab, a pioneer in synthetic biology,...

  • Scientist, Translational In Vivo Sciences

    5 days ago

    Cambridge, Massachusetts, United States Biogen Full time

    Job Description About This Role Translational In Vivo Sciences is seeking a scientist to join a cross-functional research effort to enhance the delivery of Biogen’s therapeutics to the central nervous system (CNS) and muscle. These efforts will be applied across multiple therapeutic areas in the neurological and neuromuscular space, supporting portfolio...

  • Associate In Vivo Scientist

    3 weeks ago

    Cambridge, Massachusetts, United States Eli Lilly and Company Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...

  • Sr. Research Associate

    4 days ago

    Cambridge, United States Fulcrum Therapeutics, Inc. Full time

    Company Overview Fulcrum Therapeutics is a clinical-stage biopharmaceutical company focused on improving the lives of patients with genetically defined rare diseases in areas of high unmet medical need. Fulcrum's two lead programs in clinical development are losmapimod, a small molecule for the treatment of facioscapulohumeral muscular dystrophy (FSHD) and...

  • Sr. Research Associate

    3 days ago

    Cambridge, United States Third Rock Ventures Full time

    Fulcrum Therapeutics is a clinical-stage biopharmaceutical company focused on improving the lives of patients with genetically defined rare diseases in areas of high unmet medical need. Fulcrum's two lead programs in clinical development are losmapimod, a small molecule for the treatment of facioscapulohumeral muscular dystrophy (FSHD) and pociredir, a small...

  • Associate In Vivo Scientist

    3 weeks ago

    Cambridge, United States Eli Lilly and Company Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...

  • Scientist, Biology

    3 days ago

    Cambridge, United States Third Rock Ventures Full time

    The Opportunity: Our creative, collaborative, and talented biology group is looking for a strong addition to our team. The ideal candidate will combine a deep understanding of cellular and molecular biology with experience in drug discovery to help drive one of our newest projects from early stages to clinical development. You will contribute to the biology...

  • Scientist, Biology

    4 days ago

    Cambridge, United States Relay Therapeutics, Inc. Full time

    The Opportunity: Our creative, collaborative, and talented biology group is looking for a strong addition to our team. The ideal candidate will combine a deep understanding of cellular and molecular biology with experience in drug discovery to help drive one of our newest projects from early stages to clinical development. You will contribute to the biology...

  • Sr. Scientist II, In Vivo Therapeutics Discovery

    2 weeks ago

    Cambridge, United States Editas Medicine Full time

    At Editas, we’re driven by a collective purpose, to bring transformative and life changing therapies to people living with serious diseases with the greatest unmet needs. This fuels our drive to excel in scientific innovation, allowing us to harness the power and potential of CRISPR/Cas9 and CRISPR/Cpf1 (Cas12a) gene editing.We believe our people are at...

  • Sr. Scientist II, In Vivo Therapeutics Discovery

    2 days ago

    Cambridge, United States Editas Medicine Full time

    Job DescriptionJob DescriptionAt Editas, we’re driven by a collective purpose, to bring transformative and life changing therapies to people living with serious diseases with the greatest unmet needs. This fuels our drive to excel in scientific innovation, allowing us to harness the power and potential of CRISPR/Cas9 and CRISPR/Cpf1 (Cas12a) gene...

  • Sr. Scientist II, In Vivo Therapeutics Discovery

    2 weeks ago

    Cambridge, United States Editas Medicine Full time

    Job DescriptionJob DescriptionAt Editas, we’re driven by a collective purpose, to bring transformative and life changing therapies to people living with serious diseases with the greatest unmet needs. This fuels our drive to excel in scientific innovation, allowing us to harness the power and potential of CRISPR/Cas9 and CRISPR/Cpf1 (Cas12a) gene...

  • Scientist I/II

    3 weeks ago

    Cambridge, United States UCB Full time

     Make your mark for patients We are currently seeking a highly skilled and motivated Scientist I/II with expertise in molecular and cellular biology to join our Discovery Biology team. The candidate will be expected to design, execute and analyze in vivo experiments to validate gene therapy targets for the treatment of genetic diseases. This is a...

  • Director, Biology

    4 days ago

    Cambridge, United States Delphia Full time

    About Us:Delphia is igniting a new field of therapeutics in hopes to transform the care of cancer patients. Together, we are working to advance first-in-class targeted cancer medicines leveraging Activation Lethality, a new field of cancer biology centered on cancer’s surprising vulnerability to oncogene overactivation. While a bold idea, activation...

  • Scientist I/II

    3 weeks ago

    Cambridge, United States UCB Full time

     Make your mark for patients We are currently seeking a highly skilled and motivated Scientist I/II with expertise in molecular and cellular biology to join our Discovery Biology team. The candidate will be expected to design, execute and analyze in vivo experiments to validate gene therapy targets for the treatment of genetic diseases. This is a...

  • Sr. Scientist II, In Vivo Therapeutics Discovery

    2 weeks ago

    Cambridge, Massachusetts, United States Editas Medicine Full time

    At Editas, we’re driven by a collective purpose, to bring transformative and life changing therapies to people living with serious diseases with the greatest unmet needs. This fuels our drive to excel in scientific innovation, allowing us to harness the power and potential of CRISPR/Cas9 and CRISPR/Cpf1 (Cas12a) gene editing. We believe our people are at...

  • SCIENTIST, BIOLOGY

    5 days ago

    Cambridge, MA 02138, USA, United States Relay Therapeutics, Inc. Full time

    The Opportunity:Our creative, collaborative, and talented biology group is looking for a strong addition to our team. The ideal candidate will combine a deep understanding of cellular and molecular biology with experience in drug discovery to help drive one of our newest projects from early stages to clinical development. You will contribute to the biology...

  • Principal Research Associate/Scientist, Immunology

    3 days ago

    Cambridge, United States Orbital Therapeutics Full time

    Position Summary: Orbital Therapeutics is currently seeking a highly motivated, self-driven, collaborative and creative individual with experience in immunology, looking to join an outstanding research team dedicated to designing and executing studies using a new generation of RNA medicines. This individual will enjoy working in a pioneering, fast-paced,...

  • Scientist - Stem Cell Biology

    3 weeks ago

    Cambridge, United States GC Therapeutics Full time

    Company Overview GC Therapeutics is the first genome-wide cell landscape exploration company using an integrated synthetic biology and AI-driven platform for cell programming. Its patent-pending and proprietary pluripotent stem cell differentiation technology platform TFome™ was developed in Professor George Church’s lab, a pioneer in synthetic biology,...

  • Senior Associate Scientist

    4 days ago

    Cambridge, United States Simcere Full time

    Open Associate Scientists positions in Autoimmunity and Oncology (Preclinical)Simcere Pharmaceutical Group is building up its presence in North America with a newly formed drug discovery team in Cambridge, Massachusetts. We are seeking creative, energetic, and self-motivated associate scientists to join our preclinical team. This is an exciting opportunity...