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Research Associate – In Vivo Technician

4 months ago

Waltham, United States Affinia Therapeutics Full time

Affinia Therapeutics is an innovative gene therapy company with a vision to create a paradigm shift by broadening the reach of gene therapy to prevalent diseases. Our proprietary Affinia Rationally-designed Therapies (ART) platform was created to address key efficacy, safety, and cost of goods limitations of conventional gene therapies. We are backed by a strong syndicate of life science investors. Our purpose is to have a dramatic impact on the lives of patients around the world.


You will play a key role in shaping our culture and embodying our values of integrity, passion, and teamwork. You will be working alongside the management team who has a track record of success in the industry. The pace of work is dynamic, fast, and fun.


We offer a competitive salary and benefits with the ability to make a difference.


Position Summary


Affinia Therapeutics is seeking an In Vivo Research Associate to join our Preclinical Research team. You will be part of a team focused on performing preclinical-stage studies that are essential in supporting our next-generation gene therapy research.Reporting to the Director of In Vivo Studies, you will play a critical role in supporting multiple basic and complex in-life experiments. Working both independently and collaboratively across teams to execute the studies will be an important aspect of the position.


This position is located at our state-of-the-art facility, in Waltham, MA


Primary Responsibilities


  • Assist with in-vivo procedure setup and documentation preparation
  • Collect biological samples (blood, tissue) and perform gross assessments at necropsy
  • Administer test articles via multiple routes of administration (IV, RO, IP, SC) and monitor their effects
  • Provide pre and post-operative care in rodents to ensure proper analgesia and pain management
  • Working alongside contract technicians, ensure flawless animal care and welfare is conducted throughout the research studies
  • Maintain detailed records of experimental procedures and results
  • Generate and report data obtained from all in-vivo procedures
  • Review and adhere to all company standards, IACUC-approved SOPs and required safety procedures
  • May be required to perform other related duties as required and/or assigned


Minimum Qualifications


  • Must be able to work in a laboratory setting with direct exposure to/handling of laboratory animals
  • A minimum of 2 years of experience in animal research and husbandry, specifically working with mouse models
  • Proficient in multiple routes of administrations (IV-tail vein, SC, IP, RO)
  • Highly detailed and excellent record keeping, adhering to GLP-like standards
  • Ability to work independently on repetitive tasks quickly and efficiently
  • Excellent written and oral communications skills
  • Must be flexible and comfortable working in a fast-paced environment


Preferred Qualifications


  • Bachelor's degree (B.S./B.Sc.) in animal or life sciences related scientific area
  • AALAS Certification
  • Experience with cloud-based Benchling platform and Excel for maintaining records and data analysis
  • Previous experience working with multiple disease models and understanding of animal model characterization



EEO Statement: Affinia Therapeutics is proud to be an equal opportunity workplace. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.