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Senior Associate Scientist, Molecular Discovery

3 months ago


La Jolla, California, United States Pfizer Full time
Why Patients Need You

Everything we do, every day, is in line with an unwavering commitment to the quality and the delivery of safe and effective products to patients. Our science and risk-based compliant quality culture is flexible, innovative, and customer oriented. Whether you are involved in development, maintenance, compliance or analysis through research programs, your contribution will directly impact patients.

What You Will Achieve

Pfizer BioMedicine Design group at San Diego, CA is seeking a highly motivated Senior Associate Scientist with basic knowledge and hands-on experience in molecular biology and protein production to join a dynamic team in antibody discovery, optimization, and production.

How You Will Achieve

Work within a team on various antibody identification, optimization, and/or production projects in parallel
Implement molecular biology methods such as reformatting scFv to IgG and other modalities
Purify and deliver transfection-grade plasmids at various scales
Clone mRNA constructs and perform in vitro transcription (IVT)
Comfortable working with automation methods using liquid handling equipment
Design experiments, analyze data, and troubleshoot when issues arise, under supervision of senior colleague(s)
Present experimental design and results at internal meetings

Qualifications

Must-Have
B.S in Biological Science (Molecular Biology, Structural Biology, Biochemistry, Cell Biology) or a related field (Chemistry, Chemical Engineering, Biomedical Engineering and Biological Engineering) with 3+ years or M.S with 1-2 years of relevant experience in either an academic or industrial setting
Understand principles and have experience with some modern molecular biology techniques (primer design, vector design, PCR, gel extraction, restriction cloning, Gibson Assembly, In-Fusion, plasmid prep, sequencing verification), preferred in antibody engineering field.
Understand the underlying principles of the performed experiments and document timely.
Detail-oriented, outstanding proactive attitude, collaborative, self-aware, and strong interpersonal skills
Ability and desire to work in a fast-paced interdisciplinary scientific team and the desire to learn new techniques.
Strong time management skills and ability to manage multiple projects at the same time.

Nice-to-Have
Previous experience with protein and/or antibody engineering
Previous experience with Geneious or other sequence data analysis software
Tissue-culture sterile techniques, transient expression, basic antibody purification

PHYSICAL/MENTAL REQUIREMENTS
Lifting, sitting, standing, walking, bending, ability to perform mathematical calculations and ability to perform data analysis.

Other Job Details:
Last Date to Apply for Job: July 19th, 2024.
Work Location Assignment: On Premise
On Premise colleagues work in a Pfizer site because it's needed to get their job done. They may have flexibility to work remotely from time to time, but they are primarily on-site.

The annual base salary for this position ranges from $64,600.00 to $107, In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | ). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Research and Development