Flow Cytometry, Clinical Assay Development- Senior Scientist
4 weeks ago
HOW MIGHT YOU DEFY IMAGINATION?
Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.
Flow Cytometry, Clinical Assay Development- Senior Scientist
Live
What you will do
Lets do this. Lets change the world. In this vital role you will perform clinical biomarker assays employing a variety of platforms to support our drug development efforts.
This person will be an integral member of a dynamic group of scientists and platform experts Collaborate with scientists representing multiple therapeutic areas and work closely with groups in other functional areas. Employ multiparametric flow cytometry in our biomarker laboratory to develop and qualify biomarker assays to support various clinical programs Other responsibilities include independent thinking, choosing the appropriate platform, planning and performing laboratory experiments, documenting experimental protocols and results, analyzing and interpreting data, presenting results to the stakeholders and working with internal and external partners. WinWhat we expect of you We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a laboratory based scientist with these qualifications. Basic Qualifications: Doctorate degree PhD OR PharmD OR MD and relevant post-doc where applicable OR Masters degree and 3 years of scientific/technical experience OR Bachelors degree and 5 years of scientific/technical experience Preferred Qualifications: A strong background and experience in multiparametric flow cytometry assays including immunophenotyping, receptor occupancy and immune based functional assays is required for this position Using flow cytometry techniques to generate orthogonal data and controls for other areas of interrogation Ability to multi-task and manage multiple projects, strong verbal and written communication skills with a high degree of motivation, creativity and collaborative qualities Previous experience working in a matrixed environment to implement cell-based biomarker assay development and validation employing innovative approaches to support clinical trials Project management skills to meet critical timelines associated with various activities necessary to support biomarker assessment of clinical samples Demonstrated track record of critical independent thinking and troubleshooting ability and innovative approaches to solve complex questions is highly desirable Understanding of disease biology and biomarker approaches in multiple therapeutic area Work and coordinate with internal stakeholders as well as external partners such as CROs and vendors to support outsourced activities Familiarity with processes and factors needed to evaluate and qualify CROs Experience collaborating with CROs to coordinate data and assay transfers, and real time monitoring of assay performance Familiarity with data qc processes Experience with complex data analysis software for flow cytometry such as FlowJo, FCS Express, OMIQ.AI, SPADE, viSNE and CITRUS Experience in cell culture and cell isolation techniques Experience with other biomarker assay platforms such as immunoassays (ELISA, Luminex, MSD, etc), immunohistochemistry, western blotting and genomics is a plus ThriveWhat you can expect of us As we work to develop treatments that take care of others, we also work to care for our teammates professional and personal growth and well-being. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including: Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans and bi-annual company-wide shutdowns Flexible work models, including remote work arrangements, where possible Apply nowfor a career that defies imagination Objects in your future are closer than they appear. Join us. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.-
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