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Precision Medicine Therapeutic Area

3 months ago

Washington, Washington, D.C., United States Amgen Full time

HOW MIGHT YOU DEFY IMAGINATION?

If you feel like youre part of something bigger, its because you are. At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies. We are global collaborators who achieve togetherresearching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. Its time for a career you can be proud of.

Precision Medicine Therapeutic Area Lead, InflammationLive

What you will do

Lets do this. Lets change the world. In this vital role you will act in conjunction with the Inflammation Therapeutic Area head to advance the development and execution of Precision Medicine objectives. Lead a cross-functional team to develop and execute translational and precision medicine strategies to support asset (and above-asset, as needed) development across the product lifecycle. Additionally, partner with cross functional Therapeutic Area leads across Research & Development to guide the development of translational, reverse translational, and precision medicine strategies.

Serve as the strategic integrator of various stakeholder inputs and multiple lines of evidence for the development of translational medicine and precision medicine strategies at asset and/or indication level.Set strategic vision to enhance the value of the asset across the product lifecycle through clinical biomarker target identification, indication selection, early indication of biological activity and patient stratification/selection including reverse translation strategies.Course correct as needed by incorporating deep mechanistic insights and omics signatures into actionable precision medicine strategies.Lead cross-functional teams in the development and execution of phase appropriate, integrated, biomarker and human data plans, to support translational pharmacology and inform patient selection strategies.Serve as the key liaison between research and development by providing clinical translational considerations (proof of target engagement, dose selection, patient selection) to inform discovery asset development as well as enabling reverse translational strategies (to gain mechanistic insights related to patient stratification, response/resistance) for assets in clinical phase.Provide precision medicine considerations to shape disease area strategies (disease endotypes, indications, and combinatorial approaches). Provide subject matter expertise to inform registrational and access and use evidence generation plans.Work cross-functionally to evaluate appropriate data sources and strategies for translational/precision medicine execution and propose funding/collaboration needs to appropriate Commercialization Governance Forums.WinWhat we expect of you We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications. Basic Qualifications: Doctorate degree and 4 years of relevant experience OR Masters degree and 7 years of relevant experience OR Bachelors degree and 9 years of relevant experience Preferred Qualifications:MD & PhD with 6+ years industry & academic experienceDeep scientific and analytical expertise in integrating multiple data sources e.g. omic, clinical, Real world evidence (RWE) to inform precision medicine approachesStrong professional network with external Key Opinion Leaders, academic institutions, and industry partnersExperience in translational research and/or advancing clinical candidatesKnowledge of Good Clinical Practices (GCP) and applicable regulatory requirements for biomarker and diagnostic developmentProven ability to lead, manage, and motivate others in a complex, multi-functional matrix environmentExceptional leadership and team management skillsThriveWhat you can expect of us As we work to develop treatments that take care of others, we also work to care for our teammates professional and personal growth and well-being. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including: Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.A discretionary annual bonus program, or for field sales representatives, a sales-based incentive planStock-based long-term incentivesAward-winning time-off plans and bi-annual company-wide shutdownsFlexible work models, including remote work arrangements, where possibleApply nowfor a career that defies imagination Objects in your future are closer than they appear. Join us. Application deadlineAmgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.