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Scientist, Genome Engineering

4 months ago


Dallas, Texas, United States Colossal Biosciences Full time

The Scientist provides their talent, knowledge, and passion for ambitious synthetic biology projects involving non-model organisms. The role requires working on a diverse set of workflows that involve precise genome manipulation. The candidate will work with a talented group of engineers and biologists committed to optimizing and developing novel technologies for large-scale editing of genomes.

**This position may be based out of Dallas, TX or Boston, MA. Relocation assistance is available**

Duties and Responsibilities:

  • Build and collaborate on multiplex genome-editing workflows
  • Design, innovate and iterate DNA assembly, integration, screening and functional assays
  • Work on project milestones
  • Attend lab meetings, prepare reports and presentations on the progress of projects
  • Great organizational skills and excellent laboratory record maintenance

Required Skills and Abilities:

  • Expertise with a variety of genome editing tools (CRISPR and more)
  • Strong experience with mammalian cell culture systems
  • Experience in molecular biology (PCR, nucleic and protein extraction, gel electrophoresis) and cloning techniques (restriction enzyme-based cloning, Gibson and Golden Gate assembly, yeast assembly)
  • Strong written and oral communication skills, as well as creative problem-solving skills
  • Enjoys the fast-paced startup environment and teamwork
  • Ability to function well in a growth-oriented, nimble environment.

Preferred Experience:

  • Postdoctoral/industry work in gene editing, cell selection and cell screening
  • Experience with large scale DNA assemblies
  • Experience with NGS analysis workflows
  • Peer-reviewed work on genome engineering in mammalian cell systems

Education and Experience:

  • PhD in synthetic biology, biological sciences, bioengineering, molecular biology, genetics or related field.
  • 3+ years hands-on expertise designing and cloning DNA constructs

What Colossal Offers You:

  • Medical, dental, and vision coverage
  • Unlimited PTO and company holidays so you can rest and recharge
  • Flexible spending accounts (FSA)
  • Company matched 401k retirement plan
  • Paid parental leave up to 12 weeks
  • Education reimbursement
  • An opportunity to help us return the Earth to a healthier state

The team at Colossal is committed, colorful, passionate, intelligent, collaborative, creative, experienced, scientific and world-class. That sounds like a lot to fit into one building. That's why we are spread out in three locations that include laboratories, test facilities, academic institutions, libraries and offices. Dallas. Austin. Boston.

Through it all, however, we maintain a culture of positivity, hope, happiness and belief that we're doing something big. Something Colossal.

Colossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive.

EEO is the Law

Search Firm Representatives: Colossal does not accept unsolicited assistance from search firms. No fees will be paid for a hired candidate where no pre-existing agreement is in place. We handle recruitment in-house.

Colossal is proud to be named a Best Place to Work by Built In across 4 categories in 2023 & 2024:

  • #1 on the 50 Best Startups to Work For in Dallas in 2023
  • 100 Best Midsize Places to Work in Dallas in 2024
  • 100 Best Places to Work in Dallas, TX (All Size Employers) in 2024
  • 100 Best Midsize Places to Work in Boston in 2024

Built In 2024 Award Lists

Great Place to Work Certification Page

Most Loved Workplace Certification Page - Proud to be certified as a most loved workplace including: most loved CEO, most loved workplaces for LGBTQ+, most loved workplaces for women, and most loved workplaces for young professionals.