Post-doctoral position in brain activity development

2 weeks ago

Washington, Washington, D.C., United States The George Washington University School of Medicine Full time
The Laboratory of Systems Neural Development (PI Matthew Colonnese. ) at The George Washington University in Washington DC is recruiting post-doctoral scientists for two newly funded projects to investigate the functional development of thalamocortical circuits in vivo.

The lab uses multi-electrode arrays (Neuropixels, Neuronexus), patch clamp, and calcium imaging combined with viral-driven expression of DREADDs and opsins during the first post-natal week to determine the circuit basis of activity in the developing visual system.

Our current work focuses on the role of the thalamus in the generation of network oscillations during circuit formation, and the specific roles of thalamic and cortical cell types in the evolution of the EEG.

One of the major goals of the lab is to create an atlas linking underlying circuit dysfunction to changes in the EEG of preterm and perinatal infants.

The other is to understand the role of activity in the formation of thalamocortical circuits.

The ideal candidate is a recent graduate with experience with electrophysiology or optical imaging interested in working in vivo in neonatal rodents, or a developmental neuroscientist interested to learn modern techniques for in vivo recording.

Experience with programming, signal processing, viral expression, fiber photometry, slice recording and/or computational modeling of circuits are all pluses. Candidates that increase the diversity of the lab are particularly encouraged to apply. Please send a CV and description of interest to Matt Colonnese, for more information and to apply.

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