Scientist I, Early Preclinical Development

4 weeks ago

Boston, Massachusetts, United States Eli Lilly and Company Full time

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

The Early Preclinical Development (EPD) team is seeking a Scientist, preferably with in-depth knowledge of inner ear histology, to support the development of product candidates from early discovery through IND-enabling stages. The ideal candidate will report to the Director of Early Preclinical Development, Histology and will work closely with a team of scientists aiming to develop therapies that have the potential to restore and preserve hearing. The scope of work includes the execution of in vivo and ex vivo experiments in mice and non-human primates (NHPs). The successful candidate will be self-motivated and creative, with a desire to succeed at the highest level in a highly collaborative and fast-paced environment.

Duties and Responsibilities:

Execute in vivo and/or ex vivo nonclinical experiments for the development of gene therapies for the inner ear:Perform histologic preparations of mouse and NHP inner ear tissue, including whole-mount dissections and/or cryosections and immunohistochemistryPerform epifluorescent and confocal microscopyPerform necropsies and/or tissue harvest from mice and inner ear tissue harvest from NHPsMaintain accurate and timely documentation of activities through meticulous lab notebook practices and contributions to reportsPerform and develop analyses of histologic data and find efficiencies for histologic processesParticipate in weekly scientific and cross-functional meetings to communicate procedures, results, and data interpretation; summarize integrated datasets from different functional teams in EPDCollaborate closely with cross-functional teams and external groups to coordinate and drive complex studiesBasic Qualifications:PhD in neuroscience, molecular, cellular biology, or similar field.Additional Skills/Preferences:3 years of hands-on experience working in a laboratory environment; biotech, or biopharma industry preferredProven ability to work as a member of an interdisciplinary team and contribute to a highly collaborative environmentHighly creative, organized, and detail-orientedExcellent analytical and problem-solving skillsExcellent communication skills, with the ability to thoroughly document, interpret, and effectively present scientific data to other scientistsExcellent computer skills and Microsoft Products proficiency (Outlook, Excel, Word, PowerPoint, etc.) Proficient in epifluorescent and confocal microscopyKnowledge of cochlear anatomy, cochlear microdissection (whole-mount or sections), and methods for histological preparation of inner ear tissues preferredExperience in data analysis using image analysis software, such as ImageJ, Amira, or ImarisExperience in solving scientific problems and/or image analysis using programming languages in at least one language such as Python or MATLAB Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively "Lilly") are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women's Network, Working and Living with Disabilities. Learn more about all of our groups. #WeAreLilly

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