Associate Scientist, Early Preclinical Development

Found in: beBee jobs US - 2 weeks ago


Boston, Massachusetts, United States Eli Lilly and Company Full time

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

Akouos, a wholly owned subsidiary of Eli Lilly and Company, is building a leading gene therapy company focused on hearing disorders. We are a precision genetic medicine company focused on developing gene therapies with the potential to restore, improve, and preserve high-acuity physiologic hearing for individuals who live with disabling hearing loss worldwide.

Restoring, improving, and preserving high-acuity hearing is an area of high unmet need in medicine: 466 million people worldwide have disabling hearing loss, and there are no FDA-approved pharmacologic therapies to address its underlying causes.

Akouos was founded in 2016 by leaders in the fields of neurotology, genetics, inner ear drug delivery, and AAV gene therapy. Listening is in our DNA. We believe the only way to achieve our ambitious goals is to engage as one team, listen to each other, and trust in ourselves and our science.

The Early Preclinical Development (EPD) Team is seeking an Associate Scientist with experience in inner ear histology to support discovery and IND-enabling animal studies. The ideal candidate will have experience in histologic techniques specific to the inner ear, such as microdissection of the mouse and non-human primate (NHP) inner ear tissues into discrete anatomical regions, and further processing of these tissues using various histologic techniques, in addition to imaging, analysis, and preparation of data for presentation. Cross-functional work may be required to advance Company goals. The successful candidate will be self-motivated and creative, with a desire to succeed at the highest level in a highly collaborative and fast-paced environment.

Job Responsibilities:

Perform mouse and NHP inner ear microdissectionsPerform NHP temporal bone extraction and processingPrepare inner ear tissues for embedding and preparation for frozen sectionsPreparation of inner ear tissues for molecular analysesPerform immunohistochemistryPerform epifluorescent imaging, cochlear frequency mapping, and confocal microscopyProduce graphs and charts from histologic dataPreparation of histologic images for presentationDevelopment and/or review of immunohistochemistry protocolsInventory ordering and database managementCollaborate closely with cross-functional teams and external groups to coordinate and drive complex studiesWeekend work may be required at timesBasic Qualifications:Bachelor's Degree with 0+ years of experience, or high school diploma and 2+ years of hands-on experience with inner ear biology.Additional Skills and Preferences:Experience in solving scientific problems and/or image analysis using programming languagesExperience and programming skills in at least one language such as Python or MATLABKnowledge of cochlear anatomy, cochlear microdissection (whole-mount and sections), and methods for histological preparation of inner ear tissues requiredExperience with modern imaging techniques; epifluorescent and confocal microscopy requiredExcellent computer skills; proficiency in Microsoft Office (Word, Excel, Teams, PowerPoint, Outlook, Adobe Suite)Experience with image analysis software (ImageJ, Amira, LasX, Imaris); may include codingExcellent laboratory technical lab skills (pipetting, reagent preparation, liquid handling) Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively "Lilly") are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women's Network, Working and Living with Disabilities. Learn more about all of our groups. #WeAreLilly

  • Associate Scientist

    Found in: beBee jobs US - 2 weeks ago


    Boston, Massachusetts, United States Eli Lilly and Company Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...

  • Associate Development Scientist II

    Found in: beBee jobs US - 3 days ago


    Boston, Massachusetts, United States Eli Lilly and Company Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...

  • Senior Associate Scientist, DMPK

    Found in: beBee jobs US - 2 weeks ago


    Boston, Massachusetts, United States Cerevel Therapeutics Full time

    Our portfolio of pre-commercial neuroscience assets targets a broad range of central nervous system (CNS) disorders, including schizophrenia, epilepsy, Parkinson's disease and substance use disorder.This is an exciting role for a Senior Associate lab scientist to be part of the growing DMPK (Bioanalytical) group here at Cerevel.The ideal candidate will be...

  • Associate Scientist, Protein Engineering

    Found in: beBee jobs US - 2 weeks ago


    Boston, Massachusetts, United States Proclinical Staffing Full time

    Senior Associate Scientist, Protein Engineering & Bioconjugation - Permanent - OnsiteProclinical is seeking a Senior Associate Scientist, Protein Engineering & Bioconjugation to join a stealth biotech company.The Senior Associate Scientist will be a motivated and curious researcher, with willingness to learn about numerous areas of bioconjugation, chemistry...

  • Bioinformatics Scientist

    Found in: beBee jobs US - 2 weeks ago


    Boston, Massachusetts, United States Eli Lilly and Company Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...

  • Scientist (Biologics Cell Line Development)

    Found in: beBee jobs US - 2 weeks ago


    Boston, Massachusetts, United States Asimov Full time

    Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform––from cells to software––to enable the design and manufacture of next-generation therapeutics.Asimov, Inc. seeks a full time Scientist at our offices...

  • data scientist

    Found in: beBee jobs US - 3 weeks ago


    Boston, Massachusetts, United States Tangle Systems LLC Full time

    Tangle System has an immediate requirement for Data Scientist in Boston MAThe AIML (Artificial Intelligence and Machine Learning) team contributes to the vitality and growth of the organization through researching and building complex cutting edge and scalable AI algorithms models platforms and technologies to significantly improve customer experience and...

  • Scientist

    Found in: beBee jobs US - 3 weeks ago


    Boston, Massachusetts, United States Asimov Full time

    Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform––from cells to software––to enable the design and manufacture of next-generation therapeutics. Asimov, Inc. seeks a full time Scientist at our offices...

  • Sr. Scientist, Analytical Development

    Found in: beBee jobs US - 3 weeks ago


    Boston, Massachusetts, United States Scorpion Therapeutics Full time

    Scorpion is a pioneering clinical-stage oncology company redefining the frontier of precision medicine to deliver optimized and transformational therapies for larger populations of patients with cancer. Scorpion has built a proprietary and fully integrated platform of the most advanced technologies across cancer biology, medicinal chemistry, and data...

  • Industrial Sales Account Manager

    Found in: beBee jobs US - 2 weeks ago


    Boston, Massachusetts, United States ABclonal Full time

    Based in Massachusetts, ABclonal is a dynamic and growing provider of biology research reagents and services.With scientists from world-class universities, we thrive to improve the quality of life science research by providing high-quality antibodies, proteins, ELISA kits, NGS Prep Kits and molecular enzymes.Our advanced technology allows the development of...

  • Early Childhood Lead Coach

    Found in: beBee jobs US - 3 weeks ago


    Boston, Massachusetts, United States University of Massachusetts Boston Full time

    Job no: 522722Position Type: Staff Full TimeCampus: UMass BostonDepartment: Institute for Early EducationPay Grade: 33 Date opened: 26 Mar 2024 Eastern Daylight TimeApplications close: 26 Apr 2024 Eastern Daylight TimeGeneral Summary: The Early Childhood Lead Coach will be responsible for the delivery of coaching services as part of the leadership coaching...

  • Associate Director, Clinical Pharmacology

    Found in: beBee jobs US - 2 weeks ago


    Boston, Massachusetts, United States Fusion Pharmaceuticals Full time

    Fusion is looking for an Associate Director, Clinical Pharmacology/ DMPK to join non-clinical development group.The incumbent will be responsible to lead and execute clinical pharmacology/ DMPK strategies and studies for early through late-stage clinical development programs.The successful candidate must have experience and foundational knowledge and...

  • Associate Director, Clinical Pharmacology

    Found in: beBee jobs US - 2 weeks ago


    Boston, Massachusetts, United States Fusionpharma Full time

    Associate Director, Clinical Pharmacology/DMPK Management Boston, MA, USFusion is looking for an Associate Director, Clinical Pharmacology/ DMPK to join non-clinical development group.The successful candidate must have experience and foundational knowledge and experience in clinical pharmacology, drug metabolism, pharmacokinetics, bioanalytical and PK/PD...

  • Applied Scientist III, Alexa

    Found in: beBee jobs US - 2 weeks ago


    Boston, Massachusetts, United States Amazon Full time

    The Devices and Services Security team is looking for a passionate, talented, and inventive Senior Applied Scientist with a strong deep learning background, to secure the development of industry-leading Generative AI systems.As a Senior Applied Scientist with the Devices & Services Security team, you will lead the development of novel algorithms and modeling...

  • Data Scientist I

    Found in: beBee jobs US - 2 weeks ago


    Boston, Massachusetts, United States Putnam Associates LLC Full time

    Position SummaryAs a Data Scientist I at Putnam, you will help lead and manage Data Analysts alongside case team leaders to solve interesting analytical problems for the clients. You will be instrumental in developing the core deliverables of analytics engagements by applying coding and modelling skills. In this role you will work with the project case team...

  • Senior Data Scientist

    Found in: beBee jobs US - 6 days ago


    Boston, Massachusetts, United States Pison Full time

    Pison is developing breakthrough consumer and healthcare products that are harnessing the power of the mind. We've pioneered the science of electroneurography (ENG) to non-invasively sense, analyze, and apply electrical signals coming from the brain. Our neural biosensor and artificial intelligence software are opening a new window to thousands of new,...

  • Senior Data Scientist

    Found in: beBee jobs US - 3 weeks ago


    Boston, Massachusetts, United States Infinite Analytics Full time

    *Company Overview:*Infinite Analytics' AI platform, Sherlock, is transforming the way businesses gain consumer insights through its powerful knowledge graph. By leveraging the latest advancements in AI and machine learning, our no-code SaaS platform empowers enterprises to analyze consumer behavior in both the physical and digital worlds. With a knowledge...

  • Director of DMPK

    Found in: beBee jobs US - 2 weeks ago


    Boston, Massachusetts, United States RBW Consulting Full time

    RBW are currently working in close partnership with a global biopharmaceutical company that are looking for a new Director of ADME/DMPK to join their team. You will be responsible for developing the DMPK strategy across all metabolism related aspects such as in vitro ADME, bioanalysis, biotransformation and transporters. This opportunity will also involve...

  • Research Scientist, Molecular And Cell Biology

    Found in: beBee jobs US - 3 weeks ago


    Boston, Massachusetts, United States QLD Biotherapeutics Inc Full time

    We are seeking a highly motivated molecular biologist to join the AAV therapeutics team, focusing on early drug discovery and technology development.This position provides an excellent learning and growth opportunity, to work closely with an experienced drug discovery and development team and contribute to early stages of research and development activities...

  • Research Scientist

    Found in: beBee jobs US - 2 weeks ago


    Boston, Massachusetts, United States isee ai Full time

    ISEE is seeking a full-time Senior Research Scientist - Prediction to join our team. The ideal candidate has 5+ years of relevant experience in behavior or trajectory prediction, computer vision, motion planning, machine learning, or related areas.Role responsibilities include:Architect and build pipelines for training and evaluating models on real driving...