Postdoctoral Fellow
1 month ago
HOW MIGHT YOU DEFY IMAGINATION?
Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.
Postdoctoral Fellow - Pivotal Biologics Drug Substance
Live
What you will do
Lets do this Lets change the world
Amgen is seeking a Postdoctoral Fellow to support late stage process development work to advance the Amgen pipeline as part of Pivotal Drug Substance Process Development organization. The Pivotal Drug Substance Process Development organization at Amgen develops, characterizes, and supports the commercialization of the drug substance manufacturing processes for all late-stage programs across the Amgen portfolio. This role is integrated cross-functionally with Pre-Pivotal Attribute Sciences and Drug Substance Technologies Synthetics.
We are looking for a highly motivated and skilled post-doctoral researcher to join our cross-functional team and work on a project aiming to characterize the relationship between cell culture conditions and product quality attributes The selected candidate will develop scale-down cell culture models and use purification & analytical methods including an automated liquid handling system to purify proteins and execution of peptide mapping workflows. The successful candidate will have a strong background in cell culture and experience in analytical chemistry techniques such as LC-MS or other relevant techniques. Design, perform, and analyze experiments using scale-down cell culture models to determine impact of cell culture parameters on key product quality attributes. Develop and optimize protocols and methods for cell culture characterization and LC-MS analysis. Collaborate with other researchers in the department and external partners to inform experimental plans and hypotheses and integrate data and findings from different sources and disciplines. Prepare and present research results in scientific meetings and publications. WinWhat we expect of you We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is an individual with these qualifications. Basic Qualifications: PhD at time of appointment Preferred Qualifications: PhD in Chemical Engineering, Biomedical Engineering, Bioengineering, Chemical Biology, Biochemistry, Analytical Chemistry or a related field Consistent track record of problem solving and troubleshooting protein drug substance processes including cell culture process development, cell line development, and/ or high throughput screening technologies Demonstrated expertise in mammalian cell culture including aseptic technique Hands-on experience in analytical methodology, such as LC-MS, HPLC, or other relevant techniques. Understanding of protein characteristics, protein chemistry, posttranslational modification and critical attributes to direct cell culture process development and control strategies Familiarity with laboratory automation, data analysis and visualization techniques and tools Highly motivated individual, who takes initiative and has strong interpersonal, presentation, written and verbal skills Works effectively in a diverse and multi-disciplinary team including cell culture scientists, analytical scientists, engineers, and chemists Critical thinking, problem solving and independent research skills. Good organizational skills with strong attention to detail Strong ability to operate well in a fast-paced, matrixed environment and collaborate successfully cross-functionally The position is for two years and will start on or after 9/30/2024. ThriveWhat you can expect of us As we work to develop treatments that take care of others, we also work to care for our teammates professional and personal growth and well-being. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including: Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans and bi-annual company-wide shutdowns Flexible work models, including remote work arrangements, where possible Apply nowfor a career that defies imagination Objects in your future are closer than they appear. Join us. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.-
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