Senior Scientist, Cell Therapy Analytical Development
3 weeks ago
We are seeking a highly effective, self-motivated Senior Scientist to join our Analytical Development team at Turnstone Biologics. In this role, you will contribute to the advancement of our cell therapy programs, particularly in developing next-generation T-cell therapies for solid tumors. The ideal candidate will be responsible for innovating, designing, developing, troubleshooting, and implementing analytical methods. Key responsibilities include independently designing and conducting experiments, analyzing, and interpreting results, and effectively communicating findings in team meetings. Additionally, the role requires collaboration with internal and external partners, including CDMO and CRO. This position is suited for someone who is passionate about cell therapy and thrives in a fast-paced, collaborative environment. The successful candidate will also perform qualification/validation and tech transfer of assays, routine testing of drug product (DP) and in-process samples. The position is an onsite, lab-based role in La Jolla, CA, with responsibilities as an individual contributor, reporting to the Director of Analytical Development.
KEY RESPONSIBILITIES
- Independently design, develop, optimize, troubleshoot, and qualify analytical methods to support drug product (DP) release and characterization ensuring technical excellence.
- Evaluate new and innovative technologies for determining drug product potency and product/process impurities.
- Plan and execute routine DP testing activities, including in-process and stability samples, using flow cytometry and ELISA/Ella to support regulatory submissions.
- Lead assay transfer to external partners and training analysts.
- Author, review and own test methods/SOPs, qualification protocols, and technical reports in accordance with regulatory guidelines.
- Document laboratory procedures and experiments with great attention to detail, including Electronic Lab Notebook (ELN) record keeping.
- Analyze data, prepare reports and data packages for communicating with key stakeholders, senior management, and external partners.
- Coordinate tasks across functions, demonstrating prioritization and planning skills.
- Present work to key stakeholders and leadership.
- Provide assistance and mentorship to junior team members.
- Willingness to travel to external partner locations for method‑related support, when necessary.
- Additional duties as assigned.
PROFESSIONAL EXPERIENCE/QUALIFICATIONS
- Ph.D. in Biology with at least 4+ years of relevant industry experience.
- Strong preference for candidates with experience in immuno-oncology with a focus on engineered T cells and/or other immune cell types.
- Proficiency in a wide range of analytical techniques, including but not limited to multi-parametric flow cytometry, ELISA/MSD, and qPCR/ddPCR.
- Experience in multi-color flow cytometry analyses, including panel design and data analysis is essential.
- Experience in developing cell-based potency assay will be a plus.
- Ability to work in a highly adaptive environment and learn new skills for changing priorities.
- Knowledge of cGMP and regulatory guidelines (e.g., FDA, EMA) and a track record of ensuring compliance in analytical operations.
- Good understanding of ICH guidelines for assay qualification/validation.
- Basic understanding of method lifecycle management from development to validation and beyond.
- Ability to analyze and interpret data and contextualize with the program goals and requirements in a phase-appropriate manner.
- Demonstrated resilience, influence, relationship-building, and problem-solving skills in a variety of situations.
- Experience managing, mentoring, and engaging direct reports is a plus.
- Self-motivated, detail-oriented, and willing to accept temporary responsibilities outside of initial job description.
- Demonstrated ability to manage multiple tasks/projects with demanding timelines.
- Strong interpersonal, teamwork, and organizational skills; effective oral and written communication skills.
- Occasional travel to support cross-functional workshops or strategy/planning activities.
COMPENSATION/BENEFITS
At Turnstone, we prioritize the well-being and success of our team. Join us and enjoy a competitive compensation package, including a base salary and performance-based bonuses. Our comprehensive benefits include:
Healthcare Coverage: Medical, dental, and vision insurance for you and your dependents.
Retirement Planning: 401(k) plan with employer contributions.
Time Off: Generous paid time off, including vacation, sick leave, and holidays.
Workplace Flexibility: Flexible schedules and remote work options.
-
Scientist, Cell Therapy Analytical Development
3 weeks ago
San Diego, United States Turnstone Biologics Full timeWe are seeking a highly effective, self-motivated Scientist to join our Analytical Development team at Turnstone Biologics. In this role, you will contribute to the advancement of our cell therapy programs, particularly in developing next-generation T-cell therapies for solid tumors. The ideal candidate will be responsible for developing, qualifying, and...
-
Scientist, Cell Therapy Analytical Development
3 weeks ago
San Diego, United States Turnstone Biologics Full timeWe are seeking a highly effective, self-motivated Scientist to join our Analytical Development team at Turnstone Biologics. In this role, you will contribute to the advancement of our cell therapy programs, particularly in developing next-generation T-cell therapies for solid tumors. The ideal candidate will be responsible for developing, qualifying, and...
-
Senior Scientist, Cell
4 weeks ago
San Diego, California, United States Pharmaron Full timeThe Senior Scientist will play a pivotal role by supporting in vivo studies to test cell and gene therapy treatments.The Senior Scientist serves as Study Director and is responsible for the oversight and conduct of in-vivo studies involving the testing of pharmaceutical compounds and cell and gene therapy.The Study Director functions as a key member of the...
-
Associate Scientist, Analytical Development
4 days ago
South San Francisco, CA, United States Cellares Full timeSouth San Francisco, CAProcess Sciences – Analytical Development /Full Time /On-sitePosition SummaryWe are seeking an innovative and highly motivated Associate Scientist in Analytical Development who will contribute to the development of our advanced cell therapy manufacturing platform. The primary focus of this position is development, optimization,...
-
San Diego, United States Akkodis Full timePosition SummaryWe are looking for a talented and experienced individual to join our growing team as our Analytical Senior Scientist or Scientist. This scientist will be responsible for designing, running, and reporting experiments related to the small molecule chemistry, degradation pathways, characterization, and stabilization techniques. The selected...
-
San Diego, United States Akkodis Full timePosition SummaryWe are looking for a talented and experienced individual to join our growing team as our Analytical Senior Scientist or Scientist. This scientist will be responsible for designing, running, and reporting experiments related to the small molecule chemistry, degradation pathways, characterization, and stabilization techniques. The selected...
-
Sr. Scientist
1 week ago
San Diego, United States Meet Full timeMeet's partnered with an exciting and growing biotech in San Diego for a Senior Scientist / Principal Scientist Analytical Development!You'll be responsible for designing, executing, and reporting on the analytical development of small molecule chemistry experiments, degradation pathways, characterization, and stabilization techniques for ophthalmic and...
-
Sr. Scientist
1 week ago
San Diego, United States Meet Full timeMeet's partnered with an exciting and growing biotech in San Diego for a Senior Scientist / Principal Scientist Analytical Development!You'll be responsible for designing, executing, and reporting on the analytical development of small molecule chemistry experiments, degradation pathways, characterization, and stabilization techniques for ophthalmic and...
-
San Diego, United States Meet Full timeMeet's partnered with an exciting and growing biotech in San Diego for a Senior Scientist / Principal Scientist Analytical Development!You'll be responsible for designing, executing, and reporting on the analytical development of small molecule chemistry experiments, degradation pathways, characterization, and stabilization techniques for ophthalmic and...
-
San Diego, United States Meet Full timeMeet's partnered with an exciting and growing biotech in San Diego for a Senior Scientist / Principal Scientist Analytical Development!You'll be responsible for designing, executing, and reporting on the analytical development of small molecule chemistry experiments, degradation pathways, characterization, and stabilization techniques for ophthalmic and...
-
Principal Scientist
4 weeks ago
South San Francisco, United States Life Science People Full timeJob Title: Senior Scientist/ Principal ScientistLocation: South San Francisco, CA Company Overview:Join a pioneering global biotech company at the forefront of cellular therapies, focusing on advanced dual-targeting CAR-T products. With a strong commitment to addressing unmet medical needs, backed by substantial financial support, my client is poised to...
-
Principal Scientist
4 days ago
South San Francisco, United States Life Science People Full timeJob Title: Senior Scientist/ Principal ScientistLocation: South San Francisco, CA Company Overview:Join a pioneering global biotech company at the forefront of cellular therapies, focusing on advanced dual-targeting CAR-T products. With a strong commitment to addressing unmet medical needs, backed by substantial financial support, my client is poised to...
-
Vice President, Regulatory Affairs
4 days ago
San Diego, United States Device Search Group Defunct Full timeWe are seeking an experienced Senior Director or Vice President of Regulatory Affairs (DOE). As the head of Regulatory Affairs you will be responsible for leading and managing all aspects of Clinical and CMC Regulatory Affairs. The ideal candidate will have a strong background in cell therapy with experience in early development regulatory affairs (pre-IND...
-
Vice President, Regulatory Affairs
6 days ago
San Diego, United States Device Search Group Full timeWe are seeking an experienced Senior Director or Vice President of Regulatory Affairs (DOE). As the head of Regulatory Affairs you will be responsible for leading and managing all aspects of Clinical and CMC Regulatory Affairs. The ideal candidate will have a strong background in cell therapy with experience in early development regulatory affairs (pre-IND...
-
Associate Scientist, Bioassays
6 days ago
San Diego, United States Arrowhead Pharmaceuticals Full timeArrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable...
-
Senior Scientist or Principal Scientist
4 weeks ago
South San Francisco, United States Trova Talent Full timeJob DescriptionJob DescriptionMy client is seeking a highly motivated, self-driven, collaborative and experienced individual with strong iPSC and cell engineering background. The successful candidate will be accountable for establishing control laboratory operation for iPSC seed stock production. This role requires dedication to drive science, ability to...
-
Sr. Scientist, Sequencing Assay Development
3 weeks ago
San Diego, United States BioPhase Solutions Full timeJob DescriptionJob DescriptionSummaryThis role will be responsible advancing company knowledge of cell and gene therapy sequencing assays through innovative experimental design and efficient execution. The ideal candidate will have a proven track record in successfully developing new sequencing methods, working closely with a multidisciplinary team of...
-
Senior Scientist, PET Biology
4 weeks ago
San Diego, California, United States AlzForum Foundation Inc Full timeIts work requires deep scientific expertise in many disciplines including chemistry, radiochemistry, cellular and molecular pharmacology, enzymology, and imaging technologies coupled with an ability to work collaboratively with internal and external partners.It is currently seeking an outstanding individual to join our team as senior scientist biology &...
-
Scientist, Mass Spectrometry
4 weeks ago
South San Francisco, United States Parvus Therapeutics Full timeJob DescriptionJob DescriptionParvus Therapeutics Inc. Parvus Therapeutics Inc. is a privately held biopharmaceutical company developing Navacims™, a platform technology based on foundational research published in 2016 (Nature 530:434), to treat autoimmune diseases. Parvus’ mission is to shift the treatment paradigm toward Navacim™-directed immune...
-
Senior Associate Scientist, In Vitro
2 weeks ago
South San Francisco, United States Allogene Therapeutics, Inc. Full timeAbout Allogene: Allogene Therapeutics, with headquarters in South San Francisco, is a clinical-stage biotechnology company pioneering the development of allogeneic chimeric antigen receptor T cell (AlloCAR T) products for cancer and autoimmune disease. Led by a management team with significant experience in cell therapy, Allogene is developing a pipeline of...