Oligonucleotide Chemist 1

3 weeks ago


San Diego, United States Manpower San Diego Full time

Job Summary

Responsible for the manufacture of GMP oligonucleotides; the continuous improvement of these existing oligo processes; and the development/transfer of new oligo processes. Provides oligo process support to Operations group through instrument/oligo process troubleshooting and completion of NCR investigations. Responsible for research, development and production manufacturing activities associated with oligos.


Essential Duties and Responsibilities

The incumbent may be asked to perform other function-related activities in addition to the below mentioned responsibilities as reasonably required by business needs.

  • produces notebook, dev, pilot and production materials per written directions
  • in-process and final oligos using state of the art analytical techniques
  • simple manufacturing process problems
  • process data
  • documents and assists with assembly of change control packages
  • labs under cGMP conditions
  • ERP and cycle count transactions
  • accurate records and documentation
  • and maintains lab supplies.


Qualifications

Education

Typically requires a Bachelor of Science degree or equivalent and a minimum of 0-2 years related experience.


Experience

Working knowledge of QSR/GMP

Proficiency with MS Word and Excel

Strong math skills

Basic EDMS change control skills and ERP knowledge

Working knowledge of oligo synthesis, purification, desalting and diafiltration processes

Working knowledge of analytical chemistry specific to oligos. (Maldi MS, HPLC, OD, etc.)


Skills

Analytical

Communication

Teamwork

Learning

Initiative

Problem Solving

Interpersonal skills



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