Scientist
3 weeks ago
1 Year Contract
Cambridge, MA
PR: $50 - $62/hour
Job Summary
Design and implement experiments to screen for drug candidates, and to address mechanisms-of-action of therapeutic molecules. Perform complex cell-based functional experiments independently. Act as a subject matter expert (SME) for drug discovery in the GI and inflammation therapeutic area.
Job Responsibilities
- Provide broad assay development support for early stage drug discovery projects in disease areas of the GI track and inflammation
- Design, execute and validate a variety of assays to understand mechanism of action and characterize different biologics
- Collaborate with automation engineers to identify suitable approaches to utilize laboratory automation for the execution of variable cell based assays
- Spend ~ 85% of time in laboratory to maintain and implement cell based assay platform and perform experiments
- Interface with project teams to meet timelines for project progression
- Present research findings clearly and effectively at internal and external meetings
- Troubleshoot complex problems in creative and effective ways
Education & Qualifications
- MS with 2+ years’ experience, or BS with 5+ years’ experience
- Technical/Functional (Line) Expertise (Breadth and depth of knowledge, application and complexity of technical knowledge)
- Experienced in the design, development and implementation of in vitro cell based functional assays to study target-specific drug effects
- Knowledge and experienced in cell biology and antibody characterization
- Experience with cell based functional assay platforms including, but not limited to, on-cell binding, reporter assay, Alphalisa, MSD, flow cytometry, cell adhesion, cell migration, and imaging
- Experience in troubleshooting, assay optimization and data quality control is a plus
- Skilled in data analysis, interpretation, and data reporting
- Leadership (Vision, strategy and business alignment, people management, communication, influencing others, managing change)
- Excellent written and verbal communication skills, along with the ability to work with cross-functional project teams
- Ability to work independently and self-driven in managing and accomplishing daily tasks
- Decision-making and Autonomy (The capacity and authority to make organizational decisions, autonomy in decision-making, complexity of decisions, impact of decisions, problem-solving)
- Hands-on cell-based functional assay experience
- Ability to manages workflow to deliver quality results in timely manner
- Troubleshoots complex problems in creative and effective ways and actively participates in innovation and/or optimization of established processes to ensure data relevance and quality?
- Ability to make data-driven influences on projects decision making
- Interaction (The span and nature of one’s engagement with others when performing one’s job, internal and external relationships)
- Works well under minimal supervision
- Good interpersonal skills, collaborate with team members
- Participate in cross-functional project team interactions and collaborations
- Innovation (The required level of scientific knowledge, knowledge sharing, innovation and risk taking)
- Participates in new technology assessment under supervision
- Complexity (Products managed, mix of businesses, internal and/or external business environment, cultural considerations)
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