Contract Clinical Research Associate

2 weeks ago

Durham, United States Grove Technical Resources, INC Full time

Job Title - Junior Contract Research Associate

Job Location - Durham, North Carolina, and Columbus, Ohio (Fully Onsite)

Type: W2 contract


Job Description Summary:

The Contract Research Associate plans and conducts experiments under the direction of a Scientist I for in vitro studies and assay development to advance our portfolio of genetic therapies spanning Gene Therapy, RNA, and Gene Editing treating neuromuscular and CNS-related diseases. The contract research associate works as part of the team at our Genetic Engineering Innovation Center in Durham and with the broader research teams in Ohio and Massachusetts. Reporting structures may shift as the North Carolina site grows.


Primary Responsibilities Include:

Plans and conduct experiments at the direction of scientists, performs routine laboratory functions using a variety of assay formats such as molecular cloning, nucleic acid and protein purification, Western blot, PCR, next-generation sequencing, and coordinates activities and timelines through close collaboration with the laboratory head and other laboratory staff.

Contributes to a safe, efficient and effective laboratory environment with personal accountability; equipment procurement and maintenance, lab set up and maintenance; ordering of reagents, glass and plastic-ware kits and equipment to keep the laboratory stocked and functional.

Participate in evaluation and implementation of new technologies to improve quality and robustness of sample analysis.

Troubleshoots routine technical challenges and contributes to their resolution.

Maintains compliant laboratory records, authors technical documents, protocols and reports; ensures effective high quality timely and appropriate documentation in laboratory notebooks and internal technical reports following Good Documentation Practices (GDPs).

Performs other related duties as assigned.


Desired Education and Skills:

B.S. degree in a scientific discipline with 3-5 years of relevant experience in a laboratory setting, including one year in molecular biology research, neuromuscular disease research and/or gene therapy research or development.

Demonstrated mastery of basic laboratory methods working with attention to detail and high standards for data integrity and quality.

Proven experience with a variety of analytical techniques, methods of development and validation.

Ability to execute sample handling, testing, data management and data analysis with strict adherence to Good Laboratory Practices and SOPs.

Knowledge of RNA biology and gene expression analysis. Experience with DNA/RNA purification, PCR, immunofluorescence (IF) staining and imaging, and Western blot is preferred.

Desire to work in a high-functioning, collaborative team.

Experience with computer productivity software (i.e. Word, Excel, etc.).

Excellent written and verbal communication skills.

Desire to work in a dynamic, fast-paced team environment and to make a difference in the lives of people through our innovative medicines.

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