Formulation Scientist
3 days ago
Duties:
Client is seeking an exceptional candidate to contribute to preformulation research in a small, fast-paced and highly collaborative team. This temporary position resides within the Formulations Sciences group of Technical Operations in the Non-clinical Development Sciences organization. The candidate will contribute to the execution of laboratory activities related to the transition of Client small molecule compounds from Discovery into Development in support of Client pre-clinical and clinical programs. An ideal candidate will have a strong foundation in analytical techniques such as UPLC/HPLC (Empower proficiency is desired but not required) and dissolution, and an understanding of early drug development processes and experiments. Experience in preformulation development and physicochemical characterization is desired, however not required.
Candidate should have 2+ years’ experience working in pharmaceutical sciences (preformulation, analytical or formulation development).
Responsibilities:
Prepare buffers and common lab solutions
Execution of experiments with XRPD, DSC, TGA, DVS, optical microscopy and UPLC/HPLC (Empower)
Screen excipients/formulation vehicles and optimize preclinical formulations to enable non-GLP and GLP pre-clinical studies
Perform drug substance and formulation stability studies to ensure optimal formulation design
Coordinate vehicle/formulation preparation for in vivo studies
Execute dissolution studies to support formulation development and FIH development
Maintain an accurate, timely, and compliant laboratory notebook
Education:
Qualifications:
degree in chemistry, analytical chemistry, pharmaceutics, chemical engineering or material sciences with 2+ years’ experience
Experience in the Discovery and Development interface
Experience working with common excipients and volumetric glassware
Proficiency with UPLC/HPLC and Empower Software (not required)
Knowledge of small molecule and pre-clinical formulation development (not required)
All applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.
WHO WE ARE:
***’ mission is to dramatically improve the lives of patients with genomically defined diseases. Our singular focus is to use our deep understanding of the genetic blueprint of cancer and other diseases driven by the abnormal activation of kinases to craft highly selective medicines aimed at eradicating these diseases.
We don’t think in small steps. We think in giant leaps.
We are driven by the pursuit of new ideas, new innovations, and new ways of thinking.
We know that what each and every one of us does matters and that our success depends on our ability to work together. We believe we are at our best as a company when our employees are thriving and foster a culture that provides opportunities to grow and develop professionall
Languages:
English( Speak , Read , Write )
Skills:
Capabilities:
Ability to effectively prioritize and manage multiple tasks and compounds
Self-motivated and willing to “learn on the job” and ask for assistance when needed
At home in a results-driven, highly accountable environment where you can make a clear impact
A team player, who listens effectively and invites response and discussion
A collaborator who communicates in an open, clear, complete, timely and consistent manner
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