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Senior Research Associate, Protein Sciences
3 months ago
This is a six month contract with either opportunity to extend or convert to FTE. Expectation is 40-hours a week.
About the Opportunity:
Client is seeking an outstanding, highly motivated individual to support protein production for our discovery programs. The successful candidate will be a member of the Protein Sciences team and support protein production utilizing mammalian protein expression, purification, and characterization. This position offers excellent potential for contribution and visibility at an early-stage company and opportunities for career development.
Role and Responsibilities:
- As an integral member of the Protein Sciences group, this individual will work closely with other team members and partner with other functional areas in the organization
- Production of proteins for Research and pre-clinical activities
- Protein expression in mammalian system in transient and stable format
- Protein purification using affinity and other chromatography methods
- Cryopreservation of cell lines and clarification of production medium
- Protein quantification, SDS-PAGE, size exclusion HPLC, other analytical methods as appropriate
- Materials management and inventory maintenance
- Maintenance of electronic lab notebook and databases, preparation of reports, and regular presentations to summarize results and update management
Education, Experience and Qualification Requirements:
- BS degree in biological sciences (biochemistry, cell biology, molecular biology) with 1-3 years experience in the biopharmaceutical industry
Core Competencies, Knowledge and Skill Requirements:
- Familiarity with mammalian protein expression systems in transient and stable formats, protein purification of monoclonal antibody and other proteins using affinity and other chromatography techniques
- Proficiency in aseptic technique, cell line maintenance, and host cell transfection
- Experience with analytical methods such as SDS-PAGE, size exclusion HPLC, ELISA, Octet and other methods for protein characterization
- Capacity for learning new techniques and handling diverse tasks concurrently
- Ability to collaborate and communicate well with colleagues
- Ability to work independently or with limited direct supervision
- The ideal candidate will be meticulous, highly organized, pay great attention to detail, deliver consistent results, and work under aggressive timelines
- The ideal candidate will have strong technical aptitude for lab and instrument work, and a problem-solving mindset that is diligent and flexible
