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Clinical Laboratory Technologist

2 months ago

Waltham, United States BostonGene Full time

About BOSTONGENE

BostonGene Corporation is pioneering the use of biomedical software for advanced patient analysis and personalized therapy decision-making in the fight against cancer. BostonGene’s unique solution performs sophisticated analytics to aid clinicians in evaluating viable treatment options for each patient’s individual genetics, tumor and tumor microenvironment, clinical characteristics, and disease profile. BostonGene’s mission is to enable physicians to provide every patient with the highest probability of survival through optimal cancer treatments using advanced, personalized therapies via sophisticated analytics and the integration of scientific and clinical knowledge.


Position Summary

The Clinical Laboratory Technologist will be responsible for performing high-complexity molecular testing according to established SOPs, including DNA and RNA extractions, NGS library preparation, hybridization-based enrichments, and next-generation sequencing.

SHIFT: Tuesday - Saturday, 11am - 7pm


Responsibilities

  • Under supervision, operate quantification, sizing, liquid handling, and NGS instruments.
  • Perform daily, weekly, monthly, and as-needed equipment maintenance checks.
  • Order and maintain adequate supplies of all reagents and consumables.
  • Participate in reagent and assay quality control and validations.
  • Demonstrate commitment to quality and continuous improvement.
  • Perform workflow that maintains quality, thoroughness, and optimum efficiency for Turn Around Time (TAT).
  • Utilize the Laboratory Information Management System (LIMS) to track and execute sample processing.
  • Document and maintain records and data for executed process steps per Good Documentation Practices (GDP).
  • Participate in additional continuous quality improvement activities.
  • Adhere to safety protocols, such as wearing laboratory coats and required safety gear.
  • Maintain organization and cleanliness in the labs.
  • Collaborate on SOPs revisions and drafts as needed to adjust for process improvement initiatives and regulatory changes.
  • Contribute to quality improvement initiatives.
  • Support planning and execution of process development and improvement activities, including LIMS and automation projects.
  • Collaborate in updating SOPs.
  • Understanding of the process in troubleshooting assays and instrumentation as needed.
  • Demonstrate commitment to maintaining TAT objectives, quality, and continuous improvement.
  • Develop a close working relationship with the other technical and scientific staff while collaborating effectively with colleagues from other sections


Qualifications

  • 2+ years of relevant lab experience in a CLIA/CAP lab.
  • Working knowledge in a NGS (Next-Generation Sequencing) environment.
  • Bachelor of Science (BS) in Biological or Life Sciences.
  • Experience with ensuring and maintaining integrity and quality of the lab (sample processing, equipment, SOPs).
  • Ability to learn new tasks in appropriate timeframes.
  • Excellent attention to detail with experience following precise instructions.
  • Well-organized.
  • Excellent communication skills.
  • Proficiency in Laboratory Information Management System (LIMS).
  • Knowledge of laboratory safety protocols.