Sr. Manager, IT

4 weeks ago


Waltham, United States Upstream Bio Full time

Upstream Bio is developing innovative therapeutics in inflammation. We are a nimble company with solid financial backing that has raised $400M from high-quality investors. We are developing a monoclonal antibody targeting validated biology and are focused on our two Phase 2 studies in asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) 2024. Our offices are in Waltham, MA. We have a hybrid working model, with Tuesdays-Thursdays in the office and Mondays and Fridays flexible to work remotely if desired. This role may require on-site presence Mondays and Fridays depending on need.


This is a newly created technical, hands-on, and strategic role in the growing operations group at Upstream. The Senior Manager of IT will be accountable for further maturing and running the company’s IT systems supporting a variety of functions spanning mainly corporate but also supporting development functions as required. Upstream is adopting a modern, cloud-first strategy for most of its IT capabilities and is seeking a strong candidate to take ownership of the operations as well as manage its existing MSP relationship. This role will also oversee some facilities needs, which is currently an office-only environment and include supporting Upstream as it relocates in Waltham over the summer of 2024.


The focus for this role will be one of growth, especially in terms of new capabilities and the next stages of maturity of operations.


Key Responsibilities:

  • Focus on information security, balancing between usability and compliance
  • Interface with a variety of departments and stakeholders, including Finance, Business Operations, People & Culture and R&D
  • Automate strategies to minimize maintenance overhead
  • Manage vendors, including an outsourced team handling day-to-day helpdesk and system administration duties
  • Identify needs, taking initiative to prioritize security efforts as well as short term goals
  • Provide local support for on-site desktop users, A/V, printers, scanners, etc.


Qualifications:

  • Bachelor's degree in Computer Science, Information Technology, or a related field
  • 5+ years of experience managing a mission-critical IT operation
  • Ability to identify needs, take initiative, and prioritize security efforts and short-term goals
  • Comfortable working directly with C-level executives on strategic initiatives
  • Experience working in a highly regulated industry, especially biopharma
  • Experience with ITGCs and the SOX control environment
  • Service oriented and high level of discretion
  • Experience with facilities management, operations, and security of office space and equipment.


  • Waltham, United States Thermo Fisher Scientific Full time

    ThermoFisher Scientific Sr. Director Talent Management Waltham , Massachusetts Apply Now Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue exceeding $40 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving...


  • Waltham, United States Planet Pharma Full time

    Job Description: Playing a critical role , the Sr. Manager, GCP Quality Assurance will be relied upon as Subject Matter Expert in providing GCP Quality Assurance and Compliance support with respect to planning, execution and close-out of clinical programs. The Sr. Manager, GCP Quality Assurance coordinates GCP Compliance activities with Clinical Operations,...


  • Waltham, United States Planet Pharma Full time

    Job Description: Playing a critical role , the Sr. Manager, GCP Quality Assurance will be relied upon as Subject Matter Expert in providing GCP Quality Assurance and Compliance support with respect to planning, execution and close-out of clinical programs. The Sr. Manager, GCP Quality Assurance coordinates GCP Compliance activities with Clinical Operations,...


  • Waltham, United States Planet Pharma Full time

    Job Description: Playing a critical role , the Sr. Manager, GCP Quality Assurance will be relied upon as Subject Matter Expert in providing GCP Quality Assurance and Compliance support with respect to planning, execution and close-out of clinical programs. The Sr. Manager, GCP Quality Assurance coordinates GCP Compliance activities with Clinical Operations,...


  • Waltham, United States Sobi Full time

    Job Description Sobi is currently seeking a Sr. Manager, Financial Planning & Analysis to join our Finance team. This position is responsible for forecasting, variance analysis, business partnering with non-finance personnel and maintenance and design improvements to our financial planning system.  This occurs within a fast-paced and highly collaborative...


  • Waltham, United States Planet Pharma Full time

    Job Description:Playing a critical role , the Sr. Manager, GCP Quality Assurance will be relied upon as Subject Matter Expert in providing GCP Quality Assurance and Compliance support with respect to planning, execution and close-out of clinical programs. The Sr. Manager, GCP Quality Assurance coordinates GCP Compliance activities with Clinical Operations,...


  • Waltham, United States Planet Pharma Full time

    Job Description:Playing a critical role , the Sr. Manager, GCP Quality Assurance will be relied upon as Subject Matter Expert in providing GCP Quality Assurance and Compliance support with respect to planning, execution and close-out of clinical programs. The Sr. Manager, GCP Quality Assurance coordinates GCP Compliance activities with Clinical Operations,...


  • Waltham, United States Thermo Fisher Scientific Full time

    Work Schedule Standard (Mon-Fri) Environmental Conditions Office Job Description How you will make an impact: As Sr. Manager, Human Resources Business Partner you will act as a trusted strategic partner, talent champion and organizational development leader as part of the PSG Group HR team. In this role you will guide and take action in all aspects of HR...


  • Waltham, Massachusetts, United States Stratacuity Full time

    Sr CTM- Autoimmune Location: Waltham, MA (Hybrid)Therapeutic Area:Autoimmune Job Overview: The Senior Clinical Trial Manager will lead in providing trial management support for autoimmune immunotherapy programs, ensuring the preparation of study materials, managing relationships with study sites and vendors, supervising activities, planning for risks, and...


  • Waltham, United States Thermo Fisher Scientific Full time

    Work ScheduleStandard (Mon-Fri)Environmental ConditionsOfficeJob DescriptionHow you will make an impact:As Sr. Manager, Human Resources Business Partner you will act as a trusted strategic partner, talent champion and organizational development leader as part of the PSG Group HR team. In this role you will guide and take action in all aspects of HR lifecycle...


  • Waltham, Massachusetts, United States Thermo Fisher Scientific Full time

    Work ScheduleStandard (Mon-Fri)Environmental ConditionsOfficeJob DescriptionHow you will make an impact:As Sr. Manager, Human Resources Business Partner you will act as a trusted strategic partner, talent champion and organizational development leader as part of the PSG Group HR team. In this role you will guide and take action in all aspects of HR lifecycle...


  • Waltham, Massachusetts, United States Thermo Fisher Scientific Full time

    Work ScheduleStandard (Mon-Fri)Environmental ConditionsOfficeJob DescriptionHow you will make an impact:As Sr. Manager, Human Resources Business Partner you will act as a trusted strategic partner, talent champion and organizational development leader as part of the PSG Group HR team. In this role you will guide and take action in all aspects of HR lifecycle...


  • Waltham, United States Morphic Therapeutic Full time

    About Morphic TherapeuticMorphic Therapeutic is a biopharmaceutical company developing a new generation of oral integrin therapies for the treatment of serious chronic diseases, including autoimmune, cardiovascular and metabolic diseases, fibrosis and cancer. In collaboration with Schrödinger, Morphic is advancing its pipeline and discovery activities using...


  • Waltham, United States Morphic Holding, Inc. Full time

    Description About Morphic Therapeutic Morphic Therapeutic is a biopharmaceutical company developing a new generation of oral integrin therapies for the treatment of serious chronic diseases, including autoimmune, cardiovascular and metabolic diseases, fibrosis and cancer. In collaboration with Schrödinger, Morphic is advancing its pipeline and discovery...


  • Waltham, United States Healthcare Businesswomen's Association Full time

    About Morphic Therapeutic Morphic Therapeutic is a biopharmaceutical company developing a new generation of oral integrin therapies for the treatment of serious chronic diseases, including autoimmune, cardiovascular and metabolic diseases, fibrosis and cancer. In collaboration with Schrödinger, Morphic is advancing its pipeline and discovery activities...


  • Waltham, United States Healthcare Businesswomen's Association Full time

    About Morphic Therapeutic Morphic Therapeutic is a biopharmaceutical company developing a new generation of oral integrin therapies for the treatment of serious chronic diseases, including autoimmune, cardiovascular and metabolic diseases, fibrosis and cancer. In collaboration with Schrödinger, Morphic is advancing its pipeline and discovery activities...


  • Waltham, United States Morphic Holding, Inc. Full time

    Description About Morphic Therapeutic Morphic Therapeutic is a biopharmaceutical company developing a new generation of oral integrin therapies for the treatment of serious chronic diseases, including autoimmune, cardiovascular and metabolic diseases, fibrosis and cancer. In collaboration with Schrödinger, Morphic is advancing its pipeline and discovery...


  • Waltham, United States Morphic Holding, Inc. Full time

    Description About Morphic Therapeutic Morphic Therapeutic is a biopharmaceutical company developing a new generation of oral integrin therapies for the treatment of serious chronic diseases, including autoimmune, cardiovascular and metabolic diseases, fibrosis and cancer. In collaboration with Schrödinger, Morphic is advancing its pipeline and discovery...


  • Waltham, United States Morphic Holding, Inc. Full time

    Description About Morphic Therapeutic Morphic Therapeutic is a biopharmaceutical company developing a new generation of oral integrin therapies for the treatment of serious chronic diseases, including autoimmune, cardiovascular and metabolic diseases, fibrosis and cancer. In collaboration with Schrödinger, Morphic is advancing its pipeline and discovery...


  • Waltham, Massachusetts, United States Morphic Holding, Inc. Full time

    About Morphic TherapeuticMorphic Therapeutic is a biopharmaceutical company developing a new generation of oral integrin therapies for the treatment of serious chronic diseases, including autoimmune, cardiovascular and metabolic diseases, fibrosis and cancer. In collaboration with Schrödinger, Morphic is advancing its pipeline and discovery activities using...