Analytical Development Scientist

Found in: Appcast Linkedin GBL C2 - 2 weeks ago


Woburn, United States The Steely Group Full time

Our client is seeking an analytical chemistry scientist with a collaborative and innovative mindset to join our Analytical Development group in Woburn, MA.


Strong preference will be given to a candidate with proven experience in developing biophysical and analytical chemistry assays like SEC-MALS, HPLCs, CE-SDS, iCIEF as it relates to biologics and gene therapy products.


Reporting to the Associate Director of Analytical Development, the Scientist will be responsible for the development of biophysical and analytical chemistry methods to further gene therapy products throughout clinical development, as well as performing BLA-enabling characterization studies.


In this role you are encouraged to interact and collaborate across other functions within the company.


Responsibilities:


• Investigate and evaluate cutting edge biophysical and analytical instrumentation for AAV, AAV-Ab characterization.


• Develop methods to quantitatively measure the purity and heterogeneity of AAV gene therapy vectors, including empty capsid, aggregation, and capsid protein purity.


• Evaluate and implement new analytical platforms, such as Mass Photometry, SEC-MALS, and HPLC, to characterize AAV particles.


• Provide technical support to cross-function groups and external collaborators.



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