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Facilities Support Associate, Full Time

3 months ago


Boston, Massachusetts, United States Takeda Full time

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda'sPrivacy Noticeand Terms of Use.

I further attest that all information I submit in my employment application is true to the best of my knowledge.

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients.

By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.

The Process Research (PR) group within Synthetic Molecule Process Development (SMPD) is a global team responsible for interfacing with Takeda's Discovery functions (e.g.

medicinal chemistry, DMPK, Drug Safety) with the goal of route identification and phase appropriate route development to deliver GLP Tox and Ph 1 GMP Drug Substance (DS).

Join Takeda as an Associate Scientific Fellow, Process Research (PR) where you will play a crucial role in advancing our mission by pushing the boundaries of synthetic chemistry and driving innovation in drug development.

You will also work on stimulating scientific and technical challenges in a highly collaborative and empowering environment. As part of the SMPD team, you will report to Head, Process Research.

Our PR team within Synthetic Molecule Process Development (SMPD) engages deeply with the Takeda Research group todevelop phase appropriate processes for the manufacture of new synthetic molecule Drug Substance (DS) through Ph1.

We are committed to achieving and controlling the highest standards of purity and quality in all our products.
Analyzes and interprets scientific data independently.

Lead a DS team and serve as a global resource to design phase-appropriate strategies for reaction optimization, and scale-up demonstration, and conducts troubleshooting experiments to achieve project goals.

Connect with external scientific consortia and be a driveronnew technologies and trends in process chemistry and drug development, leading global PR integration of relevant advancements into project strategies.

Help global PR team maintain a current understanding of synthetic organic chemistry literature and technology trends/advancements.
Actively builds cross-functional and cross-site relationships and strategies in support of early-stage Pharmaceutical Sciences development.

Serves as a subject matter expert and collaborates with other Pharmaceutical Sciences functions (Analytical Development, Drug Product Development, etc.) and Takeda Research in support of the development and implementation of an overall CMC strategy.

Plays an important/key role in actively contributing to the development of a CMC strategy and related timelines (including Gantt charts) as a Drug Substance Lead, proactively balances risks against project needs, and communicates progress and related plans in a timely and transparent manner.

The opportunity to lead a cross-functional CMC team consisting of Drug Substance Development (SMPD), Analytical Development, Drug Product Development, and adjacent functions (such as QC, QA, CMC regulatory affairs, clinical supply chain) with full accountability for the CMC strategy and its successful execution.

Identifiesglobal SMPD and cross-departmentalopportunities for strategic initiatives and leads global department initiatives with accountability for performance and results. Communicates efforts with senior management of other functions as appropriate.
Bachelor's degree in chemistry and 15+ years relevant industry experience.
PhD in chemistry and7+ years relevant industry experience.
Extensive experience in CMC pharmaceutical development for active pharmaceutical ingredients and drug products under cGMP's.
Previous experience with the use of contract facilities.
documents issues and/or concerns concisely with colleagues; technical writing skills to support authorship of internal technical documents.

Understanding of a wide range of synthetic organic chemistry, including reaction mechanistic aspects and synthetic route design (retrosynthetic analysis), paired with excellent laboratory and productivity skills.

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do.

We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

No Phone Calls or Recruiters Please.

The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

S. based employees may be eligible for short-term and/or long-termincentives.

S.based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others.

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Full time