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Formulations Scientist

2 months ago

Mountain View, United States Turn Biotechnologies, Inc. Full time

Company

Based in Mountain View, California, Turn Biotechnologies, Inc. is a development-stage company focused on restoring cells’ youthful vigor to repair damage caused by the aging process. Using a proprietary ERA™ Platform, we develop mRNA medicines that are specially formulated to instruct specific cells in the body to fight disease or repair damaged tissue. We do this by reprogramming the epigenome to restore cell function that people often lose as they age. This approach can be used to revitalize different cells throughout the body. We are researching its applicability across multiple therapeutic areas, including dermatologic conditions, pulmonary disease, osteoarthritis, and ophthalmology.

Responsibilities

Essential duties include but are not limited to:

Assisting with the design and execution of LNP development projects

Learning and utilizing cutting-edge development and preparation methodologies/techniques to design and execute efficient LNP formulation processes

Designing, preparing and characterizing formulations using a variety of techniques

Assisting with the development and scale of new technologies

Maintaining the lab instruments used in the lipid formulation group’s work

Applying good documentation practices consistently while working

Recording information accurately into various databases

Reviewing data with an eye towards recognizing and reporting inconsistencies to supervisor

Maintaining all appropriate corporate standards for lab safety and hazardous material management

Performing daily operations with an approach designed to minimize risks and hazardous waste streams

Maintaining a lab notebook, instruments, and inventory records in accord with department guidance and regulatory requirements.

QUALIFICATIONS

Required Qualifications

Bachelor’s or Master’s with 3-5 years prior experience or Ph.D., with degree in chemistry biochemistry, biophysics, or related field

Prior experience in Lipid Nanoparticles formulations is a must.

Hands-on experience on characterization techniques for LNPs.

Prior hands-on experience with at least one of the following analytical tools: High Performance Liquid Chromatography (HPLC), Ultra-Centrifugation, or filtration methods of macromolecules or biologics

Brings an enthusiastic, hands-on approach to laboratory science while applying subject matter expertise to experimental results

Exhibits a willingness to learn and is eager to apply new techniques and procedures

Desire to be hands-on

Strong and independent problem-solving and troubleshooting abilities

Preferred, Not Required Qualifications

A good understanding of the drug discovery and development process

Experience in developing liquid, semi-liquid, Gel-like and solid LNP formulations

Able to work independent and capably in scenarios requiring multi-tasking and prioritization

Experience developing preclinical formulations to support efficacy and tox studies

Experience with Sterile formulation preparation.

Experience profiling particles light-scattering techniques

Experience with structure or composition determination using LCMS

Experience maintaining thorough and timely documentation of experiments in laboratory notebooks

Prior experience developing drug products in dermatology, osteoarthritis, or ophthalmology is a plus

Desirable Characteristics

Excellent organizational, oral, and written communication skills

Ability to work independently and with teams to achieve goals

Proficient in presenting data and results in group settings

Flexibility, with an ability to prioritize/accommodate work schedules as needed

Experienced writing scientific reports

Emotionally intelligent; a “whatever it takes” attitude

WHY TURN?

We are a close-knit, collaborative team, passionate about anti-aging, longevity, and improving the effects of age-related disease and the quality of people’s lives

Competitive compensation

Fully-paid employee medical, dental, vision, & life insurance benefits

401K

FSA

Flexible PTO

Employee Assistance Program

You will be a vital part of the company and tremendously impact its success.

Equal Opportunity Employer Statement: Turn Biotechnologies is an Equal Opportunity Employer that values and respects the importance of a diverse and inclusive workforce. We do not discriminate on the basis of race, color, religion, sex, age, national origin, veteran status, disability, genetic information, pregnancy, sexual orientation, or gender identity. We recognize that diversity and inclusion are driving forces for the success of our company.

Occupational Health and Safety: Turn Biotechnologies provides a workplace free from recognized hazards and complies with standards, rules, and regulations issued under the OSH Act.