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Scientist I

3 months ago

Redwood City, United States Codexis, Inc. Full time


Department
64 - QC & Analytical Development

Employment Type
Full Time

Location
Redwood City, CA

Workplace type
Onsite

DescriptionCodexis, a biotechnology company based in Redwood City, CA, is looking to hire a Scientist I - Analytical Development.
 Codexis is a leading enzyme engineering company leveraging its proprietary CodeEvolver® technology platform to discover, develop and enhance novel, high-performance enzymes and other classes of proteins. Codexis enzymes solve for real-world challenges associated with small molecule pharmaceuticals manufacturing and nucleic acid synthesis. The Company is currently developing its proprietary ECO Synthesis™ platform to enable the scaled manufacture of RNAi therapeutics through an enzymatic route. Codexis enzymes can drive improvements, such as higher yields, reduced energy usage and waste generation, improve efficiency in manufacturing and greater sensitivity in genomic and diagnostic applications.  

To meet the goals we’ve set for ourselves, we look for individuals who are driven, eager to grow and ready to embrace meaningful challenges. We empower employees to be authentic, ambitious, agile and have the courage to take action where they can make a positive impact. 

Come join us on this journey to transform the enzyme engineering landscape for the betterment of human health.

About the Opportunity: The Scientist I - Analytical Development will have an opportunity for collaborative interaction with process development and quality control to provide analytical support for our established biocatalyst and emerging RNA therapeutics businesses.  This role will be based in Redwood City, CA. If any of the below describes you, we would love to meet you

Strong problem-solving capabilities. Strong communication skills - both written and oral. Open to continuous learning in a fast-paced and collaborative environment.  Good time management skills.
In this role you will be responsible for: Develop and validate analytical methods for activity, purity, content and other quality attributes of pharma enzymes, life sciences enzymes, oligonucleotides, RNA-based therapeutics and other Codexis products.  Develop reliable analytical test methods following rigorous scientific methodology and industry standard application of ICH guidelines.  Design and execute physicochemical characterization, forced degradation and analytical studies on Codexis' products to support process development.  Perform data processing, evaluation and interpretation of test and experimental data, drawing conclusions based on the results.  Prepare test methods, protocols, summary reports and technical documentation.  Oversee method transfer, qualification and validation with Codexis partners in accordance with FDA and ICH guidelines.  Work with other project team members and communicate results with the team.  Conduct trouble shooting and lab investigations. 

The essential requirements of the job include: PhD in Analytical Chemistry, Chemistry, Biochemistry, or related discipline, OR MS in Analytical Chemistry, Chemistry, Biochemistry, or related discipline with 3+ years of experience in an cGMP or GLP analytical laboratory environment, OR BS in Analytical Chemistry, Chemistry, Biochemistry, or related discipline with 5+ years of experience in an cGMP or GLP analytical laboratory environment  Hands-on experience with analytical techniques and instrumentations and working knowledge of analytical method development and validation, such as enzyme kinetics, UV-Vis, RP-HPLC, IEX-HPLC, SEC, colorimetric and fluorescent plate-based assays, ELISA, qPCR, CE, SDS-PAGE, etc.  Strong attention to detail and good record documentation skills  Knowledge of ICH Quality Guidelines related to analytical method development/validation, impurities and stability
Additional experience that would be valuable for this role includes:

Experience working with enzymes and oligonucleotides/nucleic acids.  Strong theoretical understanding and hands-on experience with LCMS.
CODEXIS PAY TRANSPARENCY: The anticipated salary range for candidates who will work in Redwood City is $122,500 to $135,000. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etc. Codexis is a multi-state employer, and this salary range may not reflect positions that work in other states​.
What can Codexis offer you?Medical, Dental and Vision Insurance  Basic Life, AD&D, Short- and Long-Term Disability Insurance  401k with Company Match up to 4%  Company Equity  Generous Paid Time Off including 18 Company Holidays (with a summer and winter shutdown), Vacation, and Wellness Time  Annual Lifestyle Account for reimbursement of fitness programs, equipment and more  Employee Stock Purchase Program (ESPP)  Flexible Spending Accounts (Commuter/Parking, Dependent Care & Healthcare) Student Debt Program (Company Contribution to Loans) Mental Health Wellness Program Subsidized onsite lunch program Onsite Gym Facilities Paid Parental Leave And More

About Codexis Inc Why join Codexis?

At Codexis we offer a very competitive compensation package and beyond excellent benefits We foster career growth, continued education and upskilling through our mentorship program and learning and development opportunities. You will learn and work alongside inspirational leaders and colleagues who are equally passionate about our mission and committed to fostering an inclusive, growth-centered, and rewarding culture. Diversity is valued and mutual trust is of paramount importance to the ethos at Codexis. The people, the culture and working with others with a common goal is what makes Codexis a great place to work.

For more information, visit www.codexis.com.

NO AGENCIES OR THIRD PARTIES

Codexis is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status.