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Principal Scientist
4 months ago
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
Lilly’s Biotechnology Discovery Research (BioTDR) organization has a track record for delivering novel biotherapeutic medicines to advance into clinical research in key areas of unmet medical need including diabetes, oncology, immunology, neuroscience, and others.
Antibody display/engineering associate to join our Display Group responsible for the discovery of novel therapeutic antibodies. The successful candidate should possess solid general molecular biology, microbiology and laboratory skills and apply theoretical, technical and - if possible - hands-on expertise in display/discovery and engineering technologies to help evaluate, optimize and identify lead antibody molecules for clinical development.
Responsibilities
Support discovery and engineering efforts using emerging technologies for antibody display including affinity maturation
Execute antibody discovery and engineering strategies for lead identification and optimization
Run in-house processes for library construction for discovery, and perform library screening and selections
Independently perform complex experiments with attention to quality, detail and documentation
Interpret data, troubleshoot experiments and present work at internal meetings
Basic Qualification
Bachelor's degree in Biology or related field.
5+ years of experience in Antibody discovery and/or Engineering
Preferred Requirements/Skills
Knowledge and hands-on experience in library construction and/or screening
Experience with yeast, phage, RNA display and/or other discovery and molecular evolution technologies
Experience in FACS technology, applied to screening and selection activities
Prior work with antibody libraries, affinity maturation and antibody/protein engineering would be a plus
Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( Lilly_Recruiting_Compliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.
Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.
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