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Scientist 1, High Throughput Biology

4 months ago


Hayward, United States Eikon Therapeutics Full time

Eikon Therapeutics is a new biopharmaceutical company employing revolutionary technology at the intersection of chemistry, engineering, computation, and biology to discover novel treatments for life-threatening diseases. Eikon’s discovery platform is built on groundbreaking innovations from its founders (Nobel Prize, 2014), culminating in the creation of microscopes which enable real time, molecular-resolution measurements of protein movement in living cells, thereby unlocking otherwise intractable classes of proteins as drug targets.

Position 

As a member of the High-Throughput Biology Team, you will contribute to drug discovery screening campaigns using Eikon’s super-resolution microscopy platform. You will work closely with biologists, chemists, automation and software engineers to optimize cell-based assay at scale, execute and analyze high-throughput screens to generate actionable data.  

About You 

You are a highly motivated biologist with extensive experience in developing and executing high-throughput experiments, statistical analysis, data quality control, and interpreting complex data sets. Familiar with microscopy-based assays, you thrive in team environments and enjoy collaborating with people from diverse backgrounds. Known for your creativity, adaptability, and problem-solving skills in fast-paced settings, you possess excellent communication abilities and are conscientious, detail-oriented, and organized. You are committed to personal growth and eager to learn, driven to join an interdisciplinary team and push the frontier of drug discovery.

What You will Do 

Optimize and scale microscopy-based assays for HTS with an emphasis on robustness & reproducibility. Develop standardized procedures in close collaboration with other teams from the Research Operation department, to ensure robust screening activities.   Analyze large dataset using state-of-the-art computational and statistical methods, including machine learning.  Summarize key biological results to advance drug discovery efforts across an array of disease areas. Contribute to the growth and training of junior scientists. Collaborate and communicate across a diverse team of biologists, chemists, hardware and software engineers.  

Qualifications 

PhD degree; or master’s degree plus 10 years of relevant experience; or bachelor’s degree plus 12 years of relevant experience in cellular biology, biotechnology or related field. Working experience in an area of high-throughput biology: high-throughput assay, drug and/or genetic screen, or omics approaches. Experience with programming for large data analysis (python or R). Proficiency in mammalian cell culture, cellular and molecular biology. The ability to communicate clearly and build open collaborative relationships is essential. Working experience in quantitative microscopy and/or super resolution microscopy preferred. Experience in drug discovery, high throughput screens and hit characterization of small molecule compounds preferred. Experience with high-throughput instrumentation and automation systems preferred.  

At Eikon, employee compensation also includes bonus and equity compensation, in addition to several generous benefit programs, including:​

401k plan with company matching​ Medical (premiums covered by Eikon at 95%), dental and vision insurance (premiums covered by Eikon at 100%)​ Mental health and wellness benefits​ Weeklong summer and winter holiday shutdowns​ Generous paid time off and holiday policies​ Life/AD&D Insurance (premiums covered by Eikon at 100%) and optional supplemental employee-paid life/AD&D policies ​ Enhanced parental leave benefit​ Daily subsidized lunch program when on-site​

The expected salary range for this role is $109,000 to $118,750 depending on skills, competency, and the market demand for your expertise.

Eikon is proud to be an equal opportunity employer and will consider all qualified applicants for employment.

In accordance with the Company’s duty to provide and maintain a safe workplace, the Company requires all employees to be Fully Vaccinated with one of the FDA approved COVID-19 vaccines, which includes those vaccines that have received the FDA’s emergency use authorization. You will be expected to be Fully Vaccinated as of your Start Date. If you believe that you are exempt from this requirement under an applicable law or regulations, including Americans with Disabilities Act and California’s Fair Employment and Housing Act, you will need to contact the Company’s Human Resources group. For purposes of this section, Fully Vaccinated means (i) the completion of the vaccination regimen as approved by the FDA (by way of example, 2 doses of the Pfizer or Moderna vaccine and 1 dose of the Johnson and Johnson vaccine), and (ii) timely receiving booster vaccination, as recommended by the Centers for Disease Control and Prevention.

We are currently not accepting any new third-party agencies or firms at this time. Please do not forward unsolicited agency resumes to our website, employees or Human Resources. Eikon Therapeutics will not pay fees to any third-party agency or firm associated with unsolicited resumes.