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Senior Principal Scientist-Analytical R&D
4 months ago
Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.
At Pfizer, we are always seeking to deliver breakthroughs that change patients' lives. In this role, you'll be working to help us achieve that goal by advancing biotechnologicallyderived products to the market through innovation and delivery of cutting-edge analytical testing. You will be part of a team which is focused on developing methods and strategies to support product and process development for biotherapeutics and vaccines, including antibodies, antibody-drug conjugates and therapeutic proteins, at all stages of clinical development. You will work across analytical functions and projects and will also play a role in developing leaders and providing technical counsel to other organizations and senior leadership.
As a Senior Principal Scientist, you will be at the center of our operations and you'll find that everything we do, every day, is in line with an unwavering commitment to quality. You will be recognized as an outstanding scientist in your group. With your advanced knowledge of the discipline, you will regularly contribute in multi-disciplinary teams representing the department and influencing cross-functional teams. Your innovation is seen in way you promote the use of novel experimental approaches, create processes, hypothesesand methodologies. You will be using your scientific judgment to adapt standard methods and techniques by applying prior work experience. You will be entrusted with setting objectives and planning resource requirements for projects. You will undertake mentoring activities to guide team members.
It is your hard work and dedication that will make Pfizer ready to achieve new milestones and help patients across the globe.
Responsibilities
Apply technical and functional knowledge to design and independently execute experiments/projects, contributing to the overall direction of project.Technical areas anticipated: HPLC, LC-MS, dissolution, and spectroscopy (IR,NIR, Raman).
Act as a scientific resource within own sub-function/therapeutic area/discipline.
Develop appropriate drug product analytical control strategies that are aligned with program and regulatory expectations.
Provide technical and scientific leadership and represent analytical development on cross functional and cross-departmental program level teams.
Develop assay, qualification and transfer timelines which align with the program timelines.
Manage individual lab work on drug product candidates with a focus on developing the analytical methods and strategies to support the clinical and commercial aspects of product and process development and controls.
Encourage interaction and effective collaboration with project team members, including presenting data at project team meetings; critical review of data; and active involvement in solving technical challenges that arise during development.
Ensure that the staff has received appropriate training and that the training is current.
Keep abreast of scientific/ technological developments by participating in scientific meetings/ seminars and through regular scientific review.
Present experimental results at group meetings, project meetings and department meetings.
Responsible forthe analytical strategies for development of drug product candidates, which may include method development, release and stability testing, characterization and comparability analyses and analytical support for process and formulation development.
Serve as an analytical sciences resource for the department and project teams, proactively keeping colleagues updated with current scientific trends and technical aspects from conferences, local meetings and literature.
Qualifications
Doctoral Degree (PhD) in Analytical Science or similarand 7+ years of experience in drug product pharmaceutical development function.
Excellent written communication skills, including the ability to maintain an accurate.scientific notebook and draft concise written reports, publicationsand related documents.
Experienced with multiple software platforms and packaged, facilitating large data analytics and visualization.
Strong technical skills and scientific expertise in analytical method development and troubleshooting.
Additional analytical skills: NMR, particle characterization, forensic analysis preferred.
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Travel anticipated to be less than 10%
Additional Information
Relocation support available.
Work Location Assignment:On Premise
The annual base salary for this position ranges from $117,300.00 to $195,500.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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