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Modeling and Simulation Principal Statistician
3 months ago
Modeling and Simulation Principal Statistician is a biostatistician with solid experience in leading clinical trial design, execution, analysis and reporting; and excellent technical expertise in modeling and simulation. This role works closely with Director, Statistical Innovation (DSI), Strategic Development Director (SDD), EGTs and study teams throughout the evidence generation planning and study design process. This role is accountable for the development and execution of the simulation plan based on design options and simulation specifications provided by DSI, SDD and study teams; and deliver simulation reports under the guidance from DSI.
Participates in discussion sessions of EGP development and study design to ensure understanding of the clinical trial design options and collect design inputs from DSI, SDD and study team
Works with DSI to develop and finalize simulation plan with detailed specifications and operating characteristics that enable the evaluation and selection of the optimal design options
Executes simulation plan and summarizes results in outputs in presentation ready visualization
Works with DSI to evaluate design options and form design recommendations and finalize simulation report
Participates in sessions to present simulation results and recommendations to the product/study team
Leads the development of modeling and simulation tools
Supports the promotion of innovative designs and analysis methods by contributing to or providing internal training sessions
Provides training and team leadership to Modeling and Simulation junior statisticians when needed
Basic Qualifications
Doctorate degree and 2 years of Statistical Modeling and Simulation experience
OR
Master’s degree and 6 years of Statistical Modeling and Simulation experience
OR
Bachelor’s degree and 8 years of Statistical Modeling and Simulation experience
OR
Associate’s degree and 10 years of Statistical Modeling and Simulation experience
OR
High school diploma / GED and 12 years of Statistical Modeling and Simulation experience
Preferred Qualifications
Master’s degree in Statistics/Biostatistics or related subject with high statistical content with 6 years of post-graduate statistical experience in the biopharmaceutical industry in clinical trial design, execution, analysis and reporting; or
Doctorate in Statistics/Biostatistics with 4 years of post-graduate statistical experience in the pharmaceutical industry or medical research
Experience in designing, analyzing and reporting of clinical trials within Pharmaceutical/Biotechnology/Public Health setting in Industry, Government or Academia
Excellent computing, modelling and simulation skills using R, SAS, FACTS, etc.
Proactive and efficient in learning emerging adaptive designs and building simulation tools for wide use and applications
Independent work on project planning and execution
Knowledge of Bayesian statistics
Extensive knowledge of simulation and modeling techniques
Work well with both statistical colleagues and cross functional teams
Good communication skills (written and oral)
Thrive
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.
Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:
Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans and bi-annual company-wide shutdowns
Flexible work models, including remote work arrangements, where possible
Apply now
for a career that defies imagination
Objects in your future are closer than they appear. Join us.
careers.amgen.com
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position
Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.