Current jobs related to Principal Scientist, Preclinical Pharmacology - Boston - OSI
-
Principal Scientist, Preclinical Pharmacology
3 months ago
Boston, United States OSI Full timePrincipal Scientist, Preclinical PharmacologyPosition SummaryPepGen is seeking a highly motivated and innovative Principal Scientist to join the Preclinical Research and Development group in Boston, Massachusetts. We are looking for a senior scientist who brings enthusiasm, curiosity, scientific rigor, and a desire to transform the future of neuromuscular...
-
Principal Scientist, Preclinical Pharmacology
2 weeks ago
Boston, United States OSI Full timePrincipal Scientist, Preclinical PharmacologyPosition SummaryPepGen is seeking a highly motivated and innovative Principal Scientist to join the Preclinical Research and Development group in Boston, Massachusetts. We are looking for a senior scientist who brings enthusiasm, curiosity, scientific rigor, and a desire to transform the future of neuromuscular...
-
Principal Scientist, Preclinical Pharmacology
2 months ago
Boston, United States PepGen Full timePrincipal Scientist, Preclinical Pharmacology Position Summary PepGen is seeking a highly motivated and innovative Principal Scientist to join the Preclinical Research and Development group in Boston, Massachusetts. We are looking for a senior scientist who brings enthusiasm, curiosity, scientific rigor, and a desire to transform the future of neuromuscular...
-
Boston, Massachusetts, United States PepGen Full timeJob OpportunityPepGen is seeking a highly skilled and innovative Principal Scientist to join our Preclinical Research and Development team in Boston, Massachusetts. As a key member of our team, you will be responsible for leading the development, optimization, and execution of in vitro and in vivo nonclinical pharmacology studies.Key...
-
Boston, Massachusetts, United States PepGen Full timeJob OverviewPepGen is seeking a highly skilled and innovative Senior Research Scientist to join the Preclinical Research and Development group in Boston, Massachusetts. The successful candidate will be primarily responsible for the key aspects of the research and development, including pharmacology, of PepGen's Enhanced Delivery Oligonucleotide (EDO)...
-
Principal Scientist, Translational Medicine
6 days ago
Boston, United States Merck Full timeJob Description We have an exciting opportunity for a Principal Scientist (Director) in Translational Medicine. Translational Medicine at our Research Division is responsible for early clinical development of novel therapeutics, working in close collaboration with Discovery Sciences and late-stage Clinical Research. We work with all therapeutic areas within...
-
Quantitative Systems Pharmacology Modeler
4 weeks ago
Boston, Massachusetts, United States Takeda Full timeJob Title: Quantitative Systems Pharmacology Modeler - Scientist IIJob Summary:As a Quantitative Systems Pharmacology Modeler - Scientist II in DMPK & Modeling, you will be empowered to interface between clinical pharmacology, clinical research, nonclinical drug safety, drug discovery, drug metabolism, translational medicine and pharmacovigilance to...
-
Principal Clinical Pharmacology Expert
7 days ago
Boston, Massachusetts, United States Regeneron Pharmaceuticals Full timeJob SummaryWe are seeking a highly motivated Principal Scientist, Clinical Pharmacology to join our Pharmacometrics (PMx) group. The successful candidate will report to the Senior Group Director (SGD) within Clinical Pharmacology (CP) in the General Medicine (GM) group.Key ResponsibilitiesRepresent CP on project teams to provide strategic and scientific...
-
Boston, Massachusetts, United States Frontier Medicines Full timeJob Title: Senior/Principal Scientist, Disease BiologyFrontier Medicines is seeking a highly skilled and experienced Senior/Principal Scientist to join our Disease Biology team. The successful candidate will play a key role in leading the biology efforts aimed at elucidating drug mechanism of action and pharmacology on high-priority pipeline projects.Key...
-
Senior/Principal Scientist, Disease Biology
2 days ago
Boston, Massachusetts, United States Frontier Medicines Full timeJob DescriptionFrontier Medicines is seeking a highly motivated individual to fill the position of Senior or Principal Scientist to join our Disease Biology team. The successful candidate will play a leading role in leading the biology efforts aimed at elucidating drug mechanism of action and pharmacology on a high priority pipeline first-in-class projects....
-
Principal Scientist, Translational Bioinformatics
2 months ago
Boston, United States Pyxis Oncology Full timePosition: Principal Scientist, Translational Bioinformatics Hiring Manager: Head of Translational Medicine Location: Local to Boston, MA or Remote US Travel: [If Remote] Up to 20% of domestic travel Position Summary: Pyxis Oncology (‘PYXS’ or ‘Company’) is seeking an innovative, methodical and collaborative Principal Scientist, Translational...
-
boston, United States HireMinds Full timeSr. Scientist, Translational ImmunopharmacologyLocation: Boston, MassachusettsHireMinds is seeking your talent as a Senior Scientist with expertise in immunology and translational pharmacology to support the development of novel therapeutic approaches targeting immune regulation. In this role you’ll focus on regulatory T cell biology and autoimmunity,...
-
Boston, United States HireMinds Full timeSr. Scientist, Translational ImmunopharmacologyLocation: Boston, MassachusettsHireMinds is seeking your talent as a Senior Scientist with expertise in immunology and translational pharmacology to support the development of novel therapeutic approaches targeting immune regulation. In this role you’ll focus on regulatory T cell biology and autoimmunity,...
-
boston, United States QLD Biotherapeutics Inc Full timeFunction: Research & DevelopmentJob Title: Associate Scientist/Scientist, In Vivo PharmacologyJob Location: Boston Job SummaryAt QLD Biotherapeutics, we use cutting-edge Cell and Gene therapy technologies for the treatment of devastating diseases, including AD, PD, diabetes, tumors, and obesity. We are seeking a highly motivated individual to join...
-
Boston, United States QLD Biotherapeutics Inc Full timeFunction: Research & DevelopmentJob Title: Associate Scientist/Scientist, In Vivo PharmacologyJob Location: Boston Job SummaryAt QLD Biotherapeutics, we use cutting-edge Cell and Gene therapy technologies for the treatment of devastating diseases, including AD, PD, diabetes, tumors, and obesity. We are seeking a highly motivated individual to join...
-
Associate Scientist/Scientist, In Vivo Pharmacology
4 months ago
Boston, United States QLD Biotherapeutics Inc Full timeFunction: Research & DevelopmentJob Title: Associate Scientist/Scientist, In Vivo PharmacologyJob Location: Boston Job SummaryAt QLD Biotherapeutics, we use cutting-edge Cell and Gene therapy technologies for the treatment of devastating diseases, including AD, PD, diabetes, tumors, and obesity. We are seeking a highly motivated individual to join...
-
Boston, United States QLD Biotherapeutics Inc Full timeFunction: Research & DevelopmentJob Title: Associate Scientist/Scientist, In Vivo PharmacologyJob Location: Boston Job SummaryAt QLD Biotherapeutics, we use cutting-edge Cell and Gene therapy technologies for the treatment of devastating diseases, including AD, PD, diabetes, tumors, and obesity. We are seeking a highly motivated individual to join...
-
Associate Scientist/Scientist, In Vivo Pharmacology
4 months ago
Boston, United States QLD Biotherapeutics Inc Full timeFunction: Research & DevelopmentJob Title: Associate Scientist/Scientist, In Vivo PharmacologyJob Location: Boston Job SummaryAt QLD Biotherapeutics, we use cutting-edge Cell and Gene therapy technologies for the treatment of devastating diseases, including AD, PD, diabetes, tumors, and obesity. We are seeking a highly motivated individual to join...
-
Director of Preclinical Development, siRNA
4 weeks ago
Boston, United States Proclinical Staffing Full timeDirector of Preclinical Development, siRNA - Perm - Boston, MAProclinical is on the lookout for a dynamic and innovative individual to fill the role of Director, Preclinical Development. This role presents a unique opportunity to lead our Preclinical Development team, overseeing the design and execution of preclinical projects for RNAi therapeutic programs....
-
Director of Preclinical Development, siRNA
4 weeks ago
boston, United States Proclinical Staffing Full timeDirector of Preclinical Development, siRNA - Perm - Boston, MAProclinical is on the lookout for a dynamic and innovative individual to fill the role of Director, Preclinical Development. This role presents a unique opportunity to lead our Preclinical Development team, overseeing the design and execution of preclinical projects for RNAi therapeutic programs....
Principal Scientist, Preclinical Pharmacology
3 months ago
Principal Scientist, Preclinical Pharmacology
Position Summary
PepGen is seeking a highly motivated and innovative Principal Scientist to join the Preclinical Research and Development group in Boston, Massachusetts. We are looking for a senior scientist who brings enthusiasm, curiosity, scientific rigor, and a desire to transform the future of neuromuscular and neurodegenerative diseases. The successful candidate will be primarily responsible for the key aspects of the research and development, including pharmacology, of PepGen's Enhance Delivery Oligonucleotide (EDO) programs and future pipeline product candidates as well as interfacing with PepGen's external contract research organization (CRO) partners. Further, the successful candidate must be able to effectively multitask, manage scientists, have strong documentation skills, and should be comfortable working in multidisciplinary, cross–functional teams.
Responsibilities
Establish in vitro and in vivo pharmacology models and assaysIdentify CRO and academic partners for in vitro and in vivo pharmacology studies and establish collaborationsLead the development, optimization, and execution of in vitro and in vivo nonclinical pharmacology studies and implement rigorous data analysis techniques to elucidate pharmacodynamic effects.Manage nonclinical development studies for PepGen's enhanced delivery oligonucleotides to support pre–candidate and early and late development programs in–house and at CROs/academic institutesPartner with Research Project Team leaders, CMC, Toxicology, Bioanalytical, and Biomarkers functions in the design and interpretation of nonclinical pharmacology and efficacy studies as they relate to assessment of PK/PDManage associate scientists and scientific team membersMaintain clear technical records and prepare summary presentations and reports of ongoing activities for both internal and external audiencesFoster a culture of collaboration, innovation, discovery, and cutting–edge research culture focused on scientific excellence, open communication, and continual improvementRequirements
PhD in biomedical science, biochemistry, biology, or related discipline with at least 6+ years of relevant experience in the pharmaceutical industry in preclinical drug discovery and developmentExperience with in vitro and in vivo preclinical disease models and developing medium– to–high–through put assay formats to support drug developmentProficient in techniques, including method development and optimization, critical for molecular and cellular biology experiments e.g., protein and nucleic acid extraction and gene expression analysis by RT–PCR, qPCR and/or digital PCR, western blotting, and ISHExperience with managing and/or conducting studies with CROsDemonstrated experience and expertise in skeletal and/or cardiac muscle biologyExperience working with cell penetrating peptides, nucleic acids, and/or oligonucleotides conjugates in drug discovery and development is a plusHighly motivated scientist with ability to multitask and prioritize work. Demonstrate ability to thrive in a fast–paced environment and working within timelinesProven ability to work independently, think strategically and be self–motivatedExcellent interpersonal skills, ability to work in a matrix environment and develop relationships with key stakeholdersExcellent communication and presentation skills to efficiently relay information to project teams, senior management teamExperience working with external contract labs is essentialExperience with GxP is a plusExperience working in a start–up or small biotech environment is a plusAbout PepGen
PepGen Inc. is a clinical–stage biotechnology company advancing the next–generation of oligonucleotide therapies with the goal of transforming the treatment of severe neuromuscular and neurological diseases. PepGen's Enhanced Delivery Oligonucleotide, or EDO, platform is founded on over a decade of research and development and leverages cell–penetrating peptides to improve the uptake and activity of conjugated oligonucleotide therapeutics. Using these EDO peptides, we are generating a pipeline of oligonucleotide therapeutic candidates that target the root cause of serious diseases. For more information, visit or follow PepGen on Twitter and LinkedIn.
EEO Statement
PepGen is an Equal Opportunity Employer committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status.
Note:This role is 50% in lab.
Recruitment & Staffing Agencies
PepGen does not accept unsolicited agency resumes. Currently, we are working exclusively with The Bowdoin Group for all our recruiting needs. Thank you.
