Director, Medicinal Chemistry

Found in: beBee S US - 2 weeks ago


Cambridge, United States Foghorntx Full time
  • The Director, Medicinal Chemistry will devise and implement medicinal chemistry strategies to advance chemical matter through all stages of drug discovery, from hit ID to DC nomination.
  • Plan, prioritize and implement synthetic and medicinal chemistry strategies to achieve project goals
  • Collaborate with functional leads – e.g., computational chemistry, biology, crystallography, DMPK, pharmacology – to design appropriate flowcharts and drive program strategy
  • Apply advanced medicinal chemistry principles to design high quality compounds, considering multiple parameters in parallel – e.g., potency, selectivity, SBDD, ADME/PK, physicochemical properties
  • Provide clear communication of the medicinal chemistry strategy to cross-functional colleagues, scientific leadership and external collaborators, and present updates to key stakeholders – e.g., Leadership Team, Board of Directors
  • Master’s or PhD degree in organic chemistry, in addition to 10+ years of medicinal chemistry experience (14+ years for master’s) in a corporate pharmaceutical / biotechnology setting
  • Established leadership in drug discovery with proven track record of solving complex, multiparametric medicinal chemistry challenges
  • Ability to collaborate across disciplines and integrate cross-functional data to drive medicinal chemistry strategies

  • Director, Medicinal Chemistry

    Found in: beBee jobs US - 2 weeks ago


    Cambridge, Massachusetts, United States Foghorntx Full time

    The Director, Medicinal Chemistry will devise and implement medicinal chemistry strategies to advance chemical matter through all stages of drug discovery, from hit ID to DC nomination.Plan, prioritize and implement synthetic and medicinal chemistry strategies to achieve project goalsCollaborate with functional leads – e.g., computational chemistry,...

  • DIRECTOR, MEDICINAL CHEMISTRY

    Found in: Careerbuilder One Red US C2 - 2 hours ago


    Cambridge, MA 02138, USA, United States Foghorn Therapeutics Inc. Full time

    Our Culture: Why work with us?At Foghorn Therapeutics, we believe in People First, Mission Always.We put People First because we know our people are the key to everything we will accomplish. We value the diversity of background, ideas, perspectives and experiences that our team members bring to Foghorn Therapeutics - demonstrated by our community speaking...

  • Senior Scientist, Medicinal Chemistry

    Found in: beBee S US - 2 weeks ago


    Cambridge, United States Relay Therapeutics Full time

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  • Senior Scientist, Medicinal Chemistry

    Found in: beBee jobs US - 2 weeks ago


    Cambridge, Massachusetts, United States Relay Therapeutics Full time

    We are looking for a self-motivated, creative, and experienced medicinal chemist to join our team and help drive projects from lead generation through candidate selection in a fast-paced, highly collaborative environment.Be an integral part of a multi-disciplinary lead optimization team (alongside pharmacologists, computational chemists, biophysicists, and...


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  • Principal Scientist, Medicinal Chemistry

    Found in: beBee jobs US - 3 days ago


    Cambridge, Massachusetts, United States MOMA Therapeutics Full time

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    Found in: Resume Library US A2 - 2 weeks ago


    Cambridge, Massachusetts, United States Biogen Full time

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    Found in: beBee S US - 1 week ago


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    Found in: Appcast US C2 - 4 days ago


    Cambridge, United States Alkeus Pharmaceuticals, Inc. Full time

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  • Director / Senior Director, Process Chemistry

    Found in: Appcast Linkedin GBL C2 - 4 days ago


    Cambridge, United States Alkeus Pharmaceuticals, Inc. Full time

    About Alkeus Pharmaceuticals:Alkeus Pharmaceuticals, Inc. is a late-stage biopharmaceutical company developing transformative therapeutics to address serious, progressive eye diseases that lead to blindness. Our lead compound, gildeuretinol (ALK-001), is an oral investigational drug being developed for the treatment of Stargardt disease (STGD) and Geographic...

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    Found in: beBee S US - 2 weeks ago


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    Found in: beBee S US - 1 week ago


    Cambridge, United States MOMA Therapeutics Full time

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    Found in: beBee jobs US - 3 days ago


    Cambridge, Massachusetts, United States MOMA Therapeutics Full time

    MOMA Therapeutics is looking for an experienced Sr. Scientist/Principal Scientist, Computational Chemistry About MOMA TherapeuticsUnlocking a new target class in drug discovery is no small task: it requires computation to transform data into insights; it requires scientific and technological excellence; it demands a culture of focus, resilience, creativity,...


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    Our client is a pre-IPO oncology therapeutics company poised for rapid growth as they progress their lead candidate in the clinic to later stage development. They are seeking an experienced Process Chemist to join their growing Pharmaceutical Development group in the Cambridge/Lexington area. Reporting to the Vice President, the main function of this role...


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    Our client is a pre-IPO oncology therapeutics company poised for rapid growth as they progress their lead candidate in the clinic to later stage development. They are seeking an experienced Process Chemist to join their growing Pharmaceutical Development group in the Cambridge/Lexington area. Reporting to the Vice President, the main function of this role is...


  • Cambridge, United States MOMA Therapeutics Full time

    Job DescriptionJob DescriptionMOMA Therapeutics is looking for an experienced Sr. Scientist/Principal Scientist, Computational Chemistry About MOMA TherapeuticsUnlocking a new target class in drug discovery is no small task: it requires computation to transform data into insights; it requires scientific and technological excellence; it demands a culture of...

  • Director of Data Science

    Found in: beBee jobs US - 2 weeks ago


    Cambridge, Massachusetts, United States Novartis Full time

    AI & Computational Sciences, Novartis Biomedical Research Leadership Role in Chemistry-based AI/Machine LearningThe AI & Computational Science (AICS) team at Novartis Biomedical Research is dedicated to revolutionizing drug discovery through AI. Our mission is to accelerate the development of transformative medicines for patients worldwide.AICS is seeking a...


  • Cambridge, United States QurAlis Full time

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    Found in: Appcast US C2 - 1 week ago


    Cambridge, United States QurAlis Full time

    ABOUT THE COMPANY QurAlis is a clinical-stage biotechnology company developing breakthrough precision medicines for amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases with genetically validated targets.  QurAlis is trailblazing the path to conquering amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases with...

  • Director of Drug Substance Manufacturing

    Found in: Appcast Linkedin GBL C2 - 2 weeks ago


    Cambridge, United States QurAlis Full time

    ABOUT THE COMPANY QurAlis is a clinical-stage biotechnology company developing breakthrough precision medicines for amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases with genetically validated targets.  QurAlis is trailblazing the path to conquering amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases with...