Senior Scientist

2 weeks ago

Thousand Oaks, United States Amgen Full time

HOW MIGHT YOU DEFY IMAGINATION?

You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

Senior Scientist

Live

What you will do

Let’s do this. Let’s change the world. In this vital role you will join the Structural Biology Department at our site in Thousand Oaks, CA. The Structural Biology laboratory provides comprehensive molecular insights and structure-based design for drug-target assessment, mechanism of action, protein-protein and protein-ligand interactions, as well as protein engineering to facilitate drug discovery across various therapeutic areas.

  • Structure determination of target molecules in our small molecule induced proximity platform (IPP) using X-ray crystallography and/or cryo-electron microscopy (cryo-EM)

  • Work closely with molecular biologists and protein biochemists in the protein expression group

  • Collaborate with small molecule scientists including computational scientists, medicinal chemists, and protein engineers

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a scientist with these qualifications.

Basic Qualifications:

  • Ph.D. with a deep understanding of structural biology and general biochemistry

  • Significant post-doctoral research experience in large macromolecular complex structure determination. Knowledge of state-of-the-art protein structural biology techniques including all aspects of construct design, expression, purification, characterization, structure determination and analysis

  • Proven expertise on protein crystallography and/or cryo-EM single particle analysis, to determine atomic resolution structures

  • Experience with ubiquitin-proteasome system for protein degradation

  • Excellent presentation skills (written and oral) for effective team-based communication of results.

  • Ability to work independently and effectively within timelines and to collaborate in a multidisciplinary environment.

  • Skills in managing multiple projects and capability to prioritize.

Preferred Qualifications:

  • Experience with other protein biochemical and/or biophysical characterization of protein complexes

Thrive

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

  • Stock-based long-term incentives

  • Award-winning time-off plans and bi-annual company-wide shutdowns

  • Flexible work models, including remote work arrangements, where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

careers.amgen.com

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

  • Senior Principal Scientist

    2 weeks ago

    Thousand Oaks, California, United States Amgen Full time

    Senior Principal Scientist - PKDMCareer Category: ResearchJob Description:At Amgen, we're driven by a shared mission to serve patients. As a Senior Principal Scientist - PKDM, you'll play a vital role in our research team, focusing on small molecule (SM) programs. Your expertise will help us understand the absorption, distribution, metabolism, excretion...

  • Senior Principal Scientist

    2 weeks ago

    Thousand Oaks, California, United States Amgen Full time

    Senior Principal Scientist - PKDMCareer Category: ResearchJob Description:At Amgen, we're driven by a shared mission to serve patients. As a Senior Principal Scientist - PKDM, you'll play a vital role in our research team, focusing on small molecule (SM) programs. Your expertise will help us understand the absorption, distribution, metabolism, excretion...

  • Senior Scientist

    2 weeks ago

    Thousand Oaks, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION?Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology...

  • Senior Principal Scientist

    3 weeks ago

    Thousand Oaks, California, United States Amgen Full time

    Job Summary:As a Senior Principal Scientist at Amgen, you will serve as a functional representative and subject matter expert on the ADME/PK of small molecule therapeutics. You will collaborate with scientists across our PKDM scientific community to leverage your specialized knowledge and expertise.Key Responsibilities:Represent the PKDM function as a...

  • Senior Research Scientist

    3 weeks ago

    Thousand Oaks, California, United States Actalent Full time

    About the RoleWe are seeking a highly skilled and motivated Senior Research Scientist to join our team at Actalent. As a key member of our research team, you will be responsible for designing, conducting, and analyzing experiments to advance our engineering and science initiatives.Key ResponsibilitiesExperimental Design and Execution: Plan, conduct, and...

  • Process Development Senior Scientist

    3 weeks ago

    Thousand Oaks, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION?Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology...

  • Senior Scientist

    3 months ago

    Thousand Oaks, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION?Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology...

  • Senior Scientist

    4 weeks ago

    thousand oaks, United States ApTask Full time

    Scientist - Protein Mass Spectrometry, Molecular Analytics Experience using analytical characterization techniques such as RPLC-MS for intact protein, reduced and subunit protein mass analysis. Top skills: - Rapidfire-MS - Knowledge of multiple mass spectrometric (MassHunter, XCalibur, MassLynx) chromatographic (ChemStation, Chromeleon) control software is...

  • Senior Scientist

    4 weeks ago

    thousand oaks, United States ApTask Full time

    Scientist - Protein Mass Spectrometry, Molecular Analytics Experience using analytical characterization techniques such as RPLC-MS for intact protein, reduced and subunit protein mass analysis. Top skills: - Rapidfire-MS - Knowledge of multiple mass spectrometric (MassHunter, XCalibur, MassLynx) chromatographic (ChemStation, Chromeleon) control software is...

  • Process Development Senior Scientist

    3 weeks ago

    Thousand Oaks, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION? You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s...

  • Senior Biotechnology Research Scientist

    3 weeks ago

    Thousand Oaks, California, United States Amgen SA Full time

    About the RoleWe are seeking a highly skilled and experienced Senior Biotechnology Research Scientist to join our team at Amgen SA. As a key member of our Diagnostic Development Group, you will be responsible for developing and implementing global diagnostic development strategies to support our growing pipeline of precision therapeutics.Key...

  • Senior Biotechnology Research Scientist

    3 weeks ago

    Thousand Oaks, California, United States Amgen Full time

    Job SummaryWe are seeking a highly skilled and experienced Senior Biotechnology Research Scientist to join our team at Amgen. As a key member of our Diagnostics Group, you will be responsible for developing and implementing global diagnostic development strategies.Key ResponsibilitiesDevelop and implement end-to-end global diagnostic development strategies...

  • Senior Scientist Synthetic Chemistry

    1 month ago

    Thousand Oaks, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION?Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology...

  • Process Development Senior Scientist

    2 months ago

    Thousand Oaks, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION?Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology...

  • Senior Scientist

    3 months ago

    Thousand Oaks, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION?Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology...

  • Senior Scientist

    3 weeks ago

    Thousand Oaks, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION?Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology...

  • Process Development Senior Principal Scientist

    2 weeks ago

    Thousand Oaks, California, United States Amgen Full time

    Job Title: Process Development Senior Principal ScientistCareer Category: Process DevelopmentJob DescriptionAt Amgen, we're committed to serving patients by developing innovative treatments. As a Process Development Senior Principal Scientist, you'll play a critical role in leading our team in the development of sustainable and cost-effective processes for...

  • Sr. Principal Scientist

    3 weeks ago

    Thousand Oaks, United States Amgen SA Full time

    HOW MIGHT YOU DEFY IMAGINATION?If you feel like you’re part of something bigger, it’s because you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering...

  • Senior Principal Scientist

    3 weeks ago

    Thousand Oaks, California, United States Amgen Full time

    About the RoleWe are seeking a highly skilled and experienced Senior Principal Scientist to join our Commercial Drug Product Technologies Group in Thousand Oaks, CA. As a key member of our team, you will be responsible for providing technical and project leadership in the development and lifecycle management of commercial drug product formulation and...

  • Sr. Principal Scientist

    3 weeks ago

    Thousand Oaks, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION?If you feel like you're part of something bigger, it's because you are. At Amgen, our shared mission to serve patients drives all that we do. It is key to our becoming one of the world's leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering ever-better...