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Senior Scientist, BA

4 months ago


Waltham, United States AstraZeneca Full time
  • Senior Scientist, BA/DMPK (Oncology)
  • The Oncology Drug Metabolism and Pharmacokinetics department is looking for an individual who has a passion for BA and DMPK science, applied to Cancer biology.
  • As a BA scientist, you will provide drug discovery and development bioanalytical input and support for the analysis of in vivo PK, PD, and in vivo samples across the global Oncology portfolio.
  • In this role you will work closely with our established BA/ADME teams in Boston (US) and Cambridge (UK) to analyze and summarize data which will be presented in a multidisciplinary team environment.
  • Developing bioanalytical methods, analyzing biological samples using quantitative LC-MS/MS assays, and performing non-compartmental PK analysis (NCA).
  • Minimum of a BS degree in a relevant field with 1+ years of proven experience in industry or in a core bioanalytical lab.
  • Knowledge of the conduct and interpretation of a variety of in vitro DMPK assays.
  • Experience and knowledge of working with multiple modalities including; small molecules, biologics, Antibody Drug Conjugates (ADCs), nano-medicines and PROTACs is a plus.