Research Scientist II

Overview Applications to be submitted by October 31, 2025. Compensation Grade: P22. Compensation Details: Minimum: $81,696.00 – Maximum: $81,696.00 annually. Positions with a designated work location in New York City, Nassau, Rockland, Suffolk, or Westchester Counties will receive a $4,000 annual downstate adjustment (pro-rated for part-time positions). Department (OC) WADS – Wadsworth Center. Health Research, Inc. (HRI) is a dynamic non-profit organization partnering with the New York State Department of Health (DOH), Roswell Park Comprehensive Cancer Center (RPCCC), and other health-related entities to advance public health initiatives. HRI offers a comprehensive benefits package to eligible employees and is an Equal Opportunity Employer/Qualified Individuals with Disabilities/Qualified Protected Veterans. Responsibilities The Research Scientist II will join a new research laboratory that uses molecular genetic approaches to dissect mechanisms of fungal pathogenesis. The laboratory focuses on the fungal meningitis pathogen Cryptococcus neoformans, which causes 1 in 5 HIV/AIDS-related deaths worldwide and is the top-ranked World Health Organization Fungal Priority Pathogen. The incumbent will conduct research projects (planning, executing, and analyzing experiments) and will provide support to other laboratory members. This includes maintenance of a detailed laboratory notebook documenting all experiments, as well as proper archiving of all data and analyses. The incumbent will compile results from experiments for publications and presentations, and will contribute to training and mentoring of junior lab members. Additionally, the incumbent will contribute to establish protocols, databases, and inventories for a new research group. Experimental work will include, but is not limited to, molecular genetics (yeast/bacterial culture, molecular cloning, microbial transformation, CRISPR genome editing); generating and maintaining mutant strain libraries; protein biochemistry (protein purification; protein interaction studies; in vitro enzyme assays); and animal infection experiments. This position will be part of a dynamic team serving the Wadsworth Center’s mission in the New York State Department of Health’s efforts to protect and promote the health of New York’s citizens. Come be a part of Science in the Pursuit of Health® Minimum Qualifications Bachelor’s degree in a related field and three years of research experience; or a Master’s degree in a related field and two years of research experience; or a Doctorate in a related field. Preferred Qualifications Doctorate in microbiology, molecular biology, biochemistry, or a related field. At least five years’ research experience studying fungal cell and/or molecular biology. Strong publication record, including at least one high-quality, first-author primary research article (co-first authorship and manuscripts in review/revision that have been deposited to a preprint server are acceptable). Experience in microbial transformation, PCR, molecular cloning, protein purification, and protein interaction studies. Experience in constructing, maintaining, and performing genetic screens with complex microbial mutant libraries. Previous experience in murine infection models. Conditions of Employment Grant funded position. Compliance with funding requirements such as time and effort reporting, grant deliverables, and contract deliverables, is required. Visa sponsorship may be available for this position, in accordance with applicable federal requirements. Travel up to 10% of the time will be required. The incumbent in this position may be required to wear personal protective clothing and equipment. The selected candidate must reside within a reasonable commuting distance of the official work location specified in the job posting and must also be located in or willing to relocate to one of the following states: New York, New Jersey, Connecticut, Vermont, or Massachusetts, prior to hire. Telecommuting may be available on a very limited basis. HRI participates in the E-Verify Program. Affirmative Action/Equal Opportunity Employer/Qualified Individuals with Disabilities/Qualified Protected Veterans. #J-18808-Ljbffr