Postdoctoral Researcher
2 weeks ago
Job Summary
Lab of Dr. Prashant Rajbhandari in the Diabetes, Obesity, and Metabolism Institute (DOMI) has an opening for postdoctoral position. Rajbhandari Lab is broadly interested in 1) Immune cell regulation of lipid metabolism (Cell 2018), 2) developmental process of brown/beige and white fat, and 3) mammary gland adipose biology (Nature 2023), and 4) crosstalk between adipose and other metabolic tissues (esp liver) in the setting of obesity (Nature Medicine, Cell Metabolism 2017,2018). To address these topics, the lab uses cell and molecular biology, biochemistry, Next-gen sequencing (ChIP-, RNA-, ATAC-seq), animal model, single cell/nuclei RNA sequencing, and imaging. The broader significance of the work in Rajbhandari Lab is that obesity is linked to various diseases and by studying how cellular and molecular pathways are perturbed in the setting of obesity might provide better understanding of this disease.
We are looking for a Postdoctoral Fellow with a strong background in molecular and cellular biology, as well as protein biochemistry. The ideal candidate will have experience working with both cell culture and animal models. Experience in metabolism and epithelial cell biology is an advantage. The candidate should have completed their PhD within the last 1 to 1.5 years.
Please send CV to prashant.rajbhandari@mssm.edu. www.rajbhandarilabsinai.org
Essential Duties and Responsibilities
1. Advanced skills in Molecular Biology techniques
2. Advanced skills in cell biology, protein biochemistry, mass-spec, immunoblotting, immunohistochemistry, mRNA in situ hybridization, confocal imaging, cell culture, etc
3. Advanced skills in Animal handing and measuring metabolic physiology in mice
4. Mammalian cell culture techniques.
5. Animal handling, colony management, and genotyping
6. Eager to learn new techniques, operate and manage lab equipment and personnel
7. Next gen sequencing, RNA-Seq expertise is not required but preferred.
· Design and conduct experiments in molecular and cellular biology, protein biochemistry, and related areas.
· Work with cell culture systems to study cellular processes and protein function.
· Utilize animal models to investigate biological mechanisms and validate experimental findings.
· Analyze and interpret data, and present findings at lab meetings and conferences.
· Collaborate with other team members to achieve research goals.
· Prepare manuscripts for publication in peer-reviewed journals.
Remarks or Special Instructions
Additional Preferred Expertise and Skills (not required):
Advanced skill in adipose biology.
Advanced intracellular signaling pathways.
Advanced flow cytometry, cell sorting
Experience with adeno-, lenti-, and or AAV viral vector generation.
Experience with coding languages such as R.
Education Requirements
PhD in life sciences or related field preferred
Experience Requirements
Not more than 0-1 years of postdoctoral research experience
Strong experience in molecular and cellular biology techniques.
Proficiency in protein biochemistry, including protein expression, purification, and characterization.
Experience with cell culture and animal models.
Knowledge of metabolism and epithelial cell biology is an advantage.
Excellent problem-solving skills and attention to detail.
Strong written and verbal communication skills.
Ability to work independently and as part of a collaborative team.
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