Principal Scientist, ADC Characterization

1 month ago

Boulder, United States SciPro Full time

SciPro is excited to share an extraordinary opportunity with our key client in Colorado who is seeking a Principal Scientist, ADC/Antibody Characterization to join their innovative team.


This is not just another role—our client is backed by a former C-Suite executive from one of the largest global software companies, and they are at the forefront of developing safer and more effective cancer therapies using antibody-drug conjugates (ADCs). They’re pioneering a novel approach that enables programmable entry into tumor cells, and you could be part of this groundbreaking mission.


Position Overview:

We are seeking a dynamic Principal Scientist, Antibody Characterization to join this forward-thinking team. This position offers a unique opportunity to make an immediate impact within a highly visible role. This role reports directly to the CSO and works closely with the CEO to shape and drive the strategy for the protein team. The role is hands-on (70% benchwork) while also offering managerial responsibilities, as you lead a talented four-member team focused on ADC production and analytics.


Key Responsibilities:

  • Lead the purification and characterization of proteins, particularly antibodies derived from mammalian cells.
  • Develop and implement strategies to enhance the team’s capabilities in ADC research and development.
  • Manage and mentor a group of highly experienced scientists (4), fostering an environment of collaboration and innovation.
  • Collaborate cross-functionally to integrate cutting-edge technologies in drug discovery and development.
  • Drive the execution of projects with a focus on achieving high throughput in antibody design and functional assessments.


Requirements:

  • PhD in a relevant field with a strong background in protein purification and characterization.
  • Strong chemical conjugation, and antibody analytical characterization skills (HPLC HIC and SEC, Maleimide chemistry, NHS ester chemistry).
  • Proven expertise in the development and application of ADCs.
  • Must have held at least 2 to 3 direct report
  • Strong written and verbal communication skills, with the ability to convey complex scientific concepts effectively.

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