Stablix- Senior Scientist, Medicinal Chemistry
Found in: Appcast US C2 - 2 weeks ago
Stablix- Senior Scientist, Medicinal Chemistry
The company
Stablix is a venture-backed preclinical stage drug discovery company, pioneering an entirely new field of targeted deubiquitination therapeutics to bring transformative medicines to patients with high unmet medical need. Our platform generates novel bifunctional molecules that selectively recruit deubiquitinases (DUBs) to target proteins to precisely remove ubiquitin for therapeutic advantage. We are a creative and multidisciplinary team of scientists, innovators and leaders dedicated to changing the drug discovery and development paradigm. Stablix has labs and offices in Boston MA and NYC, NY.
The position
Stablix offers the opportunity to work at a big concept biotechnology company. We are seeking motivated, collaborative, and experienced individuals to join the medicinal chemistry team. Equipped with a broad background in synthetic organic chemistry, the successful candidate will have a strong knowledge of hit-to-lead optimization to clinical candidate, and the ability to be dynamic working across multiple projects. This position will be in person in our Boston office.
Duties/Responsibilities:
Contribute to medicinal chemistry strategy that aligned with project goals
Analyze structure-activity relationships to design compounds for lead optimization of biological activity, molecular properties and pharmacokinetic parameters
Work in close collaboration with internal and external chemistry teams to efficiently progress compound optimization and scale up campaign
Collaborate with colleagues across multiple disciplines to rapidly progress leads towards clinical candidates
Communicate medicinal chemistry strategy, objectives, progress & challenges to key stakeholders
Qualifications / Education / Experience
Advanced degree in synthetic/organic/medicinal chemistry
3 to 5+ years of experience in drug discovery and development in a biotech or pharmaceutical setting
Experience working with heterobifunctional molecules desirable
Highly creative and productive with excellent knowledge of synthetic chemistry methodologies
Strong medicinal chemistry and drug design knowledge with a solid understanding of ADME/PK, biology, and pharmacology principles
Experience working with external CRO chemistry teams
Experience being the chemistry lead on multidisciplinary project teams, driving compound progression through hit optimization to development candidates.
Highly collaborative team player with effective communication skills
Proven record of working efficiently in a fast-paced environment with a strong sense of urgency
-
Scientist, Medicinal Chemistry
2 days ago
Boston, United States Jnana Therapeutics Full timeAbout Us Jnana Therapeutics is a clinical-stage biotechnology company leveraging its next-generation RAPID chemoproteomics platform to discover medicines for highly validated, challenging-to-drug targets to treat diseases with high unmet needs. Jnana is focused on developing first- and best-in-class therapies to treat a wide range of diseases, including...
-
Boston, United States Lilly Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
-
Senior Associate Scientist, DMPK
Found in: beBee jobs US - 2 weeks ago
Boston, Massachusetts, United States Cerevel Therapeutics Full timeOur portfolio of pre-commercial neuroscience assets targets a broad range of central nervous system (CNS) disorders, including schizophrenia, epilepsy, Parkinson's disease and substance use disorder.This is an exciting role for a Senior Associate lab scientist to be part of the growing DMPK (Bioanalytical) group here at Cerevel.The ideal candidate will be...
-
Advisor - Chemistry – Genetic Medicines (SMDD)
Found in: beBee jobs US - 2 weeks ago
Boston, Massachusetts, United States Eli Lilly and Company Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
-
Advisor - Chemistry â Genetic Medicines (SMDD)
Found in: beBee S US - 3 weeks ago
Boston, United States Eli Lilly and Company Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
-
Boston, United States BioSpace Full timeJob DetailsAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our...
-
Boston, United States K.A. Recruiting Full timeLooking for a new Med Tech job? My name is Leah and I'm a healthcare recruiter, I'm here to help! I have an awesome Chemistry Med Tech position available near Boston, Massachusetts! Details- Full-time and permanent- Shift: Days- Opportunities for gro Chemistry, Medical Technologist, Chemist, Medical, Scientist, Technologist, Healthcare, Staffing
-
Boston, United States K.A. Recruiting Full timeLooking for a new Med Tech job? My name is Leah and I'm a healthcare recruiter, I'm here to help! I have an awesome Med Tech role available near Boston, Massachusetts! Details- Full-time and permanent- Shift: Days- Opportunities for growth- Full, com Chemistry, Medical Technologist, Chemist, Medical, Scientist, Technologist, Healthcare, Staffing
-
Boston, United States Lilly Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
-
Associate Scientist, Protein Engineering
Found in: beBee jobs US - 2 weeks ago
Boston, Massachusetts, United States Proclinical Staffing Full timeSenior Associate Scientist, Protein Engineering & Bioconjugation - Permanent - OnsiteProclinical is seeking a Senior Associate Scientist, Protein Engineering & Bioconjugation to join a stealth biotech company.The Senior Associate Scientist will be a motivated and curious researcher, with willingness to learn about numerous areas of bioconjugation, chemistry...
-
Director/Sr. Director, Medicinal Chemistry
Found in: Jooble US O C2 - 3 weeks ago
Boston, MA, United States Jnana Therapeutics, Inc. Full timeAbout Us Jnana Therapeutics is a clinical-stage biotechnology company leveraging its next-generation RAPID chemoproteomics platform to discover medicines for highly validated, challenging-to-drug targets to treat diseases with high unmet needs. Jnana is focused on developing first- and best-in-class therapies to treat a wide range of diseases, including...
-
Boston, United States K.A. Recruiting Full timeLooking for a MT/ MLT job? My name is Leah and I'm a healthcare recruiter, I'm here to help! I have a new Medical Technologist Chemistry position available near Boston, Massachusetts! Details- Full-time and permanent- Shifts: Days- Opportunities for Laboratory, Medical Technologist, Scientist, Medical, Chemistry, Clinical, Healthcare, Staffing
-
Boston, United States Eli Lilly Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
-
Boston, United States BioSpace Full timeJob DetailsAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our...
-
Associate Scientist, Protein Engineering
Found in: beBee S US - 2 weeks ago
Boston, United States Proclinical Staffing Full timeSenior Associate Scientist, Protein Engineering & Bioconjugation - Permanent - OnsiteProclinical is seeking a Senior Associate Scientist, Protein Engineering & Bioconjugation to join a stealth biotech company.The Senior Associate Scientist will be a motivated and curious researcher, with willingness to learn about numerous areas of bioconjugation, chemistry...
-
Boston, United States Eli Lilly Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
-
Director â Analytical Chemistry
Found in: beBee S US - 3 weeks ago
Boston, United States Eli Lilly and Company Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
-
Senior Clinical Scientist
2 days ago
Boston, United States Verve Therapeutics Inc Full timeThe Position Verve is seeking an experienced Senior Clinical Scientist to join our team as we continue to advance gene editing medicines for cardiovascular disease into clinical development. In this position, you will be an integral part of the clinical development team supporting the execution of early phase clinical studies. You will report to the Senior...
-
Director â Chemistry
Found in: beBee S US - 3 weeks ago
Boston, United States Eli Lilly and Company Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
-
Director – Analytical Chemistry
Found in: beBee jobs US - 3 weeks ago
Boston, Massachusetts, United States Eli Lilly and Company Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...