Scientist Protein Biochemist, Crystallography Expert
2 weeks ago
Job Title: Scientist Protein Biochemist-Crystallographer
Company: Pledge Therapeutics
Location: Canton MA
About Pledge Therapeutics:
Pledge Therapeutics is an innovative start-up dedicated to advancing treatments in immunology and virology. We are passionate about developing novel therapies addressing unmet medical needs in immune-oncology and viral infections. Leveraging our state-of-the-art discovery platform, we have developed high-quality medicinal leads for multiple exciting drug targets that can potentially revise existing treatment paradigms. Our breakthrough discoveries are ready to be transitioned from the lab to the clinic.
Job Description:
We seek an enthusiastic scientist capable of solving the challenges associated with leading-edge discoveries. The successful candidate will integrate into an international and multidisciplinary team of scientists, engage in different research areas and work cross-functionally with the IO and Virology team to leverage crystallography to solve key molecular structures, produce high-quality proteins and contribute to the development and advancement of novel therapeutic strategies.
This scientist is the vanguard of our R&D efforts, capable of adapting to any situation and responding swiftly to changing conditions. From urgent research studies to critical experiments, this team member executes efficiently and effectively.
Key Responsibilities:
- Leverage crystallography experience to solve crystal structures of key targets/molecules including protein crystallography, initial screening, crystal quality optimization, data collection, and structure determination
- Work cross-functionally with IO / Virology teams to produce proteins, including designing the methodology and performing the purification of proteins of therapeutic interest to provide high-quality material for the advancement of drug discovery campaigns
- Collaborates with biologists, biophysicists, biochemists, structural biologists, and medicinal chemists to develop comprehensive approaches to ensure target viability and address specific project needs
- Establish protocols to characterize target proteins for small molecule
Education and Experience:
- Master / PhD degree in Structural Biology / Protein Biochemistry
- 3-5 years of work experience as a bench scientist in industry (e.g., biotech, pharma)
- Experience Protein Purification for different expression systems using multiple techniques
- Preference will be given to candidates who have direct experience in enzymology and crystallization techniques (co-crystallization, seeding, cross-seeding, soaking, harvesting, and freezing)
- Familiar with chemistry and protein computational techniques
- Champion a “can do" attitude and flexibility to adjust as R&D priorities shift
Job Type: Full-time, Work Permit, Equal Opportunity Employment
-
Canton, Massachusetts, United States Pledge Therapeutics Full timeJob Title: Scientist Protein Biochemist-CrystallographerCompany: Pledge TherapeuticsLocation: Canton, MAAbout Pledge Therapeutics:We are a pioneering start-up dedicated to advancing treatments in immunology and virology. Our mission is to develop novel therapies addressing unmet medical needs in immune-oncology and viral infections. Leveraging our...
-
Scientist Protein Biochemist, Crystallography Expert
4 months ago
Canton, United States Pledge Therapeutics Full timeJob Title: Scientist Protein Biochemist-Crystallographer Company: Pledge TherapeuticsLocation: Canton MAAbout Pledge Therapeutics:Pledge Therapeutics is an innovative start-up dedicated to advancing treatments in immunology and virology. We are passionate about developing novel therapies addressing unmet medical needs in immune-oncology and viral infections....
-
Canton, Massachusetts, United States Pledge Therapeutics Full timeAbout Pledge TherapeuticsPledge Therapeutics is a pioneering biotech company dedicated to advancing innovative treatments in immunology and virology. Our mission is to develop novel therapies addressing unmet medical needs in immune-oncology and viral infections.Job DescriptionWe are seeking a highly skilled scientist to join our international and...
-
Protein Crystallography Scientist
1 month ago
Canton, Ohio, United States Pledge Therapeutics Full timePosition Title: Scientist Protein Biochemist-CrystallographerCompany: Pledge TherapeuticsLocation: Canton MAAbout Pledge Therapeutics:Pledge Therapeutics is a pioneering start-up focused on enhancing treatments in the fields of immunology and virology. Our mission is to create groundbreaking therapies that address significant medical needs in immune-oncology...
-
Protein Crystallography Scientist
1 month ago
Canton, Ohio, United States Pledge Therapeutics Full timePosition Title: Scientist Protein Biochemist-CrystallographerCompany: Pledge TherapeuticsLocation: Canton MAAbout Pledge Therapeutics:Pledge Therapeutics is a pioneering start-up committed to enhancing therapies in the fields of immunology and virology. Our mission is to create innovative treatments that address significant medical needs in immune-oncology...
-
Protein Crystallography Scientist
1 month ago
Canton, Ohio, United States Pledge Therapeutics Full timePosition Title: Scientist Protein Biochemist-CrystallographerCompany: Pledge TherapeuticsLocation: Canton MAAbout Pledge Therapeutics:Pledge Therapeutics is a pioneering start-up focused on enhancing therapies in the fields of immunology and virology. Our mission is to create innovative treatments that meet significant medical needs in immune-oncology and...
-
Protein Crystallography Scientist
1 month ago
Canton, Ohio, United States Pledge Therapeutics Full timePosition Title: Scientist Protein Biochemist-CrystallographerCompany: Pledge TherapeuticsLocation: Canton MAAbout Pledge Therapeutics:Pledge Therapeutics is a pioneering start-up focused on enhancing therapies in the fields of immunology and virology. Our mission is to create groundbreaking treatments that address significant medical needs in immune-oncology...
-
Protein Crystallography Scientist
1 month ago
Canton, Ohio, United States Pledge Therapeutics Full timePosition Title: Scientist Protein Biochemist-CrystallographerCompany: Pledge TherapeuticsLocation: Canton MAAbout Pledge Therapeutics:Pledge Therapeutics is a pioneering start-up focused on enhancing therapies in the fields of immunology and virology. Our mission is to create innovative treatments that meet significant medical needs in immune-oncology and...
-
Protein Crystallography Scientist
1 month ago
Canton, Ohio, United States Pledge Therapeutics Full timePosition Title: Scientist Protein Biochemist-CrystallographerCompany: Pledge TherapeuticsLocation: Canton MAAbout Pledge Therapeutics:Pledge Therapeutics is a pioneering start-up focused on enhancing treatments in the fields of immunology and virology. Our mission is to create groundbreaking therapies that address significant medical needs in immune-oncology...
-
Senior Scientist X-Ray Crystallography Expert
2 weeks ago
Canton, Massachusetts, United States Pledge Therapeutics Full timeAbout the RoleWe are seeking a highly skilled Senior Scientist to join our team at Pledge Therapeutics. As a key member of our international and multidisciplinary team, you will be responsible for leading-edge discoveries in X-Ray Crystallography.Your primary focus will be on leveraging crystallography expertise to solve crystal structures of key...
-
Senior Research Scientist X-Ray Crystallography
4 weeks ago
Canton, Massachusetts, United States Pledge Therapeutics Full timeAbout the RoleWe are seeking a highly skilled and experienced Senior Scientist to join our team at Pledge Therapeutics. As a Senior Scientist, you will play a key role in advancing our research and development efforts in immunology and virology.Key Responsibilities:Leverage your expertise in crystallography to solve crystal structures of key...
-
Senior Scientist X-Ray Crystallography
4 weeks ago
Canton, United States Pledge Therapeutics Full timeJob Title: Senior Scientist Structural Biologist | X-Ray CrystallographyLocation: Greater BostonAbout the Company: Pledge Therapeutics is an innovative start-up dedicated to advancing treatments in immunology and virology. We are passionate about developing novel therapies addressing unmet medical needs in immune-oncology and viral infections. Leveraging our...
-
Senior Scientist X-Ray Crystallography
2 weeks ago
Canton, United States Pledge Therapeutics Full timeJob Title: Senior Scientist Structural Biologist | X-Ray CrystallographyLocation: Greater BostonAbout the Company: Pledge Therapeutics is an innovative start-up dedicated to advancing treatments in immunology and virology. We are passionate about developing novel therapies addressing unmet medical needs in immune-oncology and viral infections. Leveraging our...
-
Senior Scientist X-Ray Crystallography
4 weeks ago
Canton, United States Pledge Therapeutics Full timeJob Title: Senior Scientist Structural Biologist | X-Ray CrystallographyLocation: Greater BostonAbout the Company: Pledge Therapeutics is an innovative start-up dedicated to advancing treatments in immunology and virology. We are passionate about developing novel therapies addressing unmet medical needs in immune-oncology and viral infections. Leveraging our...
-
Protein Purification Senior Scientist
4 weeks ago
Canton, United States Pledge Therapeutics Full timeJob title: Senior Scientist/Protein PurificationLocation: Canton MAJob Description:We seek an enthusiastic and skilled scientist to lead protein purification, production, and characterization efforts within our Rapid Response Group (RRG), a specialized team in our Discovery Division. The RRG operates with a hands-on, mission-focused approach, parachuting...
-
Protein Purification Senior Scientist
1 month ago
Canton, United States Pledge Therapeutics Full timeJob title: Senior Scientist/Protein PurificationLocation: Canton MAJob Description:We seek an enthusiastic and skilled scientist to lead protein purification, production, and characterization efforts within our Rapid Response Group (RRG), a specialized team in our Discovery Division. The RRG operates with a hands-on, mission-focused approach, parachuting...
-
Principal Scientist, Protein
2 weeks ago
Canton, United States Pledge Therapeutics Full timePrincipal Scientist, Protein & Antibody EngineeringAbout Pledge Therapeutics:Pledge Therapeutics is an innovative start-up dedicated to advancing treatments in immunology, oncology, and virology. We are passionate about developing novel therapies that improve the lives of patients. Leveraging our state-of-the-art discovery platform, we have developed...
-
Principal Scientist, Protein
3 weeks ago
Canton, United States Pledge Therapeutics Full timePrincipal Scientist, Protein & Antibody EngineeringAbout Pledge Therapeutics:Pledge Therapeutics is an innovative start-up dedicated to advancing treatments in immunology, oncology, and virology. We are passionate about developing novel therapies that improve the lives of patients. Leveraging our state-of-the-art discovery platform, we have developed...
-
Food Scientist
2 weeks ago
Canton, United States Reiser Full timeFood Scientist / Meat Technologist EXPERIENCE DEVELOPING MEAT/PROTIEN PRODUCTS REQUIRED About Reiser With more than 60 years of success in the food equipment industry, Reiser is recognized worldwide for its high-quality food processing equipment, innovative engineering, and outstanding service and support. Total commitment to our customers is at the core...
-
Food Scientist
1 month ago
Canton, United States Reiser Full timeFood Scientist / Meat Technologist EXPERIENCE DEVELOPING MEAT/PROTIEN PRODUCTS REQUIRED About Reiser With more than 60 years of success in the food equipment industry, Reiser is recognized worldwide for its high-quality food processing equipment, innovative engineering, and outstanding service and support. Total commitment to our customers is at the core...